Genes News and Research

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Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

Medulloblastomas originate much earlier in pregnancy than previously thought and may be preventable

An aggressive type of pediatric brain tumor, medulloblastoma, exists in a pre-malignant form at birth after initially developing during the first or second trimester of pregnancy, according to a new international study.

21 Sep 2022

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

In a new study, researchers assessed the efficacy of the scFv76 antibody against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung damage.

21 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Researchers evaluated the association between guild-level microbiome signature and the severity and prognosis of SARS-CoV-2 infections by a genome-level metagenomic analysis.

21 Sep 2022

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients.

21 Sep 2022

Evidence A.2 lineage of monkeypox is mutating

In a recent study posted to the bioRxiv* preprint server, a team of researchers from India analyzed the whole genome sequences of the monkeypox virus isolated from monkeypox patients with and without international travel histories to understand the phylogenetic relations and genomic evolution of the virus that could contribute to higher transmission rates.

21 Sep 2022

Study reveals increased immunity evasion by Omicron BA.2.75.2

In a recent study posted to the bioRxiv* preprint server, researchers from ETH Zurich, Imperial College London, and Karolinska Institutet identified increased resistance to antibody-mediated neutralization by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineage BA.2.75.2.

21 Sep 2022

Humanized zebrafish could aid in the search for MS drugs

The zebrafish should be known to many aquarium enthusiasts mainly because of its striking pigmentation. However, the characteristic black-blue stripes, to which the animal owes its name, only form over time.

20 Sep 2022

Epigenetic treatment can promote neuronal regrowth in the spinal cord after injury

Currently, spinal cord injury does not have any effective treatments; physical rehabilitation can help patients regain some mobility, but for severe cases the outcomes are extremely limited by the failure of spinal neurons to regenerate naturally after injury.

20 Sep 2022

Epigenetic gene silencing found to be a predictive factor for aggressive breast and ovarian cancer

In a recent study published in JAMA Oncology, investigators from the University of Bergen, in collaboration with the Women's Health Initiative study in the US, reported epigenetic gene silencing in normal tissue to be a predictive factor for triple-negative breast cancer (TNBC) as well as high-grade serous ovarian cancer (HGSOC).

20 Sep 2022

Study identifies genetic variation linked with posterior urethral valves in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a study published today in eLife suggests.

20 Sep 2022

Overload of stress granules enables the growth of obesity-related pancreatic cancer

Obesity is a known risk factor for at least 13 types of cancer, in part because it creates ever-present inflammatory state. For years, one researcher has wondered if there's more to the story than inflammation.

20 Sep 2022

Study identifies common genetic variants associated with musical beat synchronization

The first large-scale genomic study of musicality - published on the cover of today's Nature Human Behaviour - identified 69 genetic variants associated with beat synchronization, meaning the ability to move in synchrony with the beat of music.

19 Sep 2022

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

The wastewater environmental surveillance conducted in Jerusalem, Israel, has detected an increasing population of poliovirus type 2. Furthermore, these viral isolates are associated with vaccine-derived viral strains.

19 Sep 2022

New insights into how the circadian clock may promote healing after traumatic brain injuries

A type of brain cell that can renew itself is regulated by circadian rhythms, providing significant insights into how the body's internal clock may promote healing after traumatic brain injuries (TBI), according to new research from Children's National Hospital.

19 Sep 2022

Genes News and Research

Virology of the human monkeypox virus

New genetically-targeted MND therapy could be a turning point for patient care

Medulloblastomas originate much earlier in pregnancy than previously thought and may be preventable

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Why fatigue from long COVID goes beyond simply feeling tired

Evidence A.2 lineage of monkeypox is mutating

Study reveals increased immunity evasion by Omicron BA.2.75.2

Humanized zebrafish could aid in the search for MS drugs

Epigenetic treatment can promote neuronal regrowth in the spinal cord after injury

Epigenetic gene silencing found to be a predictive factor for aggressive breast and ovarian cancer

Study identifies genetic variation linked with posterior urethral valves in males

Overload of stress granules enables the growth of obesity-related pancreatic cancer

Study identifies common genetic variants associated with musical beat synchronization

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

New insights into how the circadian clock may promote healing after traumatic brain injuries

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

Duke University Hospital selected as Center of Excellence for treating cerebral cavernous malformations

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

eBook: Using iPSCs models for human disease research and drug discovery eBook

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