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New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus

A disorder known as Barrett's esophagus (BE) affects some 200,000 Americans each year. The condition, which is caused by stomach acid damaging the lining of the esophagus, can lead to the development of a serious, potentially fatal cancer of epithelial tissue, known as esophageal adenocarcinoma.

25 Aug 2016

Protein complex could play key role in natural development of stem cells into healthy blood cells

A group of proteins best known for helping to activate all mammalian genes has been found to play a particularly commanding role in the natural development of specialized stem cells into healthy blood cells, a process known as hematopoiesis.

25 Aug 2016

Stem cells contribute to origin of cancer in different organs of mice

The idea that stem cells - special cells that divide to repair and generate tissues - might be the major determinant of cancer risk has provoked great debate in the scientific community.

25 Aug 2016

Salk researchers develop new method to create unlimited numbers of precursor kidney cells

Salk Institute scientists have discovered the holy grail of endless youthfulness--at least when it comes to one type of human kidney precursor cell.

25 Aug 2016

HMS study reveals key instigator of nerve cell damage in ALS patients

Scientists from Harvard Medical School have identified a key instigator of nerve cell damage in people with amyotrophic lateral sclerosis, or ALS, a progressive and incurable neurodegenerative disorder.

25 Aug 2016

New imaging technique may help detect amyloid-related heart failure

A type of heart failure caused by a build-up of amyloid can be accurately diagnosed and prognosticated with an imaging technique, eliminating the need for a biopsy, according to a multicenter study led by researchers at Columbia University Medical Center.

24 Aug 2016

Preimplantation genetic screening using next generation sequencing: an interview with Dr Luis Alcaraz

PGS, Preimplantation Genetic Screening, is a genetic test that analyses biopsied cells from embryos produced by in vitro fertilization (IVF) techniques. PGS determines whether the embryos are chromosomally normal (euploid) or not (aneuploid), thus giving the chance to transfer chromosomally normal embryos that are more apt to successfully implant and develop into a pregnancy.

24 Aug 2016

New study may offer vital clues to understanding how Zika virus affects the developing brain

In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.

24 Aug 2016

Scientists move a step closer to translating BubR1 protein's function into potential cancer therapy

In a paper published recently in the journal eLife, Mayo Clinic scientists take a step toward translating the protein BubR1's function into a potential therapy for cancer.

24 Aug 2016

VUMC receives $11 million renewal grant to advance pulmonary fibrosis research

Vanderbilt University Medical Center has received an $11 million program project renewal grant from the National Heart, Lung and Blood Institute to study the genetics and underlying biological mechanisms that lead to idiopathic pulmonary fibrosis (IPF).

23 Aug 2016

NIH researchers discover rare, lethal inflammatory disease that affects young children

National Institutes of Health researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children. They have also identified anti-inflammatory treatments that ease some of the patients' symptoms: fever, skin rashes, diarrhea, joint pain and overall failure to grow or thrive.

23 Aug 2016

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals).

22 Aug 2016

Neuroscientists demonstrate revolutionary new way of mapping the brain at single-neuron resolution

Neuroscientists today publish in Neuron details of a revolutionary new way of mapping the brain at the resolution of individual neurons, which they have successfully demonstrated in the mouse brain.

19 Aug 2016

Researchers reveal first three-dimensional molecular map of protein linked to many cancers

Walter and Eliza Hall Institute researchers have revealed for the first time the three-dimensional molecular 'map' of a protein that has been pinpointed as a driver of many types of cancers.

19 Aug 2016

Study examines psychological impact of tumor gene testing in subset of NCI-MATCH patients

The ECOG-ACRIN Cancer Research Group has received federal approval to add a quality-of-life research study, COMmunication and Education in Tumor Profiling (EAQ152) or 'COMET' to the NCI-MATCH (EAY131) trial, already underway.

19 Aug 2016

Researchers identify tantalizing target in fight against aggressive form of lung cancer

Researchers at the University of Virginia School of Medicine have discovered a flaw in the armor of the most aggressive form of lung cancer, a weakness that doctors may be able to exploit to slow or even stop the disease.

19 Aug 2016

Checkpoint inhibitor for treatment of NSCLC patients shows indication of added benefit

Nivolumab has been approved since April 2016 as a checkpoint inhibitor for the treatment of adults with locally advanced or metastatic nonsquamous non-small-cell lung cancer (NSCLC) who have already undergone chemotherapy.

19 Aug 2016

Testing lesions in food pipe could provide early and accurate diagnosis of oesophageal cancer

Genetically analysing lesions in the food pipe could provide an early and accurate test for oesophageal cancer, according to research led by Queen Mary University of London, Academic Medical Center in Amsterdam and Arizona State University.

19 Aug 2016

Study highlights racial/ethnic disparities in genomic sequencing

As scientists learn more about which genetic mutations are driving different types of cancer, they're targeting treatments to small numbers of patients with the potential for big payoffs in improved outcomes.

19 Aug 2016

Fruit fly models may help scientists understand underlying mechanism of HPV-induced cancer

Human papillomavirus (HPV) is one of the most common sexually transmitted infections in the United States and has been identified as a primary cause of cervical cancer in women.

19 Aug 2016

Mutation News and Research

New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus

Protein complex could play key role in natural development of stem cells into healthy blood cells

Stem cells contribute to origin of cancer in different organs of mice

Salk researchers develop new method to create unlimited numbers of precursor kidney cells

HMS study reveals key instigator of nerve cell damage in ALS patients

New imaging technique may help detect amyloid-related heart failure

Preimplantation genetic screening using next generation sequencing: an interview with Dr Luis Alcaraz

New study may offer vital clues to understanding how Zika virus affects the developing brain

Scientists move a step closer to translating BubR1 protein's function into potential cancer therapy

VUMC receives $11 million renewal grant to advance pulmonary fibrosis research

NIH researchers discover rare, lethal inflammatory disease that affects young children

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Neuroscientists demonstrate revolutionary new way of mapping the brain at single-neuron resolution

Researchers reveal first three-dimensional molecular map of protein linked to many cancers

Study examines psychological impact of tumor gene testing in subset of NCI-MATCH patients

Researchers identify tantalizing target in fight against aggressive form of lung cancer

Checkpoint inhibitor for treatment of NSCLC patients shows indication of added benefit

Testing lesions in food pipe could provide early and accurate diagnosis of oesophageal cancer

Study highlights racial/ethnic disparities in genomic sequencing

Fruit fly models may help scientists understand underlying mechanism of HPV-induced cancer

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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