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LAG-3 protein structure may be the key to unlocking new cancer treatments

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.

11 Mar 2024

AI method can predict brain metastasis in lung cancer patients

Physicians treating patients with early-stage lung cancer face a conundrum: choosing potentially helpful yet toxic therapies such as chemotherapy, radiation or immunotherapy to knock out the cancer and lessen the risk of it spreading to the brain, or waiting to see if lung surgery alone proves sufficient.

11 Mar 2024

Childhood cancer survivors rarely up to date for recommended surveillance tests

Surviving childhood cancer does not always mean a clean bill of health, as the treatments that eradicate those cancers can put adult survivors at risk of new cancers and other serious health problems.

11 Mar 2024

Social workers bridge the gap in HIV care for hospitalized patients in Tanzania

Researchers at Weill Cornell Medicine have shown that three months of social worker follow-up support to people hospitalized with HIV in Tanzania had health benefits at low cost.

11 Mar 2024

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

A team of investigators from the UCLA Health Jonsson Comprehensive Cancer and the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute was awarded a $3.2 million grant from the National Institutes of Health to identify new ways to prevent and overcome treatment resistance to targeted therapy in patients with all sub-types of cutaneous melanoma, an aggressive form of skin cancer.

11 Mar 2024

Novel genetic link uncovered in generalized pustular psoriasis

A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team's findings, published in the Journal of the American Academy of Dermatology, offer hope for improving diagnosis and therapy.

9 Mar 2024

Scientists transform skin cells into functional eggs in mice

New research from Oregon Health & Science University describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos.

9 Mar 2024

Zika virus live-attenuated vaccine strains show promise in brain cancer treatment

Scientists from Duke-NUS Medical School (Duke-NUS) have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumor growth, while sparing healthy cells.

8 Mar 2024

INTEGRA supports the next generation of synthetic biologists

INTEGRA Biosciences awarded 3 PIPETBOY acu 2 serological pipette controllers to the 2023 iGEM Competition team at Technische Universität Braunschweig (TU_BS) to aid their pioneering research into lithium therapy toxicity testing.

From INTEGRA Biosciences 8 Mar 2024

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Researchers analyzed systematic reviews conducted on the association between autoimmune diseases and pregnancy outcomes.

8 Mar 2024

Diabetes drug dulaglutide may reduce symptoms of depression

The current study highlighted the antidepressant effects of dulaglutide using the CMS depression model. Notably, the potential metabolisms that underlie the antidepressant effect of dulaglutide have been elucidated in this study.

8 Mar 2024

New psychological treatment for epileptic children lowers mental health problems

A new psychological treatment for children with epilepsy, developed by a UCL-led team of scientists, has been shown to reduce mental health difficulties compared to standard care, a new study finds.

7 Mar 2024

Understanding long COVID: A call for better diagnosis and treatment

A recent review in Nature Reviews Microbiology summarizes the complex mechanisms, significant impacts, and the urgent need for enhanced diagnostics and treatments for long COVID, affecting over 65 million people globally with diverse, debilitating symptoms and systemic health issues.

7 Mar 2024

Breakthrough in CRISPR delivery promises safer gene editing

Recent research in PNAS highlights advancements in non-viral, cell-specific delivery methods for CRISPR-Cas systems, emphasizing their potential to enhance research and gene therapy applications by minimizing risks associated with off-target effects and improving targeted delivery.

7 Mar 2024

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

7 Mar 2024