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Simple dietary supplement may provide new approach to boost CAR T cell cancer-fighting power

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

9 Dec 2024

Hospital-acquired pressure ulcers may hinder neurological recovery in spinal cord injury patients

Research led by The Ohio State University Wexner Medical Center and College of Medicine along with scientists at the Charité – Universitätsmedizin Berlin in Berlin, Germany, provides first evidence that hospital-acquired pressure ulcers are a potent risk factor for poor neurological recovery among patients with acute spinal cord injury (SCI).

9 Dec 2024

Pioneering study discovers new genetic links to pancreatic cancer in Brazil

Pancreatic cancer has recently been included in the list of diseases about which Brazil's National Cancer Institute (INCA) periodically publishes statistics.

9 Dec 2024

Can HIIT's metabolic benefits last? New study explores post-exercise sustainability in diabetes

Researchers investigate whether high-intensity interval training-induced metabolic benefits sustain or differ after prolonged training cessation.

9 Dec 2024

Depression genes amplify women's heart disease risk

Study reveals a sex-specific link between genetic risks for psychiatric disorders and cardiovascular diseases (CVDs), with women showing a higher risk of atrial fibrillation, coronary artery disease, and heart failure linked to genetic predisposition to major depression. Menopause and modifiable factors like BMI and smoking amplify these risks.

8 Dec 2024

Genetic factors increase prostate cancer risk for African men

Early testing is key to addressing the rise in cases of prostate cancer in Africa - and it doesn't have to be an invasive procedure.

6 Dec 2024

MRI study offers new insights into celiac disease treatment

Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with coeliac disease, which could be the first step towards finding new ways of treating the condition.

6 Dec 2024

New insights into the mechanisms of "Niemann-Pick type C" in children

In the journal "Science Translational Medicine", scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.

6 Dec 2024

Neighborhood disadvantage found to affect blood pressure and cognition

New research from Wake Forest University School of Medicine suggests that living in a disadvantaged neighborhood is associated with higher blood pressure and lower cognitive scores, even among people who do not have an existing diagnosis of mild cognitive impairment.

6 Dec 2024

New compound HPH-15 offers promising alternative to diabetes medications

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.

6 Dec 2024

Mapping blood system changes offers new hope for leukemia treatments

Researchers at University of California San Diego School of Medicine and their colleagues have developed the first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime.

6 Dec 2024

Study uncovers mechanism behind nutrient scavenging in pancreatic cancer

Cancer cells are like booming cities without urban planners. They expand quickly, and in doing so, the resulting tumors consume more energy and other resources than they can acquire from nearby blood vessels.

6 Dec 2024

Study identifies potential epigenetic biomarker for preeclampsia

Analysis of cheek swabs taken from pregnant women revealed a potential epigenetic biomarker for preeclampsia, a potentially life-threatening condition that often leads to preterm births.

6 Dec 2024

New computational pipeline identifies key biomarkers for Alzheimer's disease

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD).

6 Dec 2024

EZH2 inhibitors enhance effectiveness of cancer immunotherapies

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.

5 Dec 2024

Bioengineers develop implantable sensors to monitor inflammation in real time

Proteins are the building blocks of life, and changes in protein levels can indicate improving health or impending illness, including signs of inflammation.

5 Dec 2024

Frontotemporal dementia disrupts empathy for pain, study reveals

Study reveals diminished brain activity related to empathy for pain in individuals with behavioral variant frontotemporal dementia (bvFTD), using task-based fMRI. Findings show a stark reduction in neural responses tied to affective empathy, highlighting early bvFTD impacts on social cognition.

5 Dec 2024

New framework enhances genetic prediction of drug response and side effects

A UCLA study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as the severity of any side effects.

5 Dec 2024

Researchers develop diabetes prediction system using clinical and genetic data

A research team led by professor Nan-Hee Kim from Korea University's College of Medicine (Nan-Hee Kim and So-Young Park of Department of Endocrinology and Metabolism; Min-Hee Kim and Jae-Young Kim of Health Science Research Center) recently developed a diabetes prediction system using clinical and genetic data. The system was registered for the domestic patent.

5 Dec 2024

Study identifies key immune cells that could protect the brain after cardiac arrest

Despite improvements in CPR and rates of getting patients to the hospital, only about 10 percent of people ultimately survive after out-of-hospital cardiac arrest (OHCA), translating to about 300,000 deaths per year in the United States.

5 Dec 2024