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Breakthrough discovery could lead to new treatments for a variety of CNS disorders

A breakthrough discovery by scientists at the University of Kentucky could someday lead to new treatments for a variety of diseases of the brain, spinal cord and the eye.

18 Jan 2010

Link between dystrophin gene and age of cardiac disease onset in BMD patients identified

Investigators in The Research Institute at Nationwide Children's Hospital have identified a link between specific modifications of the dystrophin gene and the age of cardiac disease onset in patients with Becker muscular dystrophy (BMD). This information could help clinicians provide early cardiac intervention for BMD patients based on genetic testing results performed on a blood sample. These findings are a result of analysis of the largest number of BMD patients to date and are published in the December issue of the journal Circulation: Cardiovascular Genetics.

18 Jan 2010

Researchers discover how cells flatten out as they adhere to internal bodily surfaces

Researchers at the University of Illinois at Chicago College of Medicine have discovered how cells in the body flatten out as they adhere to internal bodily surfaces, the first step in a wide range of important processes including clot formation, immune defense, wound healing, and the spread of cancer cells.

18 Jan 2010

Researchers identify new gene variants associated With glucose, insulin levels

A major international study with leadership from Massachusetts General Hospital (MGH) researchers has identified 10 new gene variants associated with blood sugar or insulin levels. Two of these novel variants and three that earlier studies associated with glucose levels were also found to increase the risk of type 2 diabetes. Along with a related study from members of the same research consortium, associating additional genetic variants with the metabolic response to a sugary meal, the report will appear in Nature Genetics and has been released online.

18 Jan 2010

New study reveals parenthood is associated with lower blood pressure

A new Brigham Young University study found that parenthood is associated with lower blood pressure, particularly so among women.

18 Jan 2010

Research suggests mail-order pharmacies are associated with better medication adherence

Buying medicine by mail may encourage patients to stick to their doctor-prescribed medication regimen, new research suggests.

18 Jan 2010

Scientists manipulate and expand the number of stem/progenitor cells

Scientists at Fred Hutchinson Cancer Research Center have cleared a major technical hurdle to making umbilical-cord-blood transplants a more widely-used method for treating leukemia and other blood cancers.

18 Jan 2010

Evidence suggests insulin pumps may help in maintaining blood glucose levels in type 1 diabetic patients

A new evidence review suggests that using a pump to deliver insulin continuously — instead of taking three or more daily injections — might result in better control of blood sugar for people with type 1 diabetes.

18 Jan 2010

EMA PDCO grants specific waivers for Gamida Cell-Teva JV's StemEx study in paediatric patients

The Gamida Cell-Teva Joint Venture (JV) announced today that the Paediatric Committee (PDCO) of the EMA has granted product specific waivers for StemEx for all subsets of the paediatric population (birth to 17 years of age) in all conditions. The PDCO emphasized that the granting of the waivers should not prevent the JV from considering developing StemEx for children with conditions where there is a need. StemEx is being developed by a joint venture equally owned and operated by Gamida Cell and Teva Pharmaceuticals ( TEVA).

18 Jan 2010

Researchers uncover novel genetic markers for diabetes-related traits

In two major studies published in Nature Genetics today, researchers use biological understanding to dissect the genetics of diabetes. An international team comprising researchers from more than 100 institutions analysed vast suites of genetic data from more than 100,000 people of European descent to uncover the associations.

18 Jan 2010

Early diagnosis can cure endometrial cancer

Postmenopausal women who experience vaginal bleeding should see a doctor promptly. According to the January issue of Mayo Clinic Health Letter, vaginal bleeding is a symptom that occurs early in the course of endometrial cancer, when the chance of a complete cure is the greatest. Even one drop of blood is abnormal in postmenopausal women.

18 Jan 2010

OSA adversely affects glucose control in patients with type 2 diabetes

Obstructive Sleep Apnea (OSA) adversely affects glucose control in patients with type 2 diabetes, according to a study conducted by researchers at the University of Chicago.

18 Jan 2010

Findings could pave way for new therapeutic approaches for Friedreich's ataxia

Elevated levels of DNA damage have for the first time been found in the cellular mitochondria and nuclei of patients with the inherited, progressive nervous system disease called Friedreich's ataxia (FRDA), says a multicenter research team led by an expert from the University of Pittsburgh Cancer Institute (UPCI).

18 Jan 2010

Researchers discover potential treatment for blinding disease

The discovery of an inflammatory mediator key to the blinding effects of diabetic retinopathy is pointing toward a potential new treatment, Medical College of Georgia researchers said.

18 Jan 2010

Bariatric surgery offers a new hope for obese patients

Obesity is a condition that often follows family lines, but bariatric surgery offers hope for breaking this generational pattern.

18 Jan 2010

JDRF and Animas partner to develop an automated system for better control of type 1 diabetes

The Juvenile Diabetes Research Foundation today announced an innovative partnership with Animas Corporation to develop an automated system to help people with type 1 diabetes better control their disease -- the first step on the path to what would be among the most revolutionary advancements in treating type 1 diabetes: the development of an artificial pancreas, a fully automated system to dispense insulin to patients based on real-time changes in blood sugar levels.

18 Jan 2010

Inadequate saliva and fluoride can contribute to tooth decay

Tooth enamel is tough, harder even than skeletal bone. But even with good dental hygiene, the enamel protecting teeth may show signs of decay in older adults. The January issue of Mayo Clinic Health Letter covers what to look out for and what to do to promote an enamel-friendly setting in the mouth. According to the newsletter, two significant contributors to tooth decay are too little saliva and inadequate fluoride.

18 Jan 2010

Dartmouth researchers to develop and market a drug throughout Asia for treatment of CKD

Thanks in part to more than a decade of preclinical work by Dartmouth researchers, a Japanese biopharmaceutical firm is preparing to develop and market throughout Asia a drug for the treatment of chronic kidney disease (CKD).

18 Jan 2010

Scientists discover potential biomarkers to predict the spread of colon cancer

Scientists in China are reporting discovery of two proteins present in the blood, of people with colon cancer that may serve as the potential biomarkers for accurately predicting whether the disease will spread.

18 Jan 2010

Cerus' INTERCEPT platelets therapeutically effective even after seven days of storage

Cerus Corporation announced today that INTERCEPT-treated platelet components were found to be effective for patient support following extended six and seven day storage in a clinical study conducted at four sites in Europe. These data further confirm the safety and therapeutic efficacy of platelets treated with the INTERCEPT Blood System, a pathogen inactivation treatment designed to protect against transfusion-transmitted diseases.

18 Jan 2010

Blood News and Research

Breakthrough discovery could lead to new treatments for a variety of CNS disorders

Link between dystrophin gene and age of cardiac disease onset in BMD patients identified

Researchers discover how cells flatten out as they adhere to internal bodily surfaces

Researchers identify new gene variants associated With glucose, insulin levels

New study reveals parenthood is associated with lower blood pressure

Research suggests mail-order pharmacies are associated with better medication adherence

Scientists manipulate and expand the number of stem/progenitor cells

Evidence suggests insulin pumps may help in maintaining blood glucose levels in type 1 diabetic patients

EMA PDCO grants specific waivers for Gamida Cell-Teva JV's StemEx study in paediatric patients

Researchers uncover novel genetic markers for diabetes-related traits

Early diagnosis can cure endometrial cancer

OSA adversely affects glucose control in patients with type 2 diabetes

Findings could pave way for new therapeutic approaches for Friedreich's ataxia

Researchers discover potential treatment for blinding disease

Bariatric surgery offers a new hope for obese patients

JDRF and Animas partner to develop an automated system for better control of type 1 diabetes

Inadequate saliva and fluoride can contribute to tooth decay

Dartmouth researchers to develop and market a drug throughout Asia for treatment of CKD

Scientists discover potential biomarkers to predict the spread of colon cancer

Cerus' INTERCEPT platelets therapeutically effective even after seven days of storage

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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