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Taiho announces submission of TAS-102 MAA to EMA for treatment of mCRC

Taiho Pharma Europe Ltd., a subsidiary of Japan based Taiho Pharmaceutical Co., Ltd., announced that it has submitted a Marketing Authorisation Application to the European Medicines Agency for TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), an oral combination anticancer drug intended for use in the treatment of refractory metastatic colorectal cancer (mCRC).

2 Mar 2015

Study debunks false reports surrounding risk of hormone therapy

For over a decade, hormone therapy (HT) has been a hot topic in medicine. Unfortunately, women are still confused and concerned about using HT after two federally-funded studies linked HT to potentially serious health risks.

2 Mar 2015

Revolutionary Oral-B Bluetooth-enabled toothbrush, App launched at Mobile World Congress 2015

Oral-B, the worldwide leader in oral care, unveils improvements to its App that connects to its highest performing toothbrushes, by creating seamless brushing routines and allowing for expanded professional guidance, at the 2015 annual GSMA Mobile World Congress meeting in Barcelona, Spain.

2 Mar 2015

Mundipharma launches Remsima® (infliximab), a new-generation value-based monoclonal antibody, in six European markets

Mundipharma International Limited’s network of independent associated companies are launching Remsima® (infliximab) this month in Germany, Italy, UK, Netherlands, Belgium and Luxembourg following expiry of the relevant patents and Supplementary Protection Certificates, having secured distribution rights from Celltrion Healthcare Hungary Kft for Remsima in these markets.

1 Mar 2015

New pharmacological compounds block nerve cell damage in mouse models of MS

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

28 Feb 2015

Chiasma closes $70 million Series E financing round

Chiasma, Inc., a U.S. privately-held biopharma company developing octreotide capsules, its lead product for the orphan condition acromegaly, today announced the closing of a $70 million Series E financing round.

27 Feb 2015

Study: Levodopa-carbidopa intestinal gel improves quality of life in advanced PD patients

Although levodopa remains the "gold standard" to effectively control motor deficits in the treatment of early stage Parkinson's disease (PD), it loses effectiveness as the disease progresses. After four to six years of treatment with oral medications for Parkinson's disease, about 40% of patients experience lack of muscle control (dyskinesias), end-of-dose wearing off, and fluctuations in "On/Off" states.

27 Feb 2015

Study finds correlation between tests for hemoglobin A1c using finger stick and oral blood

It is estimated that 8.1 million of the 29.1 million Americans living with diabetes are undiagnosed and many who have diabetes have poor glycemic control. Given that each year many Americans visit a dental provider but not a primary care provider, dental visits may be an opportune site for diabetes screening and monitoring glucose control for many at-risk patients.

27 Feb 2015

MIT researchers devise new way to make complex emulsions

MIT researchers have devised a new way to make complex liquid mixtures, known as emulsions, that could have many applications in drug delivery, sensing, cleaning up pollutants, and performing chemical reactions.

27 Feb 2015

Bruker-sponsored sixth AFM Biomed conference highlights increasing impact of AFM in biological applications

Bruker recently sponsored the sixth AFM BioMed International Meeting on AFM in Life Sciences and NanoMedicine. Held last month at the Sanford Consortium for Regenerative Medicine in La Jolla, CA, the conference brought together more than 125 scientists from around the world.

From Bruker Nano Surfaces and Metrology 26 Feb 2015

Gates Foundation awards $2.5 million to support development of vaccine-filled microneedles

The Georgia Institute of Technology and Micron Biomedical have been awarded $2.5 million in grants from the Bill & Melinda Gates Foundation to advance the development of dissolvable microneedle patches for polio immunization. The patches will be studied to evaluate their potential role as part of the worldwide efforts to eradicate polio.

25 Feb 2015

Researchers develop revolutionary approach to treat drug-resistant tumors

In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is resistant to the drugs being used. To treat drug-resistant tumors, doctors typically use multiple drugs simultaneously, a practice called combination therapy.

25 Feb 2015

Study finds new approaches to manage anticoagulant-associated intracerebral hemorrhage

Among patients with oral anticoagulation-associated intracerebral hemorrhage (bleeding within the brain), reversal of international normalized ratio (INR; a measure used to determine the clotting tendency of blood while on medication) below a certain level within 4 hours and systolic blood pressure less than 160 mm Hg at 4 hours were associated with lower rates of hematoma (a localized swelling filled with blood) enlargement, and resumption of anticoagulant therapy was associated with a lower risk of ischemic events without increased bleeding complications, according to a study in the February 24 issue of JAMA.

25 Feb 2015

Reslizumab drug appears to reduce risk of severe asthma attacks

An investigational drug appears to cut the risk of severe asthma attacks in half for patients who have difficulty controlling the disorder with standard medications, according to results from two multicenter clinical trials.

25 Feb 2015

PCDS AC system optimizes delivery of anticoagulation drugs, reduces adverse events

Point of Care Anticoagulation software (PCDS AC) optimizes delivery of anticoagulation drugs and reduces adverse events associated with anticoagulation therapy. The software was designed and developed in collaboration with leading clinical thrombosis experts, and is a decision support tool that takes the complexity out of AC management by providing a real-time AC dashboard. With intuitive, predictive clinical decision support, PCDS AC transforms evidence-based guidelines into intelligent tools that measure and improve AC therapy outcomes.

25 Feb 2015

Patients battling sleep apnea find relief from Zzoma device

Thousands of patients in the U.S. and Europe battling positional obstructive sleep apnea (OSA) are finding relief from Zzoma, an FDA-cleared medical device designed by physicians at Sleep Specialists, LLC.

25 Feb 2015

Two Glenmark manufacturing facilities in India win Greentech Environment Gold Award - 2015

Two manufacturing facilities of Glenmark located in Goa and Nashik bagged the prestigious 'Greentech Environment Gold Award - 2015' for Excellence in Environment Management at a ceremony in Kolkata recently. Greentech Environment Awards are presented ever year to companies/units in India demonstrating the highest level of commitment to Environmental Management across different sectors.

25 Feb 2015

MPP, MSD sign licensing agreement for paediatric formulations of raltegravir

The Medicines Patent Pool announced a licence today with MSD, known as Merck in the United States and Canada, for paediatric formulations of raltegravir, a key medicine approved for children living with HIV four weeks of age and older.

24 Feb 2015

Shire announces acquisition of Meritage Pharma

Shire plc and Meritage Pharma, Inc. announced today that Shire has acquired Meritage, a privately-held company, for an upfront fee of $70 million and additional contingent payments based on the achievement of development and regulatory milestones.

24 Feb 2015

Study reveals how household net worth affects breast cancer care

Household net worth is a major and overlooked factor in adherence to hormonal therapy among breast cancer patients and partially explains racial disparities in quality of care. The findings suggest that physicians, health insurers, and policy makers need to pay more attention to this economic variable to ensure that breast cancer patients receive this potentially life-saving treatment.

24 Feb 2015

Oral News and Research

Taiho announces submission of TAS-102 MAA to EMA for treatment of mCRC

Study debunks false reports surrounding risk of hormone therapy

Revolutionary Oral-B Bluetooth-enabled toothbrush, App launched at Mobile World Congress 2015

Mundipharma launches Remsima® (infliximab), a new-generation value-based monoclonal antibody, in six European markets

New pharmacological compounds block nerve cell damage in mouse models of MS

Chiasma closes $70 million Series E financing round

Study: Levodopa-carbidopa intestinal gel improves quality of life in advanced PD patients

Study finds correlation between tests for hemoglobin A1c using finger stick and oral blood

MIT researchers devise new way to make complex emulsions

Bruker-sponsored sixth AFM Biomed conference highlights increasing impact of AFM in biological applications

Gates Foundation awards $2.5 million to support development of vaccine-filled microneedles

Researchers develop revolutionary approach to treat drug-resistant tumors

Study finds new approaches to manage anticoagulant-associated intracerebral hemorrhage

Reslizumab drug appears to reduce risk of severe asthma attacks

PCDS AC system optimizes delivery of anticoagulation drugs, reduces adverse events

Patients battling sleep apnea find relief from Zzoma device

Two Glenmark manufacturing facilities in India win Greentech Environment Gold Award - 2015

MPP, MSD sign licensing agreement for paediatric formulations of raltegravir

Shire announces acquisition of Meritage Pharma

Study reveals how household net worth affects breast cancer care

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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