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FDA-approved cancer drug blunts SARS-CoV-2 protein's detrimental effects

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2 - the virus that causes COVID-19 – and then used an FDA-approved cancer drug to blunt the viral protein's detrimental effects. In their experiments in fruit flies and human cell lines, the team discovered the cell process that the virus hijacks, illuminating new potential candidate drugs that could be tested for treating severe COVID-19 disease patients.

29 Mar 2021

Varied physical activity can promote well-being and better mental health

The recommendations are clear: physical activity is good for mental health. But it also depends on how varied it is. That's what a new study by researchers at the University of Basel shows, pointing to one of the reasons why well-being suffers during the pandemic.

29 Mar 2021

Researchers propose new standards to measure moisture leaks into bionic devices

Applied physicists at the University of Sydney have proposed new standards to measure moisture leaks into bionic devices such as pacemakers, cochlear hearing implants and retinal replacements.

29 Mar 2021

Low-intensity exercise not enough to counteract effects of long-term weightlessness on the heart

As NASA seeks to build a lunar outpost, visit Mars and commercialize spaceflight, the long-term effects of weightlessness on the human heart are of critical importance, according to researchers.

29 Mar 2021

Low-cost hypertension management intervention can be cost-effectively scaled up in rural South Asia

A low-cost intervention to improve hypertension--or high blood pressure (BP)--prevention and management can be cost-effectively scaled up for rural communities in low- and middle-income countries, according to findings from a multi-country trial published in The Lancet Global Health.

29 Mar 2021

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) -- the virus that causes cold sores, as well as genital herpes -- activate gene expression in neurons.

29 Mar 2021

GlyNAC could improve many age-associated defects in older humans

A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC - a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione - could improve many age-associated defects in older humans to improve muscle strength and cognition, and promote healthy aging.

29 Mar 2021

New model for analyzing the effects of irradiation on skin in laser treatments

Laser treatment is now commonplace across various fields of medicine including dermatology, where it is commonly used to remove scars, wrinkles, and freckles.

29 Mar 2021

Apes mount a much stronger early immune response compared to African and Asian monkeys

A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, highlighting the importance of choosing the right animal model for the right questions.

29 Mar 2021

Study investigates SARS-CoV-2 infection in asymptomatic dental patients

Asymptomatic carriage of SARS-CoV-2 is a potentially significant source of transmission, yet remains relatively poorly understood.

29 Mar 2021

Restricting excessive consumption of added sugars may reduce NAFLD risk in children

A review of more than 20 studies by researchers at Arizona State University and the Translational Genomics Research Institute, an affiliate of City of Hope, suggests that nonalcoholic fatty-liver disease (NAFLD) is a growing dietary problem for children across the globe.

29 Mar 2021

Study shows safety, efficacy of percutaneous thermal ablation for treating metastatic gynecologic cancers

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center found using percutaneous image guided needle based thermal ablation -- the precise application of extreme heat or cold to a tumor using sophisticated ultrasound, CT or MRI in a single outpatient session -- is a safe and effective adjunctive therapy for the local control of metastatic gynecologic cancers throughout lungs, liver, soft tissues in the abdomen and pelvis and bones in patients with advanced localized cancers unresponsive to systemic therapy.

29 Mar 2021

Advanced technology provides a fine-grained picture of lung pathology in COVID-19

A team led by investigators at Weill Cornell Medicine and NewYork-Presbyterian has used advanced technology and analytics to map, at single-cell resolution, the cellular landscape of diseased lung tissue in severe COVID-19 and other infectious lung diseases.

29 Mar 2021

Intelligent near-infrared vein scanner may make blood draws much easier

Researchers from Skoltech have developed an early prototype of a medical imaging system that uses neural networks to analyze near-infrared images of veins and project a venous pattern onto a patient's body - this may make blood draws much easier and less of a nuisance for patients with difficult access to veins.

29 Mar 2021

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability.

29 Mar 2021

Study: Common medications are often derived from animal byproducts

More physicians and pharmacists are advocating for patients to be made aware of animal byproducts contained in common medications, according to new research in the Journal of Osteopathic Medicine.

29 Mar 2021

Long-term, regular use of baby aspirin may reduce risk of colorectal cancer death

Long-term, regular use of baby aspirin - at least 15 times per month - prior to a diagnosis of colorectal cancer (CRC) may reduce the risk of death from the disease by limiting the spread of cancerous tumors pre-diagnosis, according to a study led by Cedars-Sinai Cancer researchers.

29 Mar 2021

Researchers make a breakthrough in the quest for an AMD cure

Age-related macular degeneration (AMD), which leads to a loss of central vision, is the most frequent cause of blindness in adults 50 years of age or older, affecting an estimated 196 million people worldwide. There is no cure, though treatment can slow the onset and preserve some vision.

29 Mar 2021

UVA-led researchers urge rapid action to better prepare for the next pandemic

An international team of researchers led by a University of Virginia School of Medicine professor is warning that scientists must better prepare for the next pandemic - and has developed a plan to do just that.

29 Mar 2021

Study investigates the effects of depression on visual perception

Researchers specialized in psychiatry and psychology at the University of Helsinki investigated the effects of depression on visual perception.

29 Mar 2021

Research News and Research

FDA-approved cancer drug blunts SARS-CoV-2 protein's detrimental effects

Varied physical activity can promote well-being and better mental health

Researchers propose new standards to measure moisture leaks into bionic devices

Low-intensity exercise not enough to counteract effects of long-term weightlessness on the heart

Low-cost hypertension management intervention can be cost-effectively scaled up in rural South Asia

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

GlyNAC could improve many age-associated defects in older humans

New model for analyzing the effects of irradiation on skin in laser treatments

Apes mount a much stronger early immune response compared to African and Asian monkeys

Study investigates SARS-CoV-2 infection in asymptomatic dental patients

Restricting excessive consumption of added sugars may reduce NAFLD risk in children

Study shows safety, efficacy of percutaneous thermal ablation for treating metastatic gynecologic cancers

Advanced technology provides a fine-grained picture of lung pathology in COVID-19

Intelligent near-infrared vein scanner may make blood draws much easier

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

Study: Common medications are often derived from animal byproducts

Long-term, regular use of baby aspirin may reduce risk of colorectal cancer death

Researchers make a breakthrough in the quest for an AMD cure

UVA-led researchers urge rapid action to better prepare for the next pandemic

Study investigates the effects of depression on visual perception

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