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Preclinical data of Geron's telomerase inhibitor drug published

Geron Corporation today announced the publication of preclinical data demonstrating that its telomerase inhibitor drug, imetelstat (GRN163L), inhibited telomerase activity and reduced tumor size in xenograft models of glioblastoma, and inhibited the activity of glioblastoma stem cells in culture.

6 Jan 2010

Cancer Research UK and CRT to undertake phase I clinical trial of DI-B4

CANCER RESEARCH UK and Cancer Research Technology (CRT), the charity's development and commercialisation arm, are to undertake a phase I clinical trial of an investigational monoclonal antibody1 drug from Merck KGaA, Darmstadt, Germany, called DI-B4 - it is announced today (Monday).

6 Jan 2010

Vitamin D deficiency may contribute to higher risk of death among African-Americans compared to whites

Vitamin D deficiency may contribute to a higher number of heart and stroke-related deaths among black Americans compared to whites, according to a University of Rochester Medical Center study.

6 Jan 2010

Insulet and Ypsomed AG sign distribution agreement

Insulet Corporation, the leader in tubing-free insulin pump technology with its OmniPod® Insulin Management System, and Ypsomed AG (SIX Swiss Exchange: YPSN), a leading independent diabetes specialist and technology provider of innovative injection systems for self-medication in Europe, today announced an exclusive agreement for the distribution of the OmniPod Insulin Management System in nine countries across Europe, as well as China and Australia.

5 Jan 2010

Swedish study opens new potential for combating resistant bacteria

Neisseria meningitidis, the meningococcus, is a bacterium that can cause diseases with high fatality rates, and there has therefore been considerable concern that, like other bacteria, it might become resistant to antibiotics. But now a study from örebro University and örebro University Hospital in Sweden shows that there has not been any increase in resistant meningococci in Sweden over the last 15 years. According to researcher Sara Thulin Hedberg, the reason for this may be that it is not especially advantageous for bacteria to develop resistance.

5 Jan 2010

Fish oil supplement now available in water-soluble drink

Nordic Naturals, the industry leader in omega-3 fish oil, introduces Omega-3 Effervescent, an innovative way to enjoy fish oil supplementation via a water-soluble drink mix containing EPA and DHA in a delicious orange flavor.

5 Jan 2010

Philips DirectLife, a new interactive fitness program launched

Philips is delivering on their commitment to be the leader in health and well-being with the launch of Philips DirectLife, a new customized, interactive fitness program that offers a fun and simple solution to people eager to adopt a more active lifestyle.

5 Jan 2010

Women's bodies and minds respond differently to sexual arousal

Women's minds and genitals respond differently to sexual arousal, whereas in men, the responses of the body and mind are more in tune with each other, according to Assistant Professor Meredith Chivers, from Queen's University in Kingston, Canada, and her international collaborators, Michael Seto, Martin Lalumi-re, Ellen Laan, and Teresa Grimbos. Their meta-analysis1 of the extent of agreement between subjective ratings and physiological measures of sexual arousal in men and women is published online this week in Springer's journal Archives of Sexual Behavior.

5 Jan 2010

NQF endorses 70 measures to improve gathering of clinical electronic data

As an incremental step toward wider use of electronic data platforms to measure, report, and improve quality, the National Quality Forum (NQF) has endorsed 70 measures that combine data from two or more common electronic sources such as administrative claims, pharmacy and laboratory systems, and registries.

5 Jan 2010

Subjective experience of sexual arousal and corresponding physiological genital response linked to gender

New research led by Queen's University Psychology professor Meredith Chivers finds that men's reports of feeling sexually aroused tend to match their physiological responses, while women's mind and body responses are less aligned.

5 Jan 2010

SSHE starts off "Seattle Sutton's 2010 Slim Down" weight loss contest

Seattle Sutton's Healthy Eating (SSHE), the premier meal replacement company in the country, kicks off today its weight loss contest called Seattle Sutton's 2010 Slim Down.

5 Jan 2010

Androgen receptor plays critical role in wound healing

A molecular receptor pivotal to the action of male hormones such as testosterone also plays a crucial role in the body's ability to heal, report scientists in the December issue of the Journal of Clinical Investigation.

5 Jan 2010

Elevated diabetes risk associated with smoking cessation, but lifestyle changes can help combat risk

Cigarette smoking is a well-known risk factor for type 2 diabetes, but new research from Johns Hopkins suggests that quitting the habit may actually raise diabetes risk in the short term.

5 Jan 2010

Neuronal protein could be a promising anti-cancer target

By lowering the level of a neuronal protein, researchers halted the growth of blood vessels that tumors rely on for survival. The findings are reported online in the Journal of Experimental Medicine (www.jem.org) on Jan. 4.

5 Jan 2010

Highlights of January 2010 'Ophthalmology'

This month's Ophthalmology, the journal of the American Academy of Ophthalmology, includes a research review of the effects of Vitamins C and E and magnesium on diabetic retinopathy and findings from the first large study of vision problems in Hispanic and African-American infants and young children.

5 Jan 2010

"Nanoworms" and doxorubicin loaded hollow nanoparticles to fight cancer

A team of researchers in California and Massachusetts has developed a "cocktail" of different nanometer-sized particles that work in concert within the bloodstream to locate, adhere to and kill cancerous tumors.

5 Jan 2010

Protein interaction linked to AMD

Researchers at University College London say they have gleaned a key insight into the molecular beginnings of age-related macular degeneration, the No. 1 cause of vision loss in the elderly, by determining how two key proteins interact to naturally prevent the onset of the condition.

5 Jan 2010

Anti-aromatase phytochemicals in pomegranates reduce hormone-dependent breast cancer

Eating fruit, such as pomegranates, that contain anti-aromatase phytochemicals reduces the incidence of hormone-dependent breast cancer, according to results of a study published in the January issue of Cancer Prevention Research, a journal of the American Association for Cancer Research.

5 Jan 2010

Study shows increasing number of U.S. adults are taking antidepressants and antipsychotic medications

An increasing number of U.S. adults are being prescribed combinations of antidepressants and antipsychotic medications, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

5 Jan 2010

Anti-inflammatory prescription drug reduces the risk of common skin cancer in humans

A widely-available anti-inflammatory prescription drug can reduce the risk of a common skin cancer in humans, according to a researcher at Stanford's School of Medicine.

5 Jan 2010