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Australian researchers find new drug target for preventing the spread of malaria

Australian researchers have found a new drug target for stopping the spread of malaria, after successfully blocking the world's deadliest malaria parasite - Plasmodium falciparum - from completing the 'transmission stage' of its lifecycle.

17 Dec 2019

Antioxidant in green tea plant could be key to fighting tuberculosis

An antioxidant found in the green tea plant could become key to tackling tuberculosis one day, a team of international scientists led by Nanyang Technological University, Singapore has found.

17 Dec 2019

Researchers block malaria parasite’s ability to spread infection

Researchers have discovered a new way to prevent the deadliest malaria parasite from spreading infection.

17 Dec 2019

Modified stroke drug boosts injury repair in rats with spinal cord damage

Adding a modified stroke drug to stem cells used to treat rats with spinal injury boosted the therapy and motor activity.

17 Dec 2019

Stroke drug improves stem cell therapy in rat spinal cord injury models

Four months after treating them, Yasuhiro Shiga, MD, PhD, checked on his rats. Walking into the lab, he carried minimal expectations.

17 Dec 2019

Simple, new test can detect dangerous levels of fluoride in drinking water

Northwestern University synthetic biologists developed a simple, inexpensive new test that can detect dangerous levels of fluoride in drinking water.

16 Dec 2019

The sympathetic nervous system can modulate action of defense cells in autoimmune disease

The results of a study conducted in Brazil suggest that the sympathetic nervous system - the part of the autonomous nervous system that controls responses to danger or stress - can modulate the action of defense cells in patients with autoimmune diseases.

16 Dec 2019

KAUST researchers develop electronic biosensor powered using glucose in bodily fluids

An electronic biosensor powered using the glucose in bodily fluids has been developed by KAUST researchers. The device pairs an electron-transporting polymer with an enzyme that extracts electrons from its reaction with glucose to drive its circuitry.

16 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Neuroscientists develop new method for uniquely targeted gene therapy

Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body that needs to be treated. The researchers believe that the new technology can be likened to dramatically accelerating evolution from millions of years to weeks.

13 Dec 2019

Research reveals how skeletal muscle communicates with the brain regarding feeding behavior

The brain determines when it is time to feed - but how does it know? Findings from St. Jude Children's Research Hospital provide new understanding of how the brain orchestrates this process.

12 Dec 2019

Research suggests contributory role of 'Asian glow' mutation and alcohol to Alzheimer’s

A new study from Stanford, published on December 12 in the journal Acta Neuropathologica Communications, suggests that an important enzyme that helps break down alcohol in the body is defective in patients with Alzheimer’s disease (AD). Understanding its relationship with alcohol and with genes that predispose to AD could help avert the latter in humans at risk.

12 Dec 2019

Scientists solve 3D structure of vaccinia virus RNA polymerase

For viruses to multiply, they usually need the support of the cells they infect. In many cases, only in their host's nucleus can they find the machines, enzymes and building blocks with which they can multiply their genetic material before infecting other cells.

12 Dec 2019

Harvard scientists demonstrate possible strategy for achieving herpes virus control

The herpes simplex virus, commonly known as the cold sore virus, is a devious microbe.

12 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019