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In vitro skeletal muscle models could lead to personalized medicine for type 2 diabetes

Abnormally high blood sugar (glucose) levels can result in Type 2 diabetes when things go awry with the body's skeletal muscle, which plays a key role in regulating glucose.

13 Sep 2022

Study uncovers how air pollution can trigger lung cancer in individuals with no history of smoking

A new study revealed a link between air pollution and lung cancer in non-smokers.

13 Sep 2022

How effective is vitamin D supplementation in COVID-19?

The current paper addresses the considerable evidence now supporting the efficacy of vitamin D in COVID-19, as well as its safety.

13 Sep 2022

Treg transplantation improves bone remodeling, study says

The building blocks of a structure consist of load-bearing elements that rarely change despite renovations or repairs. They remain intact and consistent over time, but in the human body, our building blocks do just the opposite.

13 Sep 2022

Age-related changes in microbiome composition affects brain macrophages

Scientists review the impact of age-related gut microbiome composition on age-associated diseases caused by dysfunctional macrophages within the brain.

13 Sep 2022

The impact of the infant gut microbiome on vaccine efficacy

A new study reports the effect of the infant gut microbiome on vaccine efficacy.

13 Sep 2022

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

N-dihydrogalactochitosan shows promise as a mucosal vaccine adjuvant against SARS-CoV-2

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated the efficacy of a novel biopolymer, N-dihydrogalactochitosan (GC), as an adjuvant for next-generation mucosal coronavirus disease 2019 (COVID-19) vaccine.

12 Sep 2022

Review: Arthritogenic alphaviruses and host type I IFN responses

Announcing a new article publication for Zoonoses journal. Arthritogenic alphaviruses, such as Ross River virus, chikungunya virus and O'nyong-nyong virus, cause endemic disease globally and are a major public health concern.

12 Sep 2022

Study reveals two distinct types of obesity with physiological and molecular differences

A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication.

12 Sep 2022

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

Certain drugs used to treat COVID-19 patients - including remdesivir, dexamethasone and antibiotics for associated bacterial infections - persist through wastewater treatment and may occur in waterways at levels high enough to negatively affect aquatic organisms, according to a new study led by researchers at Penn State.

12 Sep 2022

The long-term clinical status of pediatric patients after testing positive for COVID-19

A recent study found that the most common long COVID symptoms in the pediatric population showed a higher prevalence among patients in the age range of 6-17 years and were identical to those reported in adults.

12 Sep 2022

Interferon response induced by Omicron BA.1 and BA.5 prevents influenza A infection

In a recent study posted to the bioRxiv* preprint server, researchers in Germany and the United Kingdom investigated the interferon responses induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and SARS-CoV-2 Omicron sub-variants BA.1 and BA.5, and their efficacy in protecting cells from influenza A virus super-infection.

12 Sep 2022

Long COVID linked to persistence of SARS-CoV-2 spike protein in blood

A new study reports SARS-CoV-2 spike antigen and cytokine levels in a sample of infected individuals, of which a subset had long COVID.

11 Sep 2022

ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, which expanded its focus to conduct research into COVID-19, today announced the initiation of STOMP (Study of Tecovirimat for Human Monkeypox Virus), or A5418, a phase 3, randomized, placebo-controlled, double-blind trial evaluating the safety and efficacy of tecovirimat for the treatment of human monkeypox.

9 Sep 2022

Phase 3 clinical trial commences to evaluate antiviral for monkeypox

A Phase 3 clinical trial evaluating the antiviral tecovirimat, also known as TPOXX, is now enrolling adults and children with monkeypox infection in the United States.

9 Sep 2022

Gut microbes can also impact a person's neurological and emotional health, UTSW researcher says

The role of the microbiome in intestinal and systemic health has garnered close attention among researchers for many years.

9 Sep 2022

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

9 Sep 2022

Monkeypox can sometimes lead to encephalitis, confusion or seizures

Monkeypox can sometimes lead to neurological complications such as encephalitis (brain inflammation), confusion or seizures, finds a new review of evidence led by a UCL researcher.

9 Sep 2022

Inflammation News and Research

In vitro skeletal muscle models could lead to personalized medicine for type 2 diabetes

Study uncovers how air pollution can trigger lung cancer in individuals with no history of smoking

How effective is vitamin D supplementation in COVID-19?

Treg transplantation improves bone remodeling, study says

Age-related changes in microbiome composition affects brain macrophages

The impact of the infant gut microbiome on vaccine efficacy

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

Blocking FNDC5 prevents cancer-induced cachexia in mice

N-dihydrogalactochitosan shows promise as a mucosal vaccine adjuvant against SARS-CoV-2

Review: Arthritogenic alphaviruses and host type I IFN responses

Study reveals two distinct types of obesity with physiological and molecular differences

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

The long-term clinical status of pediatric patients after testing positive for COVID-19

Interferon response induced by Omicron BA.1 and BA.5 prevents influenza A infection

Long COVID linked to persistence of SARS-CoV-2 spike protein in blood

ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

Phase 3 clinical trial commences to evaluate antiviral for monkeypox

Gut microbes can also impact a person's neurological and emotional health, UTSW researcher says

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Monkeypox can sometimes lead to encephalitis, confusion or seizures

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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