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Cardiologists receive K23 research grant from NIH

Brian H. Annex, M.D., chief of the Division of Cardiovascular Medicine at the University of Virginia Health System, says he feels like the coach of a championship team. "Going three for three is truly extraordinary," he says with a mixture of pride and awe in his voice.

10 Dec 2009

EC grants orphan drug designation for MP4CO for treating sickle cell disease

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen and other gas delivery, today announced that the European Commission (EC) has granted orphan medicinal product designation for MP4CO for the treatment of sickle cell disease.

10 Dec 2009

Initiation of dose-finding study to evaluate safety and efficacy of MP4OX treatment

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen delivery, today announced the initiation of a dose-finding study designed to evaluate the safety and efficacy of MP4OX treatment plus standard of care in severely injured trauma patients with lactic acidosis due to hemorrhagic shock.

10 Dec 2009

New health study reveals Ontario women less likely to receive cardiac care than men

Gender differences persist in the quality of cardiac care across Ontario, according to a health study by researchers at St. Michael's Hospital and the Institute for Clinical Evaluative Sciences (ICES).

10 Dec 2009

Ovu-Trac kit for successful family planning

A recent British study revealed that over a third of the female test subjects could not recognize their own signs of fertility. Accurately identifying the signs of ovulation and how they relate to a woman's fertile phase is the key to successful family planning. However, just like anything else, it takes time to learn.

10 Dec 2009

USC Fetal Therapy Program achieves improved survival rate in TTTS fetal surgery

A Southern California fetal surgery institute, one of only a handful in the United States, has posted enormously successful rates in treating a dangerous disorder that affects 10 percent of unborn identical twins.

10 Dec 2009

Scientists discover the potential basis for urine test to diagnose CAP

Scientists are reporting a discovery of the potential basis for a urine test to diagnose community-acquired pneumonia (CAP), a difficult-to-diagnose disease that is the sixth leading cause of death in the United States.

10 Dec 2009

Second pivotal Phase 3 trial to evaluate investigational Lp-PLA2 inhibitor darapladib initiated

Attached is a press release issued earlier this morning by GlaxoSmithKline, announcing that GSK has initiated its second pivotal Phase 3 trial to evaluate the efficacy of long-term treatment with the investigational Lp-PLA2 inhibitor darapladib in men and women with acute coronary syndrome (ACS).

10 Dec 2009

National Heart Lung and Blood Institute of NIH awards Grand Opportunities grant to BMC

Boston Medical Center (BMC), today announced that it has been awarded a Grand Opportunities (GO) grant by the National Heart Lung and Blood Institute of the National Institutes of Health (NIH).

9 Dec 2009

New research shows increase risk of cardiovascular disease for people on low-carbohydrate high-fat diets

New scientific research has shown that low-carbohydrate high-fat diets, made popular by the likes of the Atkins diet, do not achieve more weight loss than low-fat high-carbohydrate diets. Worryingly, the research, lead by Dr Steven Hunter from the Royal Victoria Hospital, Belfast, also shows significantly increased risks of cardiovascular disease for people following low-carbohydrate high-fat diets

9 Dec 2009

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that "mini" stem cell transplantation may safely reverse severe sickle cell disease in adults.

9 Dec 2009

Also in global health news: Illegal drug trade in E. Africa; Somalia humanitarian crisis; alcohol, IV drug use in Russia; HIV/AIDS in China; FBOs engage in HIV fight

"[D]ozens of people" from China's Henan province who contracted HIV/AIDS from blood transfusions "demonstrated in front of the country's health ministry in Beijing" to highlight the challenges facing Chinese AIDS patients, the Irish Times reports.

9 Dec 2009

NIH awards Lentigen a SBIR grant for program to generate Hepatitis C Virus-Like Particles

Lentigen Corporation, a biotechnology company specializing in the development and manufacture of lentiviral gene delivery technologies, announced today that it has received a National Institutes of Health (NIH) small business innovation research (SBIR) grant for a program on "A Novel Method of Generating Hepatitis C Virus-Like Particles using Lentivirus". In this program, Lentigen will collaborate with Epixis SA (Paris, France).

9 Dec 2009

MLL team finds 454 Sequencing technology promising for leukemia genetic characterization

This week at the 51st American Society for Hematology Annual Meeting, a team of researchers from the MLL Munich Leukemia Laboratory presented results from a series of groundbreaking studies which explore alternative, high-throughput 454 Sequencing methods for distinguishing and characterizing the many forms of leukemia and myeloproliferative disorders.

9 Dec 2009

Misuse of blood thinners in dialysis patients reported

Reuters/ABC News reports on research published in the Journal of the American Medical Association that examined the misuse of two blood thinners - Lovenox and Integrilin - in "about 20 percent of kidney dialysis patients who undergo a procedure to open a blocked artery [who] are given the wrong blood clot medicine, increasing the chances of significant bleeding, researchers said Tuesday.

9 Dec 2009

NPH acquires an exclusive license from UCLA for a suite of supramolecular nanoparticle technologies

NanoPacific Holdings, Inc. (NPH) announces the acquisition of an exclusive license from University of California at Los Angeles (UCLA) for a suite of supramolecular nanoparticle technologies. Under the terms of the agreement between NPH and UCLA, NPH will have an exclusive worldwide license of a system composed of a ternary mixture of modular components that self-assemble into supramolecular nanoparticles.

9 Dec 2009

Watson Pharmaceuticals' RAPAFLO demonstrates safety and tolerability in BPH treatment

Watson Pharmaceuticals, Inc. today announced that the results of an open-label extension of two Phase 3 studies, published in the December issue of the peer-reviewed journal Urology, demonstrate long-term safety and tolerability of RAPAFLO® (silodosin) for up to 52 weeks of treatment. RAPAFLO® is an effective and uniquely selective alpha blocker for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH), the number one reason patients visit urologists.

9 Dec 2009

CORD:USE Cord Blood Bank awarded contract to supply blood units for the NCBI

CORD:USE Cord Blood Bank is proud to announce that the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services has awarded CORD:USE Cord Blood Bank a three-year, multi-million dollar contract to expand the supply of cord blood units for the National Cord Blood Inventory (NCBI).

9 Dec 2009

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

Sangamo BioSciences, Inc. announced today the presentation of preliminary data from the Phase 2 clinical trial of its ZFP Therapeutic(TM) program to develop SB-509 as a treatment for amyotrophic lateral sclerosis (ALS) at a Work in Progress session at the 20th International Symposium on ALS/MND held in Berlin, Germany.

9 Dec 2009

Clinical trial results demonstrate greater efficacy of nilotinib over imatinib for Ph+ CML

In a large clinical trial, nilotinib demonstrated greater efficacy over the current gold standard treatment, imatinib, in adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukaemia (Ph+ CML) in the chronic phase.

9 Dec 2009

Blood News and Research

Cardiologists receive K23 research grant from NIH

EC grants orphan drug designation for MP4CO for treating sickle cell disease

Initiation of dose-finding study to evaluate safety and efficacy of MP4OX treatment

New health study reveals Ontario women less likely to receive cardiac care than men

Ovu-Trac kit for successful family planning

USC Fetal Therapy Program achieves improved survival rate in TTTS fetal surgery

Scientists discover the potential basis for urine test to diagnose CAP

Second pivotal Phase 3 trial to evaluate investigational Lp-PLA2 inhibitor darapladib initiated

National Heart Lung and Blood Institute of NIH awards Grand Opportunities grant to BMC

New research shows increase risk of cardiovascular disease for people on low-carbohydrate high-fat diets

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

Also in global health news: Illegal drug trade in E. Africa; Somalia humanitarian crisis; alcohol, IV drug use in Russia; HIV/AIDS in China; FBOs engage in HIV fight

NIH awards Lentigen a SBIR grant for program to generate Hepatitis C Virus-Like Particles

MLL team finds 454 Sequencing technology promising for leukemia genetic characterization

Misuse of blood thinners in dialysis patients reported

NPH acquires an exclusive license from UCLA for a suite of supramolecular nanoparticle technologies

Watson Pharmaceuticals' RAPAFLO demonstrates safety and tolerability in BPH treatment

CORD:USE Cord Blood Bank awarded contract to supply blood units for the NCBI

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

Clinical trial results demonstrate greater efficacy of nilotinib over imatinib for Ph+ CML

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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