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Computer model helps tailor CML treatment to individual patients

Which medicine is best when you are affected by cancer? This can vary from person to person. A new method can help people with a specific type of blood cancer get the best medicine for them.

9 Jan 2025

Developing and refining muscle atrophy models for drug discovery

With the intensification of global population aging, muscle atrophy, characterized by the loss of muscle mass and function, has become an important health issue affecting the elderly. Researchers have widely used various animal and cellular models to gain a deeper understanding of the pathophysiological mechanisms of muscle atrophy and develop effective treatment strategies.

9 Jan 2025

A large-scale tongue cancer organoid library for precision oncology

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis. Surgery combined with chemoradiotherapy is one of the main lines of treatment for high-risk cases of TC.

9 Jan 2025

Could autophagy enhancement slow aging and combat Alzheimer's?

How cellular cleanup systems could hold the key to slowing aging and halting neurodegeneration.

9 Jan 2025

The X factor: Decoding brain aging differences between men and women

Researchers unveil how biological sex influences brain aging, revealing genetic, hormonal, and molecular mechanisms behind cognitive resilience and decline.

9 Jan 2025

New skeletal tissue could revolutionize regenerative medicine and cartilage repair

An international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering.

9 Jan 2025

Can AI chatbots master the science of dietary balance?

Discover how AI chatbots are reshaping weight-loss planning with precision and variety, yet face challenges in balancing macronutrients for optimal health.

9 Jan 2025

New antibiotic shows promise in fighting tuberculosis

A consortium including scientists from the Tropical Institute at LMU University Hospital has demonstrated the effectiveness of a new antibiotic.

9 Jan 2025

Simple green synthesis of silver nanoparticles from goji berries

As the search for sustainability permeates all fields, researchers are turning to a unique organic source for creating antibacterial silver nanoparticles (Ag-NPs) – the humble goji berry.

9 Jan 2025

How stress fuels allergic skin inflammation

Researchers investigate the cellular and molecular mechanisms through which stress exacerbates immunoglobulin E cutaneous allergic inflammation.

9 Jan 2025

Targeting miR-4274 and PEX5 can help overcome radioresistance in colorectal cancer

Colorectal cancer (CRC) is a global health concern, and despite advances in radiotherapy, endogenous radioresistance in CRC patients remains a challenge.

9 Jan 2025

New test predicts lung cancer survival better than current standards

Researchers at the Francis Crick Institute, the UCL Cancer Institute and UCLH have shown that a test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors.

9 Jan 2025

Study links fiber consumption to epigenetic changes with anti-cancer effects

Fiber is well known to be an important part of a healthy diet, yet less than 10% of Americans eat the minimum recommended amount.

9 Jan 2025

Unraveling the push-pull mechanism of neuron migration

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

9 Jan 2025

Unraveling the molecular mechanisms of disease-causing mutations

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a massive study of human protein variants published today in the journal Nature. Unstable proteins are more likely to misfold and degrade, causing them to stop working or accumulate in harmful amounts inside cells.

9 Jan 2025