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New method to create artificial cells that are active and mimic living cells

Protocells - artificial cells - that are active and mimic living cells by moving independently and that are biocompatible and enzymatically active are now possible using an improved method developed by Penn State researchers.

9 Dec 2019

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal of immune enzymes, including CRISPR-Cas systems, that target and destroy viral DNA. But bacteria-killing viruses, also known as phages, have devised their own tools to help them outmaneuver even the most formidable of these bacterial defenses.

9 Dec 2019

NTU scientists find potential route to disabling viruses causing severe respiratory diseases

A team of molecular and structural biologists from Nanyang Technological University, Singapore have found a potential new route to disabling respiratory syncytial virus and human metapneumovirus after elucidating the structure of one of its key components.

9 Dec 2019

New technique holds promise in cancer research and science studies

A new technique reported this week in Science overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.

8 Dec 2019

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

6 Dec 2019

Manuka honey fights infection in surgical dressings

And now, Manuka honey is proving a gamechanger in the fight against extremely drug-resistant infections, according to a new study published in the journal Frontiers.

5 Dec 2019

Cancer patients receiving common heart drugs have less heart damage from cancer therapy

Cancer patients receiving common heart drugs have less heart damage from cancer therapy, according to research presented today at EuroEcho 2019, a scientific congress of the European Society of Cardiology.

4 Dec 2019

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

LUNAC Therapeutics, a UK based drug discovery company focused on the identification and development of advanced anticoagulants with minimal bleeding risk, today announced that, along with the Medicines Discovery Catapult and the University of Leeds, it has been awarded £3.14M funding under Innovate UK’s Biomedical Catalyst program.

4 Dec 2019

Why some sperm swim in circles – it’s a protein defect

A new study published in the journal PNAS shows that some sperm cannot swim straight because they lack a protein called VSP. This motility defect seriously impacts the rates of successful fertilization. In addition, VSP is also found to regulate the amount of calcium that enters the flagellum, the whiplike organelle that propels the sperm towards the waiting ovum or egg. This important discovery may help treat infertility more effectively.

3 Dec 2019

New computational method can help predict and design allosteric functions in proteins

Called the "second secret of life", allostery is one of the most fundamental processes of biology and has been a central focus among scientists across the life sciences spectrum, from fundamental biology to drug development.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

Scientists uncover functions of mysterious organelles in stress response

Stress is a normal response to physical and emotional stimuli, particularly when people face changes in their lives. Though it’s a normal feeling, long-term stress may lead to a range of health conditions. Though people feel stressed from time to time, not all stress is bad.

1 Dec 2019

New compound may enhance dengue vaccine efficacy by simulating amino acid deficiency

A new study published in the journal Science Signaling on November 26, 2019, describes a mouse experiment, in which the immune response to the dengue vaccine was boosted when the mice were first given halofuginone, a plant compound that is well known to herbalists.

27 Nov 2019

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments.

26 Nov 2019

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows.

26 Nov 2019

New method for correcting hypoxic conditions of the central nervous system

Hypoxia is a key factor that accompanies most brain pathologies, including ischemia and neurodegenerative diseases.

26 Nov 2019

Short-term visit to severely polluted city can be detrimental to one's health, study shows

A new study by researchers at UCLA shows that even a short-term visit to a severely polluted city can be detrimental to one's health.

25 Nov 2019

Researchers identify a promising drug pair to attack deadly childhood brain cancers

Researchers have devised a new plan of attack against a group of deadly childhood brain cancers collectively called diffuse midline gliomas, including diffuse intrinsic pontine glioma, thalamic glioma and spinal cord glioma.

20 Nov 2019

New guidance can help avoid unacceptable risks to users of new products containing enzymes

Enzymes bring significant benefits to laundry and cleaning products, including improved cleaning efficiencies. An updated publication from the American Cleaning Institute provides a framework for consumer product manufacturers to develop appropriate risk management strategies to avoid unacceptable risks to the users of new products containing enzymes.

20 Nov 2019

Six ways physicians can help optimize reproductive health in women with epilepsy

Worldwide, more than 15 million women of childbearing age have epilepsy. Each year about 600,000 of them become pregnant.

20 Nov 2019

Enzyme News and Research

New method to create artificial cells that are active and mimic living cells

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

NTU scientists find potential route to disabling viruses causing severe respiratory diseases

New technique holds promise in cancer research and science studies

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Manuka honey fights infection in surgical dressings

Cancer patients receiving common heart drugs have less heart damage from cancer therapy

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

Why some sperm swim in circles – it’s a protein defect

New computational method can help predict and design allosteric functions in proteins

Key component of immune response is activated by short RNAs, shows study

Scientists uncover functions of mysterious organelles in stress response

New compound may enhance dengue vaccine efficacy by simulating amino acid deficiency

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

New method for correcting hypoxic conditions of the central nervous system

Short-term visit to severely polluted city can be detrimental to one's health, study shows

Researchers identify a promising drug pair to attack deadly childhood brain cancers

New guidance can help avoid unacceptable risks to users of new products containing enzymes

Six ways physicians can help optimize reproductive health in women with epilepsy

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo