Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

University of Sydney hosts emerging infectious diseases and biosecurity conference

The latest research to combat emerging infectious diseases threatening Australia is being presented at the Sydney Institute of Emerging Infectious Diseases and Biosecurity Conference at the University of Sydney today.

19 May 2010

BBSRC, EPSRC fund £1.5M for synthetic biology projects under EuroSYNBIO Programme

Four new projects, announced today, will develop biological methods that offer a new approach to antibiotic production, power generation for extremely small mechanical components, new classes of medicines and innovative techniques to study cell biology.

19 May 2010

Antibiotics have significant resistance effects on individual patients in primary care

Antibiotics prescribed in primary care make a considerable contribution to the problem of antimicrobial resistance, both in individual patients and the population as a whole, according to research from the University of Bristol published in this week’s BMJ.

18 May 2010

KaloBios Pharmaceuticals' KB001 promising in prevention of serious lung infection

The data from the initial clinical studies with KB001, a novel antibody fragment against PcrV on Pseudomonas aeruginosa (Pa) bioengineered by KaloBios Pharmaceuticals, Inc. and partnered with sanofi pasteur, demonstrated promising therapeutic activity in the prevention of serious lung infection in mechanically ventilated patients colonized with the bacterium and in limiting potentially damaging inflammation in patients with cystic fibrosis, where Pa plays an important role in the disease.

18 May 2010

Asolva adds infection surveillance tool package to Medici system

Asolva, a leading provider of healthcare data analytics and reporting systems, has added a package of infection surveillance tools to Medici, its clinical information management system. The package will assist pharmacists, physicians and other infection preventionists in tracking and maximizing their antimicrobial stewardship programs.

18 May 2010

Final data from Open-Label studies of Cinryze in patients with HAE now available

ViroPharma Incorporated today announced the availability of final data from Open-Label studies of Cinryze (C1 Esterase Inhibitor [Human]) in preventing and treating attacks of hereditary angioedema on the U.S. National Institutes of Health's online clinical trial registry, www.clinicaltrials.gov.

18 May 2010

Mpex Pharmaceuticals presents Phase 2b trial results of Aeroquin for cystic fibrosis at ATS Annual Meeting

Mpex Pharmaceuticals, Inc. today announced the presentation of data from its Phase 2b clinical trial with Aeroquin™ (a proprietary aerosol formulation of levofloxacin, MP-376) in cystic fibrosis (CF) at the American Thoracic Society (ATS) Annual Meeting in New Orleans.

17 May 2010

Treatment with MP-376 reduces P. aeruginosa in CF patients: Research

A new possible treatment to treat P. aeruginosa in cystic fibrosis patients appears to be promising, according to research to be presented at the ATS 2010 International Conference in New Orleans.

17 May 2010

Johns Hopkins Children's Center neonatologist joins NQF HIT advisory committee

Johns Hopkins Children's Center neonatologist Christoph Lehmann, M.D., has joined the nation's leading watchdog organization on health-care quality, the National Quality Forum (NQF), as a member of its newly formed Health Information Technology (HIT) advisory committee.

14 May 2010

NovaBay first-quarter net loss increases to $1.6 million

NovaBay Pharmaceuticals, Inc., a clinical stage biotechnology company developing first-in-class, anti-infective compounds for the treatment and prevention of antibiotic-resistant infections, today reported financial results for the first quarter of 2010.

12 May 2010

EntreMed adds DF/HCC hospitals to Phase 2 study of ENMD-2076 for platinum resistant ovarian cancer

EntreMed, Inc., today announced the addition of Dana Farber/Harvard Cancer Center (DF/HCC) to the Phase 2 multi-center study entitled "A Phase 2 Study of Oral ENMD-2076 Administered to Patients with Platinum Resistant Ovarian Cancer." Ursula Matulonis, M.D., Associate Professor of Medicine, Dana-Farber Cancer Institute and Harvard Medical School, will serve as principal investigator.

11 May 2010

China Pharma first-quarter revenue up 16% to $15.1 million

China Pharma Holdings, Inc., a leading fully-integrated specialty pharmaceuticals company in China, today announced financial results for the first quarter ended March 31, 2010.

11 May 2010

CrystalGenomics completes European Phase I SAD study of CG400549 antibiotic candidate

CrystalGenomics, Inc., a novel drug R&D company announced today that the Phase I SAD (Single Ascending Dose) study for its novel antibiotic candidate, CG400549, has been successfully completed in Europe.

11 May 2010

Munich researchers develop automated minilab to identify antibiotic residues in milk

No one wants antibiotic residues in their milk. But antibiotics are sometimes used even in the dairy barn. The routine tests conducted nowadays take hours to produce a result and do not test for all of the typical antibiotics. This gap can now be closed, thanks to a fully automated minilab developed by scientists from the TUM in cooperation with the LMU Muenchen and gwk Praezisionstechnik GmbH.

7 May 2010

CU-Boulder develops inhalable vaccine for measles prevention

A team of researchers led by the University of Colorado at Boulder believe a dry powder, inhalable vaccine developed for measles prevention and slated for human clinical trials later this year in India will lead to other inhalable, inexpensive vaccines for illnesses ranging from tuberculosis to cervical cancer.

6 May 2010

Intercell to acquire Cytos' platform technology for monoclonal antibody discovery

Intercell AG today announced that it has signed an agreement with Cytos Biotechnology Ltd. to acquire Cytos' platform technology for monoclonal antibody discovery. The technology is based on expression cloning of monoclonal antibodies from human B-cells and enables the identification of anti-infective antibodies to prevent and treat infectious diseases.

6 May 2010

Increase in antibiotic resistance found in soil microbes

A team of scientists in the United Kingdom and the Netherlands are reporting disturbing evidence that soil microbes have become progressively more resistant to antibiotics over the last 60 years. Surprisingly, this trend continues despite apparent more stringent rules on use of antibiotics in medicine and agriculture, and improved sewage treatment technology that broadly improves water quality in surrounding environments.

6 May 2010

New combination eye drops effective in treating bacterial keratitis

Scientists are reporting development of a potential new way of enabling patients with bacterial keratitis to stick with the extraordinarily intensive treatment needed for this potentially blinding eye infection.

6 May 2010

Aradigm receives FDA IND approval for inhaled liposomal ciprofloxacin

Aradigm Corporation today announced it received clearance from the U.S. Food and Drug Administration (FDA) for its inhaled liposomal ciprofloxacin Investigational New Drug (IND) application. The first trial planned under this IND is a Phase 1/2a, multicenter study designed to evaluate the pharmacokinetics, safety, and tolerability of once-daily administration of 150 mg (3 mL) of Ciprofloxacin for Inhalation (CFI, ARD-3100) in pediatric patients with cystic fibrosis (CF) who have a history of chronic Pseudomonas aeruginosa lung infection.

5 May 2010

Pay-for-performance may create unintended financial incentives for doctors to discriminate against obese patients

Pay-for-performance reimbursement models may create unintended financial incentives for doctors to discriminate against obese patients, measuring a patient's waist circumference may be more effective in predicting surgical outcomes than the more traditional body mass index measure, and childhood obesity doubles the risk of developing colon cancer, according to data being presented at Digestive Disease Week- 2010.

5 May 2010

Antibiotic News and Research

Further Reading

University of Sydney hosts emerging infectious diseases and biosecurity conference

BBSRC, EPSRC fund £1.5M for synthetic biology projects under EuroSYNBIO Programme

Antibiotics have significant resistance effects on individual patients in primary care

KaloBios Pharmaceuticals' KB001 promising in prevention of serious lung infection

Asolva adds infection surveillance tool package to Medici system

Final data from Open-Label studies of Cinryze in patients with HAE now available

Mpex Pharmaceuticals presents Phase 2b trial results of Aeroquin for cystic fibrosis at ATS Annual Meeting

Treatment with MP-376 reduces P. aeruginosa in CF patients: Research

Johns Hopkins Children's Center neonatologist joins NQF HIT advisory committee

NovaBay first-quarter net loss increases to $1.6 million

EntreMed adds DF/HCC hospitals to Phase 2 study of ENMD-2076 for platinum resistant ovarian cancer

China Pharma first-quarter revenue up 16% to $15.1 million

CrystalGenomics completes European Phase I SAD study of CG400549 antibiotic candidate

Munich researchers develop automated minilab to identify antibiotic residues in milk

CU-Boulder develops inhalable vaccine for measles prevention

Intercell to acquire Cytos' platform technology for monoclonal antibody discovery

Increase in antibiotic resistance found in soil microbes

New combination eye drops effective in treating bacterial keratitis

Aradigm receives FDA IND approval for inhaled liposomal ciprofloxacin

Pay-for-performance may create unintended financial incentives for doctors to discriminate against obese patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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