ACE2 News and Research

RSS

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

A recent study posted to the bioRxiv* preprint server demonstrated that the latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages evade immunity imparted by the prior subvariants.

5 May 2022

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

In a recent study published in the journal Cell, researchers investigated distinguishing virological characteristics of Omicron sub-variant BA.2.

3 May 2022

Pets living in households with COVID-19 are high likely to seroconvert and become ill

In a recent study published in the journal Emerging Infectious Diseases, researchers investigated whether pet dogs and cats in the households of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected humans were at risk of infection.

3 May 2022

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

A recent study under review at Nature Portfolio and posted to the Research Square* preprint server depicted how cellular nucleic acid-binding protein (CNBP) inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 May 2022

Study explores SARS-CoV-2 RNA genome's functional interactions with host cell

In a new study, a worldwide map of the SARS-CoV-2 genome-associated host proteins was developed by a team of researchers using the identification of RNA-binding protein by MS (ChIRP-MS) technique.

3 May 2022

Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Researchers demonstrated that plasma levels of leucine-rich repeat-containing 15 are a strong indicator of the severity of COVID-19 in patients with end-stage kidney disease.

3 May 2022

Precision cut slice lung model to study early host viral pathogenesis of SARS-CoV-2 infection

Researchers applied their previously developed precision-cut lung slice model to study the initial events in SARS-CoV-2 pathogenicity in humans.

3 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Study reveals Omicron sub-lineages BA.4 and BA.5 escape neutralizing antibodies elicited in response to BA.1 infection

Researchers evaluated whether neutralizing immunity elicited against Omicron sub-variant BA.1 in unvaccinated and vaccinated individuals adequately protected against infection by Omicron sub-variants, BA.4 and BA.5.

3 May 2022

Infectivity of SARS-CoV-2 Omicron variant in the intestinal tract

Researchers assessed the infectivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant in the intestinal tract.

3 May 2022

Features of SARS-CoV-2 Omicron BA.2 sublineage spike protein

Researchers assessed the traits of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 sublineage spike (S) protein.

3 May 2022

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

A new study published in the journal Gastroenterology used upper and lower gastrointestinal endoscopy to assess whether gut antigen persistence leads to post-acute COVID-19 in patients with or without post-acute COVID-19 symptoms.

3 May 2022

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

Researchers evaluated the importance of the P681 residue within the furin cleavage site of SARS-CoV-2 spike protein in determining the fusogenicity and syncytia formation ability of SARS-CoV-2 strains.

2 May 2022

The generation of SARS-CoV-2 virus-like particles in insect cells

Researchers have reported the development of a promising COVID-19 vaccine candidate which is based on SARS-CoV-2 VLPs, derived from the co-expression of the spike, membrane, and envelope structural proteins in the baculovirus expression system.

2 May 2022

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

A recent research paper posted to the bioRxiv* preprint server demonstrated that a cocktail of two synergetic antibodies extensively neutralized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including Omicron BA.1 and BA.2.

1 May 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

A new study published in Marine Drugs evaluated the inhibitory effect of three polysaccharides, crude polysaccharide from Hizikia fusiforme (CPHF), crude polysaccharide from Sargassum horneri (CPSH), and crude polysaccharide from abalone viscera (CPAV) on the propagation of SARS-CoV-2 in vitro.

28 Apr 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

Green tea catechin as pan-coronavirus attachment inhibitor

In a recent study posted to the Research Square* preprint server, researchers assessed the impact of green tea catechin epigallocatechin gallate (EGCG) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2022

ACE2 News and Research

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

Pets living in households with COVID-19 are high likely to seroconvert and become ill

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

Study explores SARS-CoV-2 RNA genome's functional interactions with host cell

Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Precision cut slice lung model to study early host viral pathogenesis of SARS-CoV-2 infection

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Study reveals Omicron sub-lineages BA.4 and BA.5 escape neutralizing antibodies elicited in response to BA.1 infection

Infectivity of SARS-CoV-2 Omicron variant in the intestinal tract

Features of SARS-CoV-2 Omicron BA.2 sublineage spike protein

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

The generation of SARS-CoV-2 virus-like particles in insect cells

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Green tea catechin as pan-coronavirus attachment inhibitor

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News