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Pain is not a symptom of arthritis, pain causes arthritis

Pain is more than a symptom of osteoarthritis, it is an inherent and damaging part of the disease itself, according to a study published today in journal Arthritis and Rheumatism.

29 Sep 2008

Medulloblastoma in children - two studies find clues to treatment

Medulloblastoma is one of the most common and most malignant brain tumours among children and teenagers. These tumours grow very rapidly, and fifty percent of patients in the long term die from the condition. The details of the processes that lead to the growth of these tumours have remained unknown until now.

12 Aug 2008

Statins have unexpected effect on pool of powerful brain cells

Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.

3 Jul 2008

New insight into role of statins in dementia

3 Jul 2008

Neuroscientists pinpoint how neural activity boosts blood flow to the brain

New research from Harvard University neuroscientists has pinpointed exactly how neural activity boosts blood flow to the brain. The finding has important implications for our understanding of common brain imaging techniques such as fMRI, which uses blood flow in the brain as a proxy for neural activity.

26 Jun 2008

Discovery of mechanism of action of antibiotic able to reduce neuronal cell death in brain

Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant gliomas.

11 May 2008

Leaky blood vessels open up nerve cells to toxic assault In Lou Gehrig's disease

Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience.

7 Apr 2008

Researchers publish MRI images of genes in action in the living brain

Biologists have just confirmed what poets have known for centuries: eyes really are windows of the soul—or at least of the brain.

1 Apr 2008

New brain cells implicated in machinery of cannabinoid signaling

The researchers said their findings could aid in development of treatments for cannabinoid drug abuse. Also, because so-called "endocannabinoids" produced by brain cells are involved in the neural machinery of pain perception and learning and memory, the findings could help in understanding those processes, said the researchers.

28 Mar 2008

Neural progenitor cells as reservoirs for HIV in the brain

Impaired brain function is a prominent and still unsolved problem in AIDS.

6 Mar 2008

Human stem cells aid stroke recovery in rats

Neural cells derived from human embryonic stem cells helped repair stroke-related damage in the brains of rats and led to improvements in their physical abilities, according to a new study by researchers at the Stanford University School of Medicine.

20 Feb 2008

Targeting astrocytes slows progression of Lou Gehrig's disease

In what the researchers say could be promising news in the quest to find a therapy to slow the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, scientists at the University of California, San Diego (UCSD) School of Medicine have shown that targeting neuronal support cells called astrocytes sharply slows disease progression in mice.

4 Feb 2008

Epilepsy and brain pathology linked together by the protein ADK

The brain of individuals who suffer from epilepsy is characterized by astrogliosis, a brain pathology evidenced by a complex series of changes in the morphology and function of brain cells known as astrocytes.

3 Jan 2008

Immune system may target some brain synapses

A baby's brain has a lot of work to do, growing more neurons and connections.

14 Dec 2007

New study finds blood-spinal cord barrier compromised in mice with ALS

The blood-spinal cord barrier is functionally impaired in areas of motor neuron damage in mice modeling amyotrophic lateral sclerosis (ALS), report researchers at the University of South Florida Center for Aging and Brain Repair.

21 Nov 2007

Neurofibromatosis 1 gene drives pivotal decision in early brain development

A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers at Washington University School of Medicine in St. Louis have found.

14 Nov 2007

Feline virus, antiviral drug studied to understand drug resistance

Researchers at Ohio State will spend the next two years testing their theories about just how an AIDS-like virus in cats is able to resist the powerful medicines that are thrown against it.

10 Oct 2007

Stem-cell therapy opens new avenue of research against Huntington's disease

Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington's disease – a fatal disorder for which there is currently no cure or even a treatment to slow the disease.

26 Sep 2007

Viewing dye-packed vesicles causes them to explode

It's a long-standing question: Can just the act of observing an experiment affect the results, According to a new study by Rockefeller University scientists, if the experiment uses a fluorescent dye called acridine orange, the answer is a resounding yes."

25 Sep 2007

New discovery for Fragile X Syndrome

An important finding has been made by McMaster researchers about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects approximately one in 4,000 males and one in 6,000 females.

11 Sep 2007