Cell Signaling News and Research

RSS

Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Researchers uncover two factors that play crucial role in chronic autoimmune disorders

Researchers from Schepens Eye Research Institute of Massachusetts Eye and Ear have uncovered two factors responsible for the chronic, lifelong nature of autoimmune disorders, which tend to "flare up" intermittently in affected patients.

4 Jan 2017

Genetic mutation may increase susceptibility to cytomegalovirus infection

Experimenting with human cells and mice, Johns Hopkins researchers have found that a genetic mutation that alters a protein called NOD1 may increase susceptibility to human cytomegalovirus (CMV) infection.

20 Dec 2016

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer.

20 Dec 2016

Study identifies four previously unknown genetic risk locations for primary sclerosing cholangitis

A study of unprecedented scale has led researchers to identify four previously unknown genetic risk locations for primary sclerosing cholangitis, a liver disease that lacks effective medical therapy.

20 Dec 2016

New graphene-based method may help visualize electrical signaling networks in heart and brain cells

Scientists have enlisted the exotic properties of graphene, a one-atom-thick layer of carbon, to function like the film of an incredibly sensitive camera system in visually mapping tiny electric fields in a liquid.

16 Dec 2016

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Nearly every cell in the human body has one or more protrusive structures called cilia or flagella.

7 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

Conventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors' recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered.

24 Nov 2016

Researchers uncover new clues that may help combat leukemia and other B cell cancers

When B lymphocytes (a type of white blood cell in the immune system geared for fighting diseases) turn cancerous, they become part of the problem, and need to be eliminated.

22 Nov 2016

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Virginia Tech scientists have developed a new cancer drug that uses gold nanoparticles created by the biotech firm CytImmune Sciences to deliver paclitaxel — a commonly used chemotherapy drug directly to a tumor.

14 Nov 2016

Scientists investigate role of mitochondria in Alzheimer's disease pathology

On Nov. 25, 1901, a 51-year-old woman is admitted to a hospital in Frankfurt, Germany, displaying a bizarre constellation of symptoms.

8 Nov 2016

Scientists unravel viral molecular strategies to counter mammalian immune system

As mammals evolve, so do mammalian viruses. In doing so, they develop creative and effective ways to counter and evade the antiviral responses of their mammal hosts' immune systems.

7 Nov 2016

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

National Institutes of Health researchers have identified a novel role for a gene known as heat shock protein 60 (Hsp60), finding that it is critical in tissue regeneration and wound healing.

27 Oct 2016

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

The study began by taking the medical history of 11 children, all of whom had a disorder due to mycobacteria infections, as the basis. All were discovered to have the same phenotype with the same mutation, which was located in the interferon-gamma (IFNGR) receptor, so the group began to explore what was causing this dysfunction.

27 Oct 2016

Research could lead to new therapeutic targets for suppressing tumor growth

A new study has identified a mechanism used by tumors to recruit stem cells from bone and convert them into cancer-associated fibroblasts (CAFs) that facilitate tumor progression.

21 Oct 2016

Study unravels how caloric restriction provides beneficial effects to the brain

Studies of different animal species suggest a link between eating less and living longer, but the molecular mechanisms by which caloric restriction affords protection against disease and extends longevity are not well understood.

19 Oct 2016

NYU Langone's cancer researcher receives Outstanding Investigator Award from NCI

Throughout her distinguished career, cancer researcher Dafna Bar-Sagi, PhD, has made fundamental contributions to the understanding of the mechanisms that drive the disease.

18 Oct 2016

Research reveals role of endoglin in shaping blood and cardiac cell fate during early development

New research from the University of Minnesota reveals endoglin as a critical factor in determining the fate of early undifferentiated cells during development.

7 Oct 2016

TSRI scientists shed light on molecular workings of MS drug

A study by scientists at The Scripps Research Institute has helped to de-mystify the molecular workings of the multiple sclerosis (MS) drug Tecfidera. The drug is the most widely prescribed pill-based therapy for MS, but its biological mechanism remains mysterious.

21 Sep 2016

Researchers reveal presence of toxic protein aggregates in the human brain

The following factors facilitate the formation of putatively toxic structures in the neuronal nuclei of Alzheimer's patients.

16 Sep 2016

Cell Signaling News and Research

Further Reading

Researchers uncover two factors that play crucial role in chronic autoimmune disorders

Genetic mutation may increase susceptibility to cytomegalovirus infection

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Study identifies four previously unknown genetic risk locations for primary sclerosing cholangitis

New graphene-based method may help visualize electrical signaling networks in heart and brain cells

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Research unlocks potential new therapies for inflammatory diseases

Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

Researchers uncover new clues that may help combat leukemia and other B cell cancers

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Scientists investigate role of mitochondria in Alzheimer's disease pathology

Scientists unravel viral molecular strategies to counter mammalian immune system

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

Research could lead to new therapeutic targets for suppressing tumor growth

Study unravels how caloric restriction provides beneficial effects to the brain

NYU Langone's cancer researcher receives Outstanding Investigator Award from NCI

Research reveals role of endoglin in shaping blood and cardiac cell fate during early development

TSRI scientists shed light on molecular workings of MS drug

Researchers reveal presence of toxic protein aggregates in the human brain

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo