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The impact of cold agglutinin syndrome on clinical presentations in COVID-19

Researchers presented two cases to highlight the impact of cold agglutinin syndrome on clinical presentations in COVID-19.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

Study highlights the urgent need to evaluate deficiencies in the energy balance model for the prevention and treatment of obesity

In a new study, researchers highlighted the urgent need to substitute highly processed carbohydrates with minimally processed carbohydrates or healthy fats to cease the obesity pandemic that continues relentlessly.

2 Aug 2022

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

A new research paper was published in Aging ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) Volume 14, Issue 13, entitled, "Age-related neuroendocrine, cognitive, and behavioral co-morbidities are promoted by HIV-1 Tat expression in male mice."

29 Jul 2022

UK study finds over 100 symptoms of long COVID in non-hospitalized adults

In a new study, researchers determined symptoms and risk factors present beyond 12 weeks in non-hospitalized adults with confirmed SARS-CoV-2 infection.

27 Jul 2022

How COVID-19 affects the brain microvasculature

A recent study discusses the effects of COVID-19 on the brain microvascular system.

25 Jul 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application (MAA) to the European Medicines Agency (EMA) for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 21 Jul 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application to the European Medicines Agency for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 19 Jul 2022

Survey explores the experiences of individuals with long COVID

Researchers explored the experiences of individuals with post-acute sequelae of COVID-19, also known as long COVID.

18 Jul 2022

Evidence for a specific anti-inflammatory metabolic signature in long-COVID

A recent research paper posted to the medRxiv* preprint server illustrated anti-inflammatory and hypo-metabolic fingerprints in long coronavirus disease (COVID) syndrome (LCS) using pan-omics plasma assessments.

15 Jul 2022

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage.

12 Jul 2022

Low doses of a less commonly used drug may be a better treatment option for gout

Gout occurs when urate crystals accumulate in the joints, and xanthine oxidase inhibitors such as febuxostat are a mainstay of therapy to help reduce blood urate levels in affected patients.

7 Jul 2022

Targeting C5a/C5aR1 signaling ameliorates COVID-19 immunopathology

A new study investigated the role of complement component 5a (C5a) and its receptor (C5a receptor type 1, C5aR1) in the pathophysiology of COVID-19.

6 Jul 2022

What causes insomnia and how to treat it?

A new study evaluates the symptoms of insomnia and its treatment as reported by patients in primary care settings.

5 Jul 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Evaluating post-acute sequelae of COVID-19 using cardiopulmonary exercise testing

Researchers demonstrated reduced exercise capacity due to persistent cardiopulmonary symptoms among COVID-19 survivors hospitalized for acute infection and those having long COVID.

20 Jun 2022

Elevated Th17 cells associated with increased risk of critical COVID

In a recent article published in the European Journal of Internal Medicine, researchers in France indicated that T cell immune reaction correlates possibly with the chance of critical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among hospitalized patients.

14 Jun 2022

A comparison of SARS-CoV-2 and influenza cytokine storms

In a recent study published in the Journal of Interferon & Cytokine Research, researchers compared the cytokine storms of pandemic influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

9 Jun 2022

Walking for exercise could help people with knee osteoarthritis to prevent frequent knee pain

In a study published in Arthritis & Rheumatology that included individuals aged 50 years and older who had knee osteoarthritis, those who walking for exercise were less likely to develop frequent knee pain.

8 Jun 2022

Pathophysiology News and Research

The impact of cold agglutinin syndrome on clinical presentations in COVID-19

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

Study highlights the urgent need to evaluate deficiencies in the energy balance model for the prevention and treatment of obesity

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

UK study finds over 100 symptoms of long COVID in non-hospitalized adults

How COVID-19 affects the brain microvasculature

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

Survey explores the experiences of individuals with long COVID

Evidence for a specific anti-inflammatory metabolic signature in long-COVID

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

Low doses of a less commonly used drug may be a better treatment option for gout

Targeting C5a/C5aR1 signaling ameliorates COVID-19 immunopathology

What causes insomnia and how to treat it?

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Evaluating post-acute sequelae of COVID-19 using cardiopulmonary exercise testing

Elevated Th17 cells associated with increased risk of critical COVID

A comparison of SARS-CoV-2 and influenza cytokine storms

Walking for exercise could help people with knee osteoarthritis to prevent frequent knee pain

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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