Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

FDA proposes to change regulation of ECT treatment

For decades, people with severe depression, bipolar disorder, and other major mental health conditions have gotten help from the treatment known as ECT, when nothing else helped them.

24 Mar 2016

Warning of increased mortality risk for PD patients taking antipsychotics

Researchers have found a more than twofold increase in the risk of death among patients with Parkinson's disease who take antipsychotics, particularly typical antipsychotics.

23 Mar 2016

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

At least half of Parkinson's disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.

21 Mar 2016

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe.

15 Mar 2016

Exercise programme reduces symptoms among young adults with first-episode psychosis

An exercise programme devised by researchers at the University of Manchester has dramatically reduced symptoms among young people with first-episode psychosis.

15 Mar 2016

Studies raise hope for new treatments, preventive approaches for schizophrenia

Emerging evidence on the development, "prodromal" characteristics, and long-term course of schizophrenia provide reasons for optimism for developing new treatments and preventive approaches for this devastating disorder, according to the special March/April issue of Harvard Review of Psychiatry.

11 Mar 2016

Study finds strong link between postpartum disorder and suicide risk in new mothers

Over a period spanning four decades, a total of eight Danish women committed suicide within a year of being diagnosed with a birth-related psychiatric disorder, including severe episodes of postpartum depression or psychosis.

7 Mar 2016

Early intervention treatment at home, school can help young people with psychotic-like symptoms

Young people with mental problems - especially those with psychotic-like symptoms - should receive help as early as possible and in their own environment. This was the conclusion of a joint study of the University of Helsinki, the Helsinki University Hospital Department of Psychiatry and the National Institute for Health and Welfare, Finland.

19 Feb 2016

Antibiotics may be linked to delirium and other brain problems

Antibiotics may be linked to a serious disruption in brain function, called delirium, and other brain problems, more than previously thought, according to a "Views and Reviews" article published in the February 17, 2016, online issue of Neurology, a medical journal of the American Academy of Neurology.

18 Feb 2016

AKT1 gene moderates mind-altering effects of smoking cannabis in young people

Researchers at the University of Exeter and UCL (University College London) have identified a gene which can be used to predict how susceptible a young person is to the mind-altering effects of smoking cannabis. The finding could help identify otherwise healthy users who are most at risk of developing psychosis.

17 Feb 2016

Coordinated specialty care more cost-effective for young people with first episode psychosis

New analysis from a mental health care study shows that "coordinated specialty care" (CSC) for young people with first episode psychosis is more cost-effective than typical community care. Cost-effectiveness analysis in health care is a way to compare the costs and benefits of two or more treatment options.

2 Feb 2016

Frequent traumatic experiences throughout infancy increase risk of psychosis during adulthood

A research carried out with participation of the University of Granada proves that suffering repeated traumatic experiences throughout infancy and adolescence multiplies by 7 the risk of suffering psychosis during adulthood.

1 Feb 2016

Research offers novel insights into root causes of schizophrenia

Schizophrenia is a mysterious and devastating disorder that afflicts one percent of the adult population worldwide. Its symptoms — hallucinations, emotional withdrawal, and cognitive impairment — are chronic and typically emerge just as individuals are entering adulthood. Today's medications treat just one of these symptoms (psychosis); treatments for the underlying disease and its many other symptoms have been hard to develop, because no one really understands what causes the disorder.

31 Jan 2016

Citalopram of limited use for dementia-associated agitation

The use of citalopram for the treatment of agitation in Alzheimer’s disease may be limited to a small group of people with moderate agitation and low levels of cognitive impairment, study findings suggest.

19 Jan 2016

Diseases that cause skin-related problems can also trigger serious neurological conditions

Diseases such as lupus that cause rashes and other skin problems also can trigger migraine headaches, strokes and other serious neurological conditions, according to an article by Loyola University Medical Center physicians.

16 Dec 2015

Gene variant linked to psychotic symptoms, cognitive impairment in people with bipolar disorder identified

Researchers at Karolinska Institutet, and the Sahlgrenska Academy at Gothenburg University in Sweden have identified a gene variant linked to psychotic symptoms and cognitive impairment in people with bipolar disorder. The study, which is published in the journal Molecular Psychiatry, describes a possible mechanism for how the gene variant produces clinical symptoms by affecting levels of specific proteins in the brain.

15 Dec 2015

LSD reduces connectivity within human brain networks

LSD is known to cause changes in consciousness, including "ego-dissolution", or a loss of the sense of self. Despite a detailed knowledge of the action of LSD at specific serotonin receptors, it has not been understood how this these pharmacological effects can translate into such a profound effect on consciousness.

11 Dec 2015

Biotypes can identify distinct subgroups of psychosis

Three biomarker-based categories, called biotypes, outperformed traditional diagnoses, such as schizophrenia and bipolar disorder with psychosis, in sorting psychosis cases into distinct subgroups on the basis of brain biology, report researchers funded by the National Institutes of Health.

9 Dec 2015

Groundbreaking study establishes empirical biomarkers to aid in diagnosis, treatment of psychosis

In a groundbreaking study led by UT Southwestern Medical Center, a comprehensive set of empirical biomarkers has been established to aid in diagnosis and treatment of psychosis.

9 Dec 2015

UGA researchers identify biological markers for mental disorders

A team of researchers led by faculty at the University of Georgia has identified a number of biological markers that make it possible to classify mental disorders with greater precision. Their findings, published today in the American Journal of Psychiatry, may one day lead to improved diagnostics and treatments for those suffering from mental illness.

9 Dec 2015

Psychosis News and Research

Further Reading

FDA proposes to change regulation of ECT treatment

Warning of increased mortality risk for PD patients taking antipsychotics

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Exercise programme reduces symptoms among young adults with first-episode psychosis

Studies raise hope for new treatments, preventive approaches for schizophrenia

Study finds strong link between postpartum disorder and suicide risk in new mothers

Early intervention treatment at home, school can help young people with psychotic-like symptoms

Antibiotics may be linked to delirium and other brain problems

AKT1 gene moderates mind-altering effects of smoking cannabis in young people

Coordinated specialty care more cost-effective for young people with first episode psychosis

Frequent traumatic experiences throughout infancy increase risk of psychosis during adulthood

Research offers novel insights into root causes of schizophrenia

Citalopram of limited use for dementia-associated agitation

Diseases that cause skin-related problems can also trigger serious neurological conditions

Gene variant linked to psychotic symptoms, cognitive impairment in people with bipolar disorder identified

LSD reduces connectivity within human brain networks

Biotypes can identify distinct subgroups of psychosis

Groundbreaking study establishes empirical biomarkers to aid in diagnosis, treatment of psychosis

UGA researchers identify biological markers for mental disorders

Lab Matters host Harriet Gould on building a more connected lab community

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