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World's largest protein connection map reveals cell workings

The human body is comprised of billions of cells. Yet it functions and grows as a single organism, because of trillions of interactions that help various cells recognize and respond to each other via different molecules on their surface or inside the cells. Now, a new study published in the journal Nature in April 2020 describes the first-ever interactome map, to help distinguish healthy interactions and disease-producing ones.

8 Apr 2020

World's largest map of protein connections holds clues to health and disease

Scientists have described the first reference map of interactions between gene-encoded proteins which make up cells.

8 Apr 2020

New technology enables on-demand production of nutrients during space missions

On March 9, 2020, a Dragon cargo spacecraft arrived at the International Space Station carrying dozens of scientific experiments as a part of SpaceX's 20th cargo resupply mission. Now, Dragon heads home. On April 7, it is scheduled to undock from station, bringing samples, hardware and data from completed investigations back to Earth on its return trip.

8 Apr 2020

New insight on mechanism of prions brings hope for treating neurodegenerative diseases

Prions are a class of misfolded proteins that form aggregates called "amyloid fibrils." These aggregates are the main culprit behind severe mammalian neurodegenerative diseases like Alzheimer's.

7 Apr 2020

Clemson study provides insight into role of fungi in early childhood dental health

Although mostly preventable, tooth decay is one of the most common chronic diseases in children worldwide, particularly in developing countries. If left untreated, cavities can be painful and may negatively affect a young child's overall health, development and quality of life.

6 Apr 2020

Two newer types of diabetes medications show heart and kidney benefits

Two newer types of medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

31 Mar 2020

Research reveals important mechanism in the repair of DNA double-strand breaks

Scientists have revealed an important mechanism in the repair of DNA double-strand breaks, according to new research published today in eLife.

24 Mar 2020

New bacteria-killing light-activated coating

A new antimicrobial coating that can be activated by light has been reported by researchers in the journal Nature Communications, in March 2020. The coating can be used to prevent transmission from computer and phone screens and keyboards, the inside of catheters, and breathing tubes. All these are significant routes of healthcare-associated infections (HCAIs).

5 Mar 2020

Michael Hall named winner of 2020 Sjöberg Prize

Michael N. Hall, Ph.D., the National Foundation for Cancer Research's (NFCR) 2017 Szent-Györgyi Prize for Progress in Cancer Research winner, and David Sabatini, M.D., Ph.D., were named winners of the 2020 Sjöberg Prize "for their discovery of the target of rapamycin and the mammalian target of rapamycin, and their roles in the control of cell metabolism and growth."

28 Feb 2020

Researchers explore the role of SLC25A32 in cancer cell proliferation

Oncotarget Volume 11 Issue 8 reported that while it is known that cancer cells require one-carbon and FAD-dependent mitochondrial metabolism to sustain cell proliferation, the role of SLC25A32 in cancer cell growth remains unexplored.

28 Feb 2020

Study identifies novel anti-aging targets

A recent study published in Nature has reported two conserved epigenetic regulators as novel anti-aging targets.

26 Feb 2020

Woman's bladder produces alcohol – a rare medical condition

A 61-year-old woman was set for a liver transplant but was denied due to a high level of alcohol in her system. Her urine contained alcohol, which is unlikely unless someone has consumed large amounts of it.

25 Feb 2020

Amino acids from new torula yeast product are more digestible than fish meal by young pigs

Starting weanling pigs off with the right diet can make all the difference for the health and productivity of the animal.

23 Feb 2020

Scientists make important discovery with implications for people living with AMD

Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness.

20 Feb 2020

Antioxidant in mushrooms may relieve symptoms of pre-eclampsia

Pregnancy hypertension, or Pre-eclampsia, is a complex disorder of pregnancy. Treatment of elevated blood pressure can manage the condition in the mother, but in severe cases delivery is needed, which can present a major problem to the baby if it is born prematurely.

18 Feb 2020

Generating genomes and encoding new abilities into artificial DNA

A new study to be presented at the American Association for the Advancement of Science (AAAS) in February 2020 will report on the generation of the world’s first artificially created bacterial genome using a digital design algorithm along with the synthesis of DNA building blocks on a large scale. This genome takes form by chemical rather than template-based synthesis. The research is published in the journal Proceedings of the National Academy of Sciences.

16 Feb 2020

Unexpected findings could lead to new therapeutic intervention for ALS

A therapeutic intervention for amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, could be on the horizon thanks to unexpected findings by University of Arizona researchers.

11 Feb 2020

The Science Behind the Beer and Brewing Industry

Beer consists primarily of four ingredients; water, malted grain, hops, and yeast. Yet, the analysis of beer and the brewing process has changed dramatically over the last decade. In this interview, Christopher Welch from the Indiana Consortium for Analytical Science and Engineering (ICASE) talks to News-Medical Life Sciences about the new and improving developments in the analytical chemistry of beer and brewing analysis.

From Pittcon 23 Jan 2020

Discovery of metabolic system could lead to new strategies for cancer treatment

Australian researchers have uncovered a metabolic system which could lead to new strategies for therapeutic cancer treatment.

21 Jan 2020

New molecular mechanism can reverse genetic defect responsible for Friedreich's ataxia

Scientists at Tufts University have identified a molecular mechanism that could reverse the genetic defect responsible for Friedreich's ataxia, a neurodegenerative disease that leaves its victims with difficulty walking, a loss of sensation in the arms and legs and impaired speech caused by degeneration of nerve tissue in the spinal cord.

6 Jan 2020