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Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States.

28 Jun 2016

Researchers identify exact origin of 2009 swine H1N1 flu pandemic

The 2009 swine H1N1 flu pandemic — responsible for more than 17,000 deaths worldwide — originated in pigs from a very small region in central Mexico, a research team headed by investigators at the Icahn School of Medicine at Mount Sinai is reporting.

28 Jun 2016

Virus-like elements within human genome linked to development of lupus and Sjogren's syndrome

Researchers at Hospital for Special Surgery have uncovered a potential genetic trigger of systemic autoimmune disease.

28 Jun 2016

Researchers investigate why N14Y, N14K mutations have distinct effects in KID syndrome patients

A team of New York-based researchers has compared the effects of two disease-causing mutations, potentially explaining why patients with the rare genetic disorder keratitis-ichthyosis-deafness (KID) syndrome can experience different sets of symptoms.

28 Jun 2016

New non-invasive method may help treat people with inoperable or hard-to-reach tumors

Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells.

28 Jun 2016

Pain reliever appears to help preserve vision in animal model of retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in a model of severe retinal degeneration, scientists report.

28 Jun 2016

Study pinpoints how PSEN1 gene mutations can cause early onset Alzheimer's disease

A University of Adelaide analysis of genetic mutations which cause early-onset Alzheimer's disease suggests a new focus for research into the causes of the disease.

27 Jun 2016

Scientists discover link between two genes involved in PD and autoimmune diseases

A study publish in the journal CELL indicates that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.

27 Jun 2016

CYP2C19 gene variants undermine clopidogrel stroke prevention

The first look at CYP2C19 mutations in the context of a randomised controlled trial has confirmed suspicions that they affect the efficacy of clopidogrel in patients with acute stroke.

24 Jun 2016

Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

All life on the planet relies, in one way or another, on a process called carbon fixation: the ability of plants, algae and certain bacteria to "pump" carbon dioxide (CO2) from the environment, add solar or other energy and turn it into the sugars that are the required starting point needed for life processes.

24 Jun 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Yale-led study shows how EGFR silences tumor suppressor genes

A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types.

24 Jun 2016

Scientists discover how faulty genetic instructions contribute to development of AML

Scientists have previously identified a series of genetic errors that commonly occur inside cancerous blood cells, but it hasn't been clear exactly how those genetic malfunctions create immature blood cells that overpopulate, crowd out healthy cells and spread in patients with acute myeloid leukemia or AML.

24 Jun 2016

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

The first global mapping of artemisinin resistance has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa.

24 Jun 2016

Genetic testing worthwhile in sudden cardiac death

Genetic testing and family screening help to provide explanations for sudden cardiac death in children and young adults, shows a population-based study.

24 Jun 2016

Major review highlights lack of genetic understanding of Zika virus

A major review of the Zika virus has concluded that further research to understand the nature of the virus is critical to developing antiviral treatments and vaccines.The paper, published in the journal Veterinary Quarterly, considers the breadth of current research and highlights a lack of understanding of the nature of the virus.

23 Jun 2016

Study shows many people may have potential to develop Huntington's disease

More people may have the potential to develop Huntington's disease than previously thought, according to a study published in the June 22, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Jun 2016

Researchers uncover new clues about role of glucosamine in early embryonic development

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early in embryonic development, the babies are exposed to higher levels of glucose in maternal blood.

23 Jun 2016

Researchers find link between clu and genes that cause Parkinson's disease

The fruit fly may help us be less clueless about human muscle development and Parkinson's disease.

22 Jun 2016

Scientists uncover five new genetic causes of bowel cancer

A landmark study has given the most detailed picture yet of the genetics of bowel cancer - the UK's fourth most common cancer.

22 Jun 2016

Mutation News and Research

Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Researchers identify exact origin of 2009 swine H1N1 flu pandemic

Virus-like elements within human genome linked to development of lupus and Sjogren's syndrome

Researchers investigate why N14Y, N14K mutations have distinct effects in KID syndrome patients

New non-invasive method may help treat people with inoperable or hard-to-reach tumors

Pain reliever appears to help preserve vision in animal model of retinal degeneration

Study pinpoints how PSEN1 gene mutations can cause early onset Alzheimer's disease

Scientists discover link between two genes involved in PD and autoimmune diseases

CYP2C19 gene variants undermine clopidogrel stroke prevention

Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

Mutant fruit flies provide insight into origins of Parkinson's disease

Yale-led study shows how EGFR silences tumor suppressor genes

Scientists discover how faulty genetic instructions contribute to development of AML

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

Genetic testing worthwhile in sudden cardiac death

Major review highlights lack of genetic understanding of Zika virus

Study shows many people may have potential to develop Huntington's disease

Researchers uncover new clues about role of glucosamine in early embryonic development

Researchers find link between clu and genes that cause Parkinson's disease

Scientists uncover five new genetic causes of bowel cancer

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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