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Intestinal microbiota necessary for optimum postnatal growth

The intestinal microbiota is necessary to ensure optimum postnatal growth and contributes to determining the size of adult individuals, notably in the event of undernutrition.

22 Feb 2016

KU Leuven scientists improve survival of implanted bone cells

To treat a complicated, non-healing bone defect, surgeons often use an implant with living cells to promote bone repair, but the implanted cells have a small chance of surviving because they are not prepared for a lack of oxygen and nutrients at the fracture site.

19 Feb 2016

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Novartis announced today that the United States Food and Drug Administration has granted Breakthrough Therapy designation to PKC412 (midostaurin). PKC412 (midostaurin) is an investigational treatment for adults with newly-diagnosed AML who are FLT3 mutation-positive, as detected by an FDA-approved test, and who are eligible to receive standard induction and consolidation chemotherapy.

19 Feb 2016

Bariatric surgery prior to TKR is cost-effective option to improve outcomes in severely obese patients

Obesity is not only a risk factor for developing knee arthritis. It is also linked to less favorable outcomes after joint replacement surgery. A study at Hospital for Special Surgery (HSS) in New York City finds that bariatric surgery prior to total knee replacement (TKR) is a cost-effective option to improve outcomes.

19 Feb 2016

High-fat diet can lead to weight gain and health complications

A new study has revealed following a low-carbohydrate, high-fat diet for just eight weeks can lead to rapid weight gain and health complications.

19 Feb 2016

Sustainable surgical follow-up program may be cost-effective in ensuring acceptable outcomes

Each year, hundreds of orthopaedic surgeons travel to developing countries to treat and care for patients. Yet despite the successful completion of many surgical procedures on patients who may not otherwise have access to care, adequate follow-up--so critical to optimal outcomes--is not always available or guaranteed.

18 Feb 2016

Tackling insulin resistance may reduce recurrence after stroke

Giving pioglitazone to stroke survivors with insulin resistance but no overt diabetes reduces their risk of having a recurrent vascular event, shows the randomised Insulin Resistance Intervention after Stroke trial.

18 Feb 2016

Testosterone treatment for older men improves sexual function, walking ability and mood

As men age, their testosterone levels decrease, but prior studies of the effects of administering testosterone to older men have been inconclusive. Now, research shows that testosterone treatment for men over 65 improves sexual function, walking ability and mood, according to a study published in the New England Journal of Medicine by team researchers from the Perelman School of Medicine at the University of Pennsylvania, and twelve other medical centers in the United States, in partnership with the National Institute on Aging.

18 Feb 2016

African Americans with common genetic variants at increased risk for blood clots

New research published online today in Blood, the Journal of the American Society of Hematology (ASH), identifies common genetic variants predominantly found in African Americans that double their risk for blood clots.

18 Feb 2016

Pioglitazone drug may prevent recurrent stroke and heart attacks

Pioglitazone, a drug used for type 2 diabetes, may prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes.

18 Feb 2016

Allo-HSCT Non-Relapse Related Mortality Reduction Revealed

A reduction in the risks of infection- and organ failure-related death has driven an improvement in non-relapse mortality among recipients of allogeneic haematopoietic stem cell transplantation, Japanese research suggests.

17 Feb 2016

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

A study led by scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key player contributing to the maintenance of hematopoietic stem cells (HSCs), blood cell precursors which have the ability to become any type of blood cell in the body.

17 Feb 2016

Green tea compound has high potential as treatment for rheumatoid arthritis

Researchers at Washington State University in Spokane have identified a potential new approach to combating the joint pain, inflammation and tissue damage caused by rheumatoid arthritis.

17 Feb 2016

Physical therapy reduces urinary problems in postmenopausal women with osteoporosis

After menopause, women with osteoporosis struggle more with urinary incontinence than women with healthy bones do. But physical therapy that includes pelvic floor muscle training can produce dramatic improvements, shows a study published online today in Menopause, the journal of The North American Menopause Society.

17 Feb 2016

Study shows male cancer survivors less likely to have children

A study of all Norwegian men born between 1965 and 1985 shows that male cancer survivors are less likely to have children than those without a cancer diagnosis.

17 Feb 2016

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

MemorialCare Health System announced today that it has entered into a joint venture partnership with Fresenius Medical Care North America to operate 15 dialysis clinics in Orange and Los Angeles counties. Thirteen of these clinics are fully operational and two additional clinics are being developed in San Juan Capistrano and Huntington Beach.

17 Feb 2016

Low-dose EOS performs as well as conventional CT scans in assessing limb length, finds HSS study

When a child needs repeated x-rays, exposure to radiation is always a concern for parents. A new study at Hospital for Special Surgery finds that a relatively new imaging system known as EOS, which provides less radiation exposure, performed as well as conventional CT scans in assessing limb length.

16 Feb 2016

UAB research reveals heterogonous population of leukemia stem cells

University of Alabama at Birmingham researchers have found a marker on blood cells that may help the most pressing problem in chronic myelogenous leukemia, or CML, today — an inability to get patients off treatment.

16 Feb 2016

Amgen announces availability of Kyprolis (carfilzomib) in the UK for treatment of relapsed multiple myeloma

Amgen today announced that Kyprolis in combination with lenalidomide and dexamethasone is now available in the UK for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

16 Feb 2016

St. Jude-led scientists explore better ways to use blood-forming stem cells for therapeutic interventions

A team of researchers led by scientists at St. Jude Children's Research Hospital is looking at ways to improve how blood-forming stem cells can be used for therapeutic interventions. The work has uncovered a group of genes that regulate how hematopoietic stem cells start to grow and thrive in mice. The function of many of these genes was previously unknown. Reconstitution of a robust blood-forming system is essential for recovery from many catastrophic diseases as well as from chemotherapy treatments.

16 Feb 2016

Bone News and Research

Intestinal microbiota necessary for optimum postnatal growth

KU Leuven scientists improve survival of implanted bone cells

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Bariatric surgery prior to TKR is cost-effective option to improve outcomes in severely obese patients

High-fat diet can lead to weight gain and health complications

Sustainable surgical follow-up program may be cost-effective in ensuring acceptable outcomes

Tackling insulin resistance may reduce recurrence after stroke

Testosterone treatment for older men improves sexual function, walking ability and mood

African Americans with common genetic variants at increased risk for blood clots

Pioglitazone drug may prevent recurrent stroke and heart attacks

Allo-HSCT Non-Relapse Related Mortality Reduction Revealed

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

Green tea compound has high potential as treatment for rheumatoid arthritis

Physical therapy reduces urinary problems in postmenopausal women with osteoporosis

Study shows male cancer survivors less likely to have children

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

Low-dose EOS performs as well as conventional CT scans in assessing limb length, finds HSS study

UAB research reveals heterogonous population of leukemia stem cells

Amgen announces availability of Kyprolis (carfilzomib) in the UK for treatment of relapsed multiple myeloma

St. Jude-led scientists explore better ways to use blood-forming stem cells for therapeutic interventions

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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