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Survey confirms low BPA exposure levels in food packaging

Today's supermarket survey of a handful of canned food products by the Breast Cancer Fund offers further confirmation that only a very small amount of bisphenol A (BPA) is found in food packaging, and those levels are well within the safety recommendations of government agencies.

21 Sep 2011

Maternal exposures to BPA are not transmitted to fetus: FDA study

The North American Metal Packaging Alliance, Inc. (NAMPA) applauds the publication of yet another government-funded and conducted study that provides reassuring evidence that bisphenol A (BPA) is not harmful to infants, children, or adults.

21 Sep 2011

Niiki Pharma announces positive data from ongoing trial of novel anti-cancer agent NKP-1339

Niiki Pharma Inc. announced interim results from the ongoing Phase I clinical trial of its lead product, NKP-1339. NKP-1339 is a first-in-class transferrin targeted small molecule that down-regulates GRP78, a key regulator of mis-folded protein processing and a tumor survival factor.

20 Sep 2011

U-M Professor to review data from three prominent studies on heart failure

Roughly 5 million people in the United States live with heart failure, a condition in which the heart is unable to pump blood around the body effectively. The causes and types of heart failure vary greatly, and treatment must be tailored to each patient. In some cases, doctors will prescribe a class of diuretic drugs called aldosterone antagonists.

20 Sep 2011

Powerful new antibiotic treatment for MRSA and C. difficile bugs

MGB Biopharma, a biopharmaceutical company which has licensed technology from the University of Strathclyde in Glasgow, Scotland, is developing a powerful new antibiotic treatment for resistant infections including the deadly MRSA and Clostridium difficile (C. diff.) bugs.

20 Sep 2011

ADHD symptoms might affect adaptive abilities, quality of life for children with ASD

Research supported by the Autism Speaks Autism Treatment Network (ATN), demonstrating that symptoms of attention deficit and hyperactivity worsen quality of life for individuals with autism spectrum disorders (ASD), was presented today at the Society for Developmental & Behavioral Pediatrics Annual Meeting in San Antonio, Texas.

20 Sep 2011

Mayo Clinic, SK biopharmaceuticals collaborate to discover new ALS drugs

South Korean biotech SK biopharmaceuticals announced yesterday that they signed an agreement to collaborate with the Mayo Clinic for the discovery of new drugs targeting Amyotrophic Lateral Sclerosis.

20 Sep 2011

Preclinical studies shows EmPAC more effective than Taxol

Cornerstone Pharmaceuticals, Inc. has announced the publication of data from preclinical studies on EmPAC™, its nanoparticle reformulation of paclitaxel, in the August issue of the Journal of Nanoscience and Nanotechnology. The publication highlights data demonstrating improved safety and efficacy of EmPAC™ versus Taxol®, the generic formulation of paclitaxel and one of the most widely prescribed chemotherapies. EmPAC™ is a nanoemulsion formulation of Paclitaxel and is the lead product candidate of Cornerstone’s proprietary Emulsiphan™ cancer selective delivery nanotechnology platform. Taxol®, an injectable formulation of Paclitaxel, is currently used to treat a variety of cancers, including ovarian carcinomas, breast cancer, non-small cell lung cancer, and AIDS-related Kaposi’s sarcoma.

19 Sep 2011

NovaSterilis awarded patent for novel preparation and sterilization of ‘Green State’ devices

NovaSterilis Inc. has been granted US Patent No 7,988,892. The patent, dated August 2, 2011 is entitled “Preparation and Sterilization of Green State Devices Using a Supercritical Fluid Sterilant.”

19 Sep 2011

Aestus to develop ATx09-002 for treatment of neuropathic pain

Aestus Therapeutics, Inc. and Prosidion Ltd., a wholly owned subsidiary of Astellas Pharma Inc., announced today a license agreement providing Aestus with exclusive, world-wide rights to the Prosidion investigational product PSN-357.

19 Sep 2011

Additional data on safety, tolerability of Cempra's solithromycin to be presented at 51st ICAAC

Cempra Pharmaceuticals today announced abstracts to be presented on its fourth generation macrolide and novel fluoroketolide antibiotic, solithromycin (CEM-101), at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), September 17 to 20, 2011, in Chicago. The abstracts provide additional data that demonstrate the safety and routes of administration of CEM-101, a new generation macrolide.

17 Sep 2011

Researchers show how protein fortilin promotes growth of cancer cells

Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of Texas Medical Branch may lead to treatments for a range of cancers and atherosclerosis, which p53 also helps prevent, and appears in the current print issue of the Journal of Biological Chemistry.

17 Sep 2011

Nanion’s automated patch clamp platforms show unparalleled results using stem cell derived cardiomyocytes

The Patchliner and the SyncroPatch 96 have successfully been used for compound analysis under current- and voltage clamp recording conditions using different stem cell-derived cardiomyocytes. The exceptional cell-platform-compatibility and the unique experimental possibilities offered by Nanion’s platforms open up whole new avenues for compound safety testing.

16 Sep 2011

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from an investigational Phase 3b clinical study in which the addition of ONGLYZA (saxagliptin) 5 mg to ongoing insulin therapy (with or without metformin) maintained reductions of blood sugar levels (glycosylated hemoglobin levels, or HbA1c) in adult patients with type 2 diabetes compared to the addition of placebo (with or without metformin) from 24 to 52 weeks.

16 Sep 2011

Silence receives U.S. patent entitled, 'Use of Protein Kinase N beta'

Silence Therapeutics plc, a leading RNA interference (RNAi) therapeutics company, announces the issuance of patent 4810095 entitled "Use of Protein Kinase N beta" by the Japanese Patent Office.

16 Sep 2011

Anavex Life Sciences to present data on lead compound for Alzheimer’s at Japan Neuroscience Society

Anavex Life Sciences Corp. will present the most recent data showing the therapeutic potential of ANAVEX compounds in animal models of Alzheimer’s disease at a special symposium of the 34th annual meeting of the Japan Neuroscience Society. The symposium is being held in Yokohama, Japan from September 15-17, 2011.

15 Sep 2011

China Botanic third-quarter net sales increase 33.6% to $12.4 million

China Botanic Pharmaceutical Inc., a developer, manufacturer and distributor of botanical products, bio-pharmaceuticals and traditional Chinese medicines in China, today announced financial results for the three months ended July 31, 2011.

15 Sep 2011

Gender disparities in developing countries relatively small at birth but grow in adolescence, UNICEF report says

A UNICEF report released on Tuesday suggests that gender disparities between boys and girls in developing countries are relatively small in children's early years, but as children approach adolescence, gaps widen in areas such as education, health, nutrition and protection, Xinhua reports.

15 Sep 2011

First effective blood-stage vaccine against malaria

Scientists have identified the first effective blood-stage malaria vaccine, according to a New England Journal of Medicine study from University of Maryland School of Medicine researchers, in collaboration with the University of Bamako in Mali, West Africa, and other partners.

15 Sep 2011

Enrollment commences in ConjuChem's CJC-1134-PC Phase 2 trial for Type 2 diabetes

ConjuChem, LLC, a biotechnology company dedicated to the discovery of novel therapeutics, today announced it has initiated patient enrollment for its Phase 2 clinical trial of its proprietary GLP-1 receptor agonist drug, CJC-1134-PC, in patients with Type 2 diabetes mellitus who are receiving metformin monotherapy.

15 Sep 2011

Compound News and Research

Survey confirms low BPA exposure levels in food packaging

Maternal exposures to BPA are not transmitted to fetus: FDA study

Niiki Pharma announces positive data from ongoing trial of novel anti-cancer agent NKP-1339

U-M Professor to review data from three prominent studies on heart failure

Powerful new antibiotic treatment for MRSA and C. difficile bugs

ADHD symptoms might affect adaptive abilities, quality of life for children with ASD

Mayo Clinic, SK biopharmaceuticals collaborate to discover new ALS drugs

Preclinical studies shows EmPAC more effective than Taxol

NovaSterilis awarded patent for novel preparation and sterilization of ‘Green State’ devices

Aestus to develop ATx09-002 for treatment of neuropathic pain

Additional data on safety, tolerability of Cempra's solithromycin to be presented at 51st ICAAC

Researchers show how protein fortilin promotes growth of cancer cells

Nanion’s automated patch clamp platforms show unparalleled results using stem cell derived cardiomyocytes

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Silence receives U.S. patent entitled, 'Use of Protein Kinase N beta'

Anavex Life Sciences to present data on lead compound for Alzheimer’s at Japan Neuroscience Society

China Botanic third-quarter net sales increase 33.6% to $12.4 million

Gender disparities in developing countries relatively small at birth but grow in adolescence, UNICEF report says

First effective blood-stage vaccine against malaria

Enrollment commences in ConjuChem's CJC-1134-PC Phase 2 trial for Type 2 diabetes

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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