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New melanoma drug in the pipeline from Plexxikon and Roche

Researchers from biotech company Plexxikon have found that their candidate drug for skin cancer melanomas can be administered more effectively in early stages of the disease.

9 Sep 2010

NovaSterilis issued US patent

NovaSterilis Inc. has been issued US Patent # 7,771,652 B2 for “Combined Use of an Alkaline Earth Metal Compound and a Sterilizing Agent to Maintain Osteoinduction Properties of a Demineralized Bone Matrix”

9 Sep 2010

Caliper launches toolkit for direct co-registration of images from multiple preclinical imaging modalities

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery, life sciences research and molecular diagnostics, today introduced software and accessory items to enable the direct co-registration of images from multiple preclinical imaging modalities.

9 Sep 2010

Researchers discover first compound to activate enzyme telomerase in human body

Sierra Sciences, in collaboration with TA Sciences, Geron Corporation, PhysioAge, and the Spanish National Cancer Research Center (CNIO), has announced the first compound ever discovered that activates the enzyme telomerase in the human body - a critical prerequisite for technology that could arrest or reverse the aging process in humans.

9 Sep 2010

Lactic acid fermentation reduces acrylamide formation during production of potatoes and coffee

A small research-based Norwegian company has developed a method to reduce the formation of the carcinogenic compound acrylamide during industrial production of potatoes and coffee. International food giants are paying attention.

9 Sep 2010

Researchers synthesize new compounds to reduce A-beta 42 peptide in Alzheimer's disease

A team of scientists, led by University of California, San Diego School of Medicine researchers, has synthesized hundreds of new compounds with the potential of reducing the production of the A-beta 42 peptide, a primary component of Alzheimer's disease (AD).

9 Sep 2010

GE Healthcare's flutemetamol phase 2 study results published in 'Annals of Neurology'

GE Healthcare announced today that results from its multicenter phase 2 study of flutemetamol were published in the September issue of Annals of Neurology. Flutemetamol is an investigational positron emission tomography (PET) imaging agent being developed by GE Healthcare, in the field of brain imaging.

9 Sep 2010

Champions Biotechnology signs agreement to test Cephalon's CEP-32496 in Biomerk Tumorgraft platform

Champions Biotechnology, Inc., an oncology drug development company with a predictive preclinical platform aimed at accelerating the development and enhancing the value of oncology drugs, announced the establishment of an agreement with Cephalon, Inc., a global biopharmaceutical company, for the testing of the Cephalon novel B-Raf inhibitor CEP-32496 in Champions' Biomerk Tumorgraft™ platform.

8 Sep 2010

ImmuneRegen's Homspera with Scancell's ImmunoBody technology improves immune response for cancer

ImmuneRegen BioSciences, Inc., a wholly owned subsidiary of IR BioSciences Holdings, Inc. today announced that treatment with its lead compound, Homspera, in combination with a DNA vaccine utilizing Scancell's ImmunoBody technology significantly improved the immune response of the vaccine in an animal model.

8 Sep 2010

Levi Strauss, Hennes & Mauritz implement global ban on sandblasting

As a commitment to the health and safety of workers across the apparel industry, Levi Strauss & Co. and Hennes & Mauritz AB (H&M) today announced plans to implement a global ban on sandblasting in all of their future product lines.

8 Sep 2010

Researchers find blebbistatin chemically inhibits NMII, enhances survival of stem cells

Human pluripotent stem (hPS) cells can generate any given cell type in the adult human body, which is why they are of interest to stem cell scientists working on finding therapies for spinal cord injuries, Parkinson's disease, burns, heart disease, diabetes, arthritis, and other ailments.

8 Sep 2010

NGP 555 compound effective in preventing amyloid pathology of Alzheimer's disease

In the Sept. 9, 2010 issue of Neuron, Neurogenetic Pharmaceuticals, Inc. (NGP) reports proof of concept studies that show its proprietary compound, NGP 555, is effective in preventing the amyloid pathology of Alzheimer's disease (AD) in a transgenic mouse model.

8 Sep 2010

Biomoda joins Saccomanno Research Institute to advance CyPath technology for cancer detection

Cancer diagnostics company Biomoda, Inc. is working with the Saccomanno Research Institute to advance Biomoda's patented system for measuring the photon emission rate of CyPath-stained cells to detect early-stage lung cancer.

8 Sep 2010

Positive immune responses elicited from Scancell's DNA vaccine in combination with ImmuneRegen's Homspera

Scancell Holdings Plc, the developer of therapeutic cancer vaccines, announces that a treatment utilising a DNA vaccine based on its ImmunoBody® technology, in combination with ImmuneRegen BioSciences, Inc.®'s lead compound, Homspera®, has significantly improved the immune response of the vaccine in an animal model. Follow-up studies are currently being performed to optimize the effects of Homspera in enhancing the next generation of Scancell's cancer vaccines.

7 Sep 2010

Bend Research expands hot-melt extrusion pharmaceutical manufacturing capabilities

Bend Research Inc., a leading independent drug-formulation development and manufacturing company, announced today that it is expanding its pharmaceutical manufacturing capabilities for hot-melt extrusion.

7 Sep 2010

TenX Biopharma recommences enrollment in suspended Phase III trial for cutaneous T-cell lymphoma

TenX Biopharma, Inc. announced today that it has re-initiated enrollment in the pivotal Phase III clinical trial assessing zanolimumab treatment for cutaneous T-cell lymphoma (CTCL) patients (ClinicalTrials.gov identifier: NCT00127881). The trial enrollment was suspended in October 2008 while Genmab was seeking a out-license agreement to further develop the compound. TenX Biopharma acquired global rights to zanolimumab in February, 2010 from Genmab.

7 Sep 2010

DSM, PolyTherics enter agreement for HiPEG IFN alpha-2a product development

DSM BioSolutions, DSM's microbial fermentation CMO business unit and PolyTherics Limited an innovator in precision engineering of proteins, today announced that they have entered into an agreement for the process development and manufacture of PolyTherics' lead biobetter product, HiPEG IFN alpha-2a.

7 Sep 2010

Chemicals in non-stick cookware elevates cholesterol level among children: Report

Children and teens with higher blood levels of chemicals used in the production of non-stick cookware and waterproof fabrics appear more likely to have elevated total and LDL cholesterol levels, according to a report in the September issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

7 Sep 2010

Single-dose of experimental malaria drug clears parasites in mice, represents potential new class of drugs to treat malaria in humans

An experimental malaria drug was shown to effectively treat the disease in mice with only a single dose, according to a study published Thursday in the journal Science, Reuters reports (Kelland, 9/2). The new drug, known as NITD609, "represents an entirely new class of medicines to treat malaria ... Human trials, backed by Swiss pharmaceutical giant Novartis AG, could begin later this year," the Wall Street Journal writes (Naik, 9/3).

4 Sep 2010

MIT develops safer, simpler way to attach phosphorus to organic compounds

Phosphorus, a mineral element found in rocks and bone, is a critical ingredient in fertilizers, pesticides, detergents and other industrial and household chemicals. Once phosphorus is mined from rocks, getting it into these products is hazardous and expensive, and chemists have been trying to streamline the process for decades.

4 Sep 2010

Compound News and Research

New melanoma drug in the pipeline from Plexxikon and Roche

NovaSterilis issued US patent

Caliper launches toolkit for direct co-registration of images from multiple preclinical imaging modalities

Researchers discover first compound to activate enzyme telomerase in human body

Lactic acid fermentation reduces acrylamide formation during production of potatoes and coffee

Researchers synthesize new compounds to reduce A-beta 42 peptide in Alzheimer's disease

GE Healthcare's flutemetamol phase 2 study results published in 'Annals of Neurology'

Champions Biotechnology signs agreement to test Cephalon's CEP-32496 in Biomerk Tumorgraft platform

ImmuneRegen's Homspera with Scancell's ImmunoBody technology improves immune response for cancer

Levi Strauss, Hennes & Mauritz implement global ban on sandblasting

Researchers find blebbistatin chemically inhibits NMII, enhances survival of stem cells

NGP 555 compound effective in preventing amyloid pathology of Alzheimer's disease

Biomoda joins Saccomanno Research Institute to advance CyPath technology for cancer detection

Positive immune responses elicited from Scancell's DNA vaccine in combination with ImmuneRegen's Homspera

Bend Research expands hot-melt extrusion pharmaceutical manufacturing capabilities

TenX Biopharma recommences enrollment in suspended Phase III trial for cutaneous T-cell lymphoma

DSM, PolyTherics enter agreement for HiPEG IFN alpha-2a product development

Chemicals in non-stick cookware elevates cholesterol level among children: Report

Single-dose of experimental malaria drug clears parasites in mice, represents potential new class of drugs to treat malaria in humans

MIT develops safer, simpler way to attach phosphorus to organic compounds

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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