Genes News and Research

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What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

Researchers compared clinical outcomes of COVID-19 cases due to SARS-CoV-2 Omicron BA.2 and Omicron BA.4/BA.5 variants based on the Kaiser Permanente Southern California (KPSC) health records between April 29 and July 2, 2022.

4 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

New easy-to-use test could rapidly diagnose heart attacks and cancers

Imperial researchers have built a new easy-to-use test that could diagnose non-infectious diseases like heart attacks and cancers more quickly.

4 Aug 2022

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

We are increasingly being exposed to endocrine-disrupting chemicals (EDCs) that interfere with the normal functioning of our hormones. Bisphenol A (BPA) and phthalates, which are widely used in consumer products including plastics, aluminum cans, pharmaceuticals, and cosmetics, are well-known EDCs.

4 Aug 2022

Children's noses better at inhibiting SARS-CoV-2 infections than adults

University of Queensland-led research has found the lining of children's noses is better at inhibiting SARS-CoV-2 infections than adult noses.

3 Aug 2022

Study: Genes involved in coronary heart disease may be nearly the same for everyone

The genes involved in coronary heart disease, the most common form of heart disease, appear to be nearly the same for everyone, according to a VA study.

3 Aug 2022

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

3 Aug 2022

UVA researchers receive $15 million from LeDucq Foundation to advance understanding of atherosclerosis

The Boston-based LeDucq Foundation has awarded $15 million to researchers at UVA Health and their collaborators to advance our understanding of atherosclerosis, or hardening of the arteries, and find better ways to treat it.

3 Aug 2022

What is the prevalence of carbapenem-resistant Enterobacterales among individuals with and without health risk factors?

Researchers assessed carbapenem-resistant Enterobacterales (CRE) epidemiology across eight US metropolitan areas between 1 January 2012 and 31 December 2015.

3 Aug 2022

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

3 Aug 2022

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

In a new study, researchers assessed the genetic variation among targets of Alzheimer's disease risk and anti-diabetic drugs.

3 Aug 2022

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Timothy Huang, Ph.D., has been awarded $2.8 million by the National Institute on Aging (NIA) to continue his work on Alzheimer's disease.

2 Aug 2022

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/Medical University of Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder.

2 Aug 2022

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring cells.

2 Aug 2022

Hormonal treatment provides long-term benefit for premenopausal women with breast cancer

To investigate the long-term benefit of hormone-lowering treatment, researchers at Karolinska Institutet in Sweden have done a 20-year follow-up of premenopausal women with breast cancer.

2 Aug 2022

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Disease of the microscopic blood vessels that feed the white matter of our brain is associated with worse cognitive function and memory deficits in individuals with Alzheimer's, scientists report.

2 Aug 2022

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

A new study shows how mutation of the ADAR1 gene sets off biochemical pathways that produce an autoimmune response that harms the developing brain and other areas of the body.

2 Aug 2022

Shear-thinning biomaterial-based minimally invasive strategy for delivery of targeted immunotherapy

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed and optimized a minimally invasive method for more targeted, efficient, and sustained delivery of immunotherapeutic treatments for cancer.

2 Aug 2022

Researchers characterize a novel gene likely to cause neurological disorders in humans

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/MedUni Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder. Using data from two young patients with neurological symptoms, the researchers from both groups found evidence of a novel function for the FIBCD1 gene in the brain, and a potentially pivotal role in diseases such as autism, ADHD, schizophrenia, and neurodegenerative disorders including Alzheimer's. The study makes an important contribution to the understanding of the extracellular matrix in the brain and its associated neurological diseases.

2 Aug 2022

Genes News and Research

What is the severity of SARS-CoV-2 Omicron BA.4 and BA.5 variant infections in relation to BA.2 infections?

CHOP helps launch new computational platform to harmonize pediatric cancer data

New easy-to-use test could rapidly diagnose heart attacks and cancers

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

Children's noses better at inhibiting SARS-CoV-2 infections than adults

Study: Genes involved in coronary heart disease may be nearly the same for everyone

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

UVA researchers receive $15 million from LeDucq Foundation to advance understanding of atherosclerosis

What is the prevalence of carbapenem-resistant Enterobacterales among individuals with and without health risk factors?

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Hormonal treatment provides long-term benefit for premenopausal women with breast cancer

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

Shear-thinning biomaterial-based minimally invasive strategy for delivery of targeted immunotherapy

Researchers characterize a novel gene likely to cause neurological disorders in humans

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