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Scientists identify potential biomarkers associated with positive immunotherapy response

Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy treatment.

26 Jun 2023

New hope for cystic fibrosis patients as groundbreaking treatment enters clinical trial

Clinical testing is underway for a potentially groundbreaking new treatment for cystic fibrosis. Pioneered by scientists at Carle Illinois College of Medicine at the University of Illinois Urbana-Champaign and the Carver College of Medicine at the University of Iowa in partnership with the spin-out biotechnology company, cystetic Medicines, this promising inhalable molecular prosthetic is intended to improve lung function in people with CF who cannot benefit from current therapies.

26 Jun 2023

Unveiling the truth: tropical hunter-gatherers' diets contradict Paleo diet assumptions

Researchers assessed the dietary variations of tropical hunters and gatherers.

26 Jun 2023

Research sheds light on how steroids affect cancer Immunotherapy

Immunotherapy is among the newest and most potent weapons against cancer. It prompts the immune system to recognize tumors as intruders in the body and attack. But not all patients respond well to immunotherapy. Why? Scientists aren't always sure.

23 Jun 2023

Beware the chair: sedentary habits harm bones, contribute to higher body fat, study reveals

Researchers compared the associations of sedentary and physical activities with factors such as body fat.

23 Jun 2023

The use of bacterial colonists as therapy carriers is gaining interest for treating cancer

Study describes the use of engineered commensal bacteria to increase antitumor immunity.

23 Jun 2023

Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients

Researchers investigated whether black carbon particles in the blood increased COVID-19 severity.

23 Jun 2023

Key viral protein produced by influenza A can shred a host cell's genetic materials, finds study

Influenza A is one of two influenza viruses that fuel costly annual flu seasons and is a near constant threat to humans and many other animals. It's also responsible for occasional pandemics that, like the one in 1918, leave millions dead and wreak havoc on health systems and wider society.

23 Jun 2023

Women with higher maternal BMI have shorter breastfeeding duration, finds study

Breastfeeding has significant benefits for both maternal and child health. Research has indicated that women with higher body mass index (BMI) have shorter durations of breastfeeding, but few underlying mechanisms have been identified.

23 Jun 2023

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn.

23 Jun 2023

Mapping the by-products of bacteria processing amino acids associated with cardiovascular disease

A Cleveland Clinic research team recently published an "atlas" of metabolites associated with cardiovascular disease in the European Heart Journal. The novel findings provide key details about the routes and potential branching paths taken by bacteria and metabolic by-products, metabolites.

23 Jun 2023

Deciphering a biochemical mechanism explains the center of protein factories

Based on genetic blueprints, individual amino acids are assembled into long amino acid chains, the proteins, in the protein factories of our cells, the ribosomes. Each newly formed protein starts with the amino acid methionine.

23 Jun 2023

Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Dr. Niklas Klümper, resident at the Department of Urology and Pediatric Urology of the University Hospital Bonn (UKB) and working group leader at the Institute for Experimental Oncology (IEO), and Dr. Jonas Saal, resident at the Medical Clinic III for Oncology, Hematology, Immune-Oncology and Rheumatology of the UKB, demonstrated a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.

22 Jun 2023

Protein C News and Research

Scientists identify potential biomarkers associated with positive immunotherapy response

New hope for cystic fibrosis patients as groundbreaking treatment enters clinical trial

Unveiling the truth: tropical hunter-gatherers' diets contradict Paleo diet assumptions

Research sheds light on how steroids affect cancer Immunotherapy

Beware the chair: sedentary habits harm bones, contribute to higher body fat, study reveals

The use of bacterial colonists as therapy carriers is gaining interest for treating cancer

Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients

Key viral protein produced by influenza A can shred a host cell's genetic materials, finds study

Women with higher maternal BMI have shorter breastfeeding duration, finds study

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Mapping the by-products of bacteria processing amino acids associated with cardiovascular disease

Deciphering a biochemical mechanism explains the center of protein factories

Study reveals contrasting effects of sucralose on insulin and glucose control

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

UQ researchers uncover the structure of Langya virus' fusion protein

A lower dietary carbohydrate/fat ratio may be effective in improving cognitive performance

Uncovering Hidden Diversity in Human Gut Anatomy

Parental loss at a young age affects a person’s immune system later in life

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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