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Novel miRNA-based therapy shows promise for treatment of drug-resistant biliary tract cancer

Biliary tract cancers (BTCs) including cholangiocarcinoma (CCA) and gallbladder cancer (GBC) are becoming more prevalent globally.

30 Nov 2023

Study sheds new light on the profound influence of music on our moral compass

A new study, published in PLOS ONE, has uncovered a remarkable connection between individuals' musical preferences and their moral values, shedding new light on the profound influence that music can have on our moral compass.

29 Nov 2023

Novel TMS protocol shows promise for treating hard-to-treat depression

By making slight modifications to an already approved brain stimulation technique called transcranial magnetic stimulation (TMS), researchers have reported profound improvement in patients with hard-to-treat depression.

29 Nov 2023

Macrocyclic compounds: A promising class of drugs for cancer treatment

This review was designed by Professor Xiaoling Song and Professor Biao Jiang and written by Pr. Xiaoling Song and a Ph.D. student, Yifan Wu (Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University) to summarize the application of macrocyclic molecules in cancer treatment.

29 Nov 2023

C-Path's TRxA and Celdara Medical announce MOU to identify and advance promising new therapeutics

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) and Celdara Medical today announced the signing of a Memorandum of Understanding (MOU) aimed at identifying and advancing promising new therapeutics in areas of high unmet medical need.

29 Nov 2023

Mechanically reprogrammed connective tissue cells can promote wound healing

Researchers at PSI and ETH Zurich have taken connective tissue cells that have been mechanically reprogrammed to resemble stem cells and transplanted them into damaged skin.

29 Nov 2023

Imaging approach provides objective evidence for the involvement of neck muscles in primary headaches

Researchers have identified objective evidence of how the neck muscles are involved in primary headaches, according to a study being presented today at the annual meeting of the Radiological Society of North America.

29 Nov 2023

OCD therapy reshapes brain connectivity for better cognitive control

A first-line therapy for obsessive-compulsive disorder (OCD) reshapes connectivity of the brain, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier.

29 Nov 2023

Accelerating antibody therapy with INTEGRA pipettes

INTEGRA Biosciences has awarded 50 EVOLVE manual pipettes, GRIPTIPS® pipette tips worth US $1000 and various lab accessories to UK-based start-up Creasallis, helping to accelerate its pioneering research into improving the penetration of therapeutic antibodies into tumors.

From INTEGRA Biosciences 29 Nov 2023

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Researchers demonstrated clustered regularly interspersed short palindromic repeats (CRISPR)-mediated elimination of glioblastoma (GBM) cells.

29 Nov 2023

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Psoriasis etiopathogenesis and treatment.

29 Nov 2023

Exploring associations between BMI, cardiometabolic diseases, and cancer risk

Researchers evaluate the associations of body mass index, type 2 diabetes, and cardiovascular disease with cancer risk.

29 Nov 2023

Study finds promising new approach to treating locally advanced pancreatic cancer

A new Phase Ib/II study from researchers at The University of Texas MD Anderson Cancer Center and Moffitt Cancer Center found that combining sensitizing drugs with a specific form of radiation therapy may be more effective in patients with locally advanced pancreatic cancer, yielding a higher progression-free survival (PFS) and overall response rate (ORR).

28 Nov 2023

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins.

28 Nov 2023

Social support needed to reduce the barriers in accessing cardiac rehabilitation

Noted experts in cardiovascular rehabilitation attending the Third Jim Pattison-Mazankowski Alberta Heart Institute Cardiac Rehabilitation Symposium (Banff, April 21-23, 2023) observed that although cardiac rehabilitation benefits diverse groups of patients and affords the most cost-effective prevention for recurrent events, it is grossly underutilized globally.

28 Nov 2023

New heart organoid model could revolutionize drug development and toxicology studies

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists – so far.

28 Nov 2023

Ohio State Wexner Medical Center wins $14 million award for aspirin dose study

A research team at The Ohio State University Wexner Medical Center and College of Medicine has been approved for a $14 million award from the Patient-Centered Outcomes Research Institute (PCORI) to study whether a higher daily dose of aspirin is more effective in decreasing the risk of dangerous blood pressure complications among some pregnant people.

28 Nov 2023

Radiation therapy could improve cardiac function in heart failure

Cardiologists and radiation oncologists at Washington University School of Medicine in St. Louis pioneered the use of radiation therapy - a strategy typically used against cancer - to treat patients with a life-threatening abnormal heart rhythm called ventricular tachycardia.

28 Nov 2023

All-cause thyrotoxicosis associated with increased risk of cognitive disorders

Thyrotoxicosis - excess thyroid hormone levels in the body - has been linked to an increased risk of cognitive disorders among older adults, according to a new study from Johns Hopkins Medicine.

28 Nov 2023

FDA awards grant for phase 1 clinical trial of experimental AML/MDS treatment

Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) - two related blood diseases that disproportionally strike older adults - are notoriously difficult to treat and associated with high relapse rates.

28 Nov 2023

Therapy News and Research

Novel miRNA-based therapy shows promise for treatment of drug-resistant biliary tract cancer

Study sheds new light on the profound influence of music on our moral compass

Novel TMS protocol shows promise for treating hard-to-treat depression

Macrocyclic compounds: A promising class of drugs for cancer treatment

C-Path's TRxA and Celdara Medical announce MOU to identify and advance promising new therapeutics

Mechanically reprogrammed connective tissue cells can promote wound healing

Imaging approach provides objective evidence for the involvement of neck muscles in primary headaches

OCD therapy reshapes brain connectivity for better cognitive control

Accelerating antibody therapy with INTEGRA pipettes

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Exploring associations between BMI, cardiometabolic diseases, and cancer risk

Study finds promising new approach to treating locally advanced pancreatic cancer

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Social support needed to reduce the barriers in accessing cardiac rehabilitation

New heart organoid model could revolutionize drug development and toxicology studies

Ohio State Wexner Medical Center wins $14 million award for aspirin dose study

Radiation therapy could improve cardiac function in heart failure

All-cause thyrotoxicosis associated with increased risk of cognitive disorders

FDA awards grant for phase 1 clinical trial of experimental AML/MDS treatment

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