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Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs).

6 Oct 2023

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alzheimer's disease.

5 Oct 2023

Researchers identify new potential treatments for children with rare genetic conditions of blood vessels

A research team at the Francis Crick Institute and Great Ormond Street Hospital (GOSH)/UCL Great Ormond Street Institute of Child Health have identified new potential treatments for children with rare genetic conditions of blood vessels, which cause severe, lifelong, and disabling symptoms like seizures and impaired development.

5 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Genetics linked to placental growth and risk of preeclampsia

New research has shed light on how genetics influences the growth of the placenta, revealing a link to risk of disease in the mother.

5 Oct 2023

Organoid medicine reveals promising covid-19 treatment target

When the new SARS-CoV-2 virus began killing thousands of people every week, physicians and scientists around the globe raced to learn why the new pathogen was so deadly.

5 Oct 2023

CRISPR gene editing study provides insights into how autism gene affects brain development

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

5 Oct 2023

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Challenges associated with the development and design of neoantigen cancer vaccines.

5 Oct 2023

Optimized protocol to prevent disease transmission through maternal mitochondrial DNA carryover

Researchers discuss a novel technique to minimize the risk of mtDNA carryover, thereby preventing genetic risk and clinical mitochondrial disease.

5 Oct 2023

Disinfectants used in food production may exacerbate antibiotic resistance

Yes, say researchers - who suspect that disinfectants used in food production may in fact be exacerbating a global public health problem.

5 Oct 2023

Progress and challenges in completing the human gene catalogue

A group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding RNAs, and advocated for a universal annotation standard for clinical use.

5 Oct 2023

Cancer tumors hijack genetic program of developing nerves, study shows

Cancer tumors "hijack" the genetic program used by developing nerves. This is shown in a study by researchers at Umeå University, Sweden.

4 Oct 2023

USC receives $2 million grant to advance cell and gene therapy research

The Keck School of Medicine of USC has received $2 million from the California Institute of Regenerative Medicine (CIRM) to further augment its newly launched cGMP Laboratory, a state-of-the-art facility designed to advance early-stage research into clinically viable cell and gene therapies.

4 Oct 2023

Study finds cluster of common conditions may signal early onset of type 2 diabetes

New research presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Hamburg (2-6 Oct), reveals a marked increase in several common conditions in the years leading up to, and immediately prior to, type 2 diabetes diagnosis, suggesting considerably earlier diagnosis might be possible in some patients.

4 Oct 2023

How vitamin D and genetics shape early brain development

The study examined how vitamin D levels and vitamin D binding protein genotypes in both pregnant mothers and their children aged 3-5, impact early childhood neurodevelopment. Findings suggest that higher vitamin D concentrations in children were associated with better neurodevelopmental scores, with additional influences from sociodemographic factors and certain genetic variations.

4 Oct 2023

Study identifies potential new way to protect premature babies from deadly infection

Premature babies in neonatal care units are extremely vulnerable, and susceptible to life-threatening infections.

4 Oct 2023

Genetics may influence a person’s ability to adhere to a vegetarian diet

From Impossible Burger to "Meatless Mondays," going meat-free is certainly in vogue. But a person's genetic makeup plays a role in determining whether they can stick to a strict vegetarian diet, a new Northwestern Medicine study has found.

4 Oct 2023

Wood cookstove use linked to gastric cancer risk

Researchers conducted a population-based study with a case–control design in rural areas of Honduras in Central America to examine whether wood cookstove use by indigenous populations was associated with increased risk of stomach cancers, including gastric adenocarcinoma.

4 Oct 2023

New study reveals inequalities in the provision of heart valve replacement surgery

There are striking inequalities in the provision of major (aortic) heart valve replacement surgery across England, with women, Black and Asian people, and those living in areas of deprivation much less likely to receive the life-saving procedure, suggests a large data analysis, published in the open access journal Open Heart.

4 Oct 2023

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

The connection between the CHD gene and autism-related gastrointestinal (GI) manifestations.

4 Oct 2023

Genetic News and Research

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

Researchers identify new potential treatments for children with rare genetic conditions of blood vessels

Researchers spearhead a new method to hone in on new cancer drug targets

Genetics linked to placental growth and risk of preeclampsia

Organoid medicine reveals promising covid-19 treatment target

CRISPR gene editing study provides insights into how autism gene affects brain development

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Optimized protocol to prevent disease transmission through maternal mitochondrial DNA carryover

Disinfectants used in food production may exacerbate antibiotic resistance

Progress and challenges in completing the human gene catalogue

Cancer tumors hijack genetic program of developing nerves, study shows

USC receives $2 million grant to advance cell and gene therapy research

Study finds cluster of common conditions may signal early onset of type 2 diabetes

How vitamin D and genetics shape early brain development

Study identifies potential new way to protect premature babies from deadly infection

Genetics may influence a person’s ability to adhere to a vegetarian diet

Wood cookstove use linked to gastric cancer risk

New study reveals inequalities in the provision of heart valve replacement surgery

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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