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Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor functions, which eventually leads to death within 5 years of its onset.

1 Feb 2024

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment resistance in chronic lymphocytic leukemia (CLL) and related blood cancers.

1 Feb 2024

Specific epigenetic pathway found to be involved in the development of melanoma drug resistance

One of the major challenges in cancer research and clinical care is understanding the molecular basis for therapeutic resistance as a major cause of long term treatment failures.

1 Feb 2024

New approach offers hope for regaining lost memories in Alzheimer's

While newly approved drugs for Alzheimer's show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory.

1 Feb 2024

Study: Most stroke survivors can safely take two types of common antidepressants

Most stroke survivors were able to safely take two types of common antidepressants, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

Nerve stimulation plus physical rehabilitation may boost recovery of arm and hand function

Combining brain stimulation with intense physical rehabilitation helped stroke survivors recover movement in their arms and hands and maintain these improvements for one year, according to a study to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

New sequencing tool speeds up SARS-CoV-2 outbreak response and informs treatment

Announcing a new article publication for Zoonoses journal. In the context of two Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreaks involving local transmission and an international flight, the authors of this article used meta-transcriptome and multi-amplicon sequencing to successfully acquire the complete viral genome sequences from clinical samples with varying viral loads.

1 Feb 2024

CT scans may be better first step for evaluating chest pain

Previous studies have found less than 40% of patients with stable chest pain undergoing invasive coronary angiography are found to have obstructive coronary artery disease.

1 Feb 2024

Virtual relaxation therapy reduces distress in end-of-life care

A new study published in Frontiers in Virtual Reality explored the effectiveness of a psychological strategy called Flourishing-Life-Of-Wish Virtual Reality Therapy (FLOW-VRT)® in helping people cope with their symptoms and achieve relaxation at the end of life.

1 Feb 2024

CRISPR revolutionized: New method edits genes directly in the body

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.

1 Feb 2024

Early whole blood transfusion boosts survival in trauma patients

Significant bleeding due to traumatic injury is the number one cause of preventable deaths in the U.S., with the majority of deaths occurring within six hours.

31 Jan 2024

Study paves the way for improving personalized treatment of patients with glioblastoma

A study led by the ITACA Institute of the Universitat Politècnica de València, with the participation of the Institut Català d'Oncologia (ICO), the Institut Investigació Germans Trias I Pujol (IGTP) and the Hospital Clinic de Barcelona, opens up a novel approach for improving personalized treatments for patients with glioblastoma, one of the most aggressive types of cancer in existence today.

31 Jan 2024

Pioneering repository aims to raise visibility and awareness about people with mental illnesses

Metaphors are not just literary devices for writers to embellish their texts. They are linguistic tools used in everyday life, in most cases with the aim of better understanding and conveying the reality of the world around us.

31 Jan 2024

Scientists coax a deadly bacterium to destroy itself from the inside out

Northwestern University researchers have successfully coaxed a deadly pathogen to destroy itself from the inside out.

31 Jan 2024

Scientists uncover a way to "hack" neurons' internal clocks to speed up brain cell development

The neurons that make up our brains and nervous systems mature slowly over many months.

31 Jan 2024

Immunocompromised patients show prolonged SARS-CoV-2 infection and unique mutations

study identifies risk factors for prolonged SARS-CoV-2 infection in immunocompromised patients, revealing that B-cell dysfunction, solid organ transplantation, and AIDS lead to longer infections and unique spike mutations.

31 Jan 2024

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

A recent study co-authored by Dr. Matthew Segar, a third-year cardiovascular disease fellow at The Texas Heart Institute and led by his research and residency mentor, University of Texas Southwestern Medical Center's Dr. Ambarish Pandey, utilized a machine learning-based approach to identify, understand, and predict diuretic responsiveness in patients with acute decompensated heart failure (ADHF).

31 Jan 2024

AI-based applications for personalized cancer medicine and related regulatory challenges: An overview

Personalized therapies could improve the treatment of many diseases in the future. Cancer medicine in particular has made significant progress in recent years.

31 Jan 2024

Ketamine therapy for mental health a ‘wild West’ for doctors and patients

In late 2022, Sarah Gutilla's treatment-resistant depression had grown so severe, she was actively contemplating suicide.

31 Jan 2024

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

30 Jan 2024

Therapy News and Research

Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

Specific epigenetic pathway found to be involved in the development of melanoma drug resistance

New approach offers hope for regaining lost memories in Alzheimer's

Study: Most stroke survivors can safely take two types of common antidepressants

Nerve stimulation plus physical rehabilitation may boost recovery of arm and hand function

New sequencing tool speeds up SARS-CoV-2 outbreak response and informs treatment

CT scans may be better first step for evaluating chest pain

Virtual relaxation therapy reduces distress in end-of-life care

CRISPR revolutionized: New method edits genes directly in the body

Early whole blood transfusion boosts survival in trauma patients

Study paves the way for improving personalized treatment of patients with glioblastoma

Pioneering repository aims to raise visibility and awareness about people with mental illnesses

Scientists coax a deadly bacterium to destroy itself from the inside out

Scientists uncover a way to "hack" neurons' internal clocks to speed up brain cell development

Immunocompromised patients show prolonged SARS-CoV-2 infection and unique mutations

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

AI-based applications for personalized cancer medicine and related regulatory challenges: An overview

Ketamine therapy for mental health a ‘wild West’ for doctors and patients

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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