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Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

A new view of SARS-CoV-2 genome structure

Researchers performed DMS mutational profiling with sequencing and DREEM clustering to determine the SARS-CoV-2 RNA secondary structure.

8 Mar 2022

Insurance status and residential zip codes linked with survival among breast cancer patients

Recent findings published in JAMA Oncology found that individual insurance status and residential zip codes were correlated with overall survival among women with early hormone receptor-positive breast cancer.

8 Mar 2022

Researchers develop scoring tools to determine hospitalization and mortality risk in COVID-19 patients

Researchers conducted a large retrospective study on a cohort of severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 patients, developing and validating a simple and precise scoring tool to risk stratify COVID-19 ambulatory and emergency department patients for subsequent hospitalizations and mortalities.

8 Mar 2022

Higher SARS-CoV-2 load in morning-collected samples

In a recent study posted to the medRxiv* preprint server, researchers identified that morning-collected nasal and saliva samples yielded better detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially in tests with low to moderate analytical sensitivity.

8 Mar 2022

Bacterial coinfection pervasiveness and antibiotic use in COVID-19 patients

In a recent study posted to the medRxiv* pre-print server, researchers conducted a meta-analysis to determine the bacterial coinfection and antibiotic usage prevalence in coronavirus disease 2019 (COVID-19) patients.

7 Mar 2022

Clinical decision support system may help improve cardiovascular health in patients with severe mental illness

In a new study, researchers demonstrated that they can significantly lower cardiovascular risk for patients with severe mental illness (SMI) by using a clinical decision support system that prompts doctors to provide individualized informational handouts about a patient's cardiovascular risk and treatment recommendations.

7 Mar 2022

French study shows COVID vaccine efficacy 94% against severe outcomes

A recent paper published on the medRxiv preprint server utilized data from three national databases containing an abundance of information on Covid-19 screening (SI-DEP), vaccination (VAC-SI), and hospitalizations (SI-VIC) in France to provide additional perspectives on vaccine effectiveness and its evolution over the year 2021 in the French context.

7 Mar 2022

World's largest genetic study reveals fresh details about severe Covid-19

The world's largest study of the genetics of critical Covid-19, involving more than 57,000 people, has revealed fresh details about some of the biological mechanisms behind the severe form of the disease.

7 Mar 2022

SARS-CoV-2 breakthrough infection leads to distinct neutralizing antibody response

Scientists hypothesize that antibody-specific responses vary during vaccine breakthrough infections in a variant-specific manner.

7 Mar 2022

Evaluating SARS-CoV-2 IgG seroprevalence in the Okinawa islands of Japan

Scientists reveal that the pattern of the COVID-19 pandemic may significantly differ between the main island and remote islands of Japan.

7 Mar 2022

Researchers find considerable differences in performance between different artificial heart valves

Researchers at Karolinska Institutet in Sweden have studied long-term morbidity and mortality in individuals who have had different models of biological heart valves implanted.

7 Mar 2022

Severity of COVID-19 cases in the months of Alpha variant predominance compared to the Delta variant

The findings of the study demonstrated the higher occurrence of more severe cases during the predominance of the Alpha variant as compared to the Delta wave after adjusting the regression model for effects like age and status of vaccination.

7 Mar 2022

Study explores differentially expressed immune genes for COVID-19 patient stratification

In a new study, researchers determined the transcriptional signatures associated with the severity of COVID-19.

7 Mar 2022

Differences in observed COVID-19 case fatality rates between different racial groups in the US

Researchers assessed the disparities in COVID-19 case fatality rates among different races in the United States.

7 Mar 2022

Study examines whether knowledge of virus-neutralizing antibody titer impacted wellness decision-making

Researchers evaluated the impact of virus-neutralizing antibody titers against SARS-CoV-2 knowledge on deciding the timing of booster vaccination and social behavior.

7 Mar 2022

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

A new study discusses the outcomes of idiopathic pulmonary fibrosis patients with confirmed SARS-CoV-2 infection.

6 Mar 2022

Diabetes and the mTOR pathway in COVID-19 patients

A new study discusses the possible etiopathogenetic mechanisms associated with diabetes that could enhance the severity of COVID-19.

6 Mar 2022

Myocarditis and pericarditis in COVID-19 vaccine recipients

A new study provides valuable evidence towards this end, using surveillance data to provide the best estimates of these outcomes.

6 Mar 2022

Mortality News and Research

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

A new view of SARS-CoV-2 genome structure

Insurance status and residential zip codes linked with survival among breast cancer patients

Researchers develop scoring tools to determine hospitalization and mortality risk in COVID-19 patients

Higher SARS-CoV-2 load in morning-collected samples

Bacterial coinfection pervasiveness and antibiotic use in COVID-19 patients

Clinical decision support system may help improve cardiovascular health in patients with severe mental illness

French study shows COVID vaccine efficacy 94% against severe outcomes

World's largest genetic study reveals fresh details about severe Covid-19

SARS-CoV-2 breakthrough infection leads to distinct neutralizing antibody response

Evaluating SARS-CoV-2 IgG seroprevalence in the Okinawa islands of Japan

Researchers find considerable differences in performance between different artificial heart valves

Severity of COVID-19 cases in the months of Alpha variant predominance compared to the Delta variant

Study explores differentially expressed immune genes for COVID-19 patient stratification

Differences in observed COVID-19 case fatality rates between different racial groups in the US

Study examines whether knowledge of virus-neutralizing antibody titer impacted wellness decision-making

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Diabetes and the mTOR pathway in COVID-19 patients

Myocarditis and pericarditis in COVID-19 vaccine recipients

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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