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Comet supercomputer performs complex calculations on receptor sequence data from human T cells

While researchers around the world race to develop an effective and safe COVID-19 vaccine, a team from the San Diego Supercomputer Center (SDSC) at UC San Diego contributed to a study led by Vanderbilt Vaccine Center of Vanderbilt University Medical Center (VUMC) on T cell receptors, which play a vital role in alerting the adaptive immune system to mount an attack on invading foreign pathogens including the Coronavirus SARS-CoV-2.

8 Oct 2020

Vitamin D deficiency may predict COVID-19 seroconversion

A recent study published on the preprint server medRxiv* in October 2020 reports the potential contribution of vitamin D deficiency to an increased risk of COVID-19 in a subset of health care workers in the UK.

8 Oct 2020

SARS-CoV-2 infection analysis could help fight against COVID-19

Researchers in the United States has provided a detailed catalog of the interactions that occur between host cell proteins and RNA and the RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the course of infection.

7 Oct 2020

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

7 Oct 2020

Researchers hope to develop an effective COVID-19 vaccine using bovine adenovirus

A researcher in Penn State's College of Agricultural Sciences is part of a team of scientists working to develop a unique COVID-19 vaccine that uses a bovine adenovirus as a safe and effective delivery vehicle.

7 Oct 2020

Endocannabinoids in the body can help fight intestinal infections

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.

7 Oct 2020

Research elucidates the molecular mechanism of lentiviral cross-species transmission

Humans are exposed continuously to the menace of viral diseases such as those caused by the Ebola virus, Zika virus and coronaviruses. Such emerging/re-emerging viral outbreaks can be triggered by cross-species viral transmission from wild animals to humans.

7 Oct 2020

People infected with other types of coronaviruses may have less severe COVID-19 infection

Being previously infected with a coronaviruses that cause the "common cold" may decrease the severity of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infections, according to results of a new study

7 Oct 2020

Study may explain why cannabis plant can reduce symptoms of various bowel conditions

7 Oct 2020

Study shows COVID-19 vulnerability increases exponentially with age

Aging-US recently published "From Causes of Aging to Death from COVID-19" by Blagosklonny et al. which reported that COVID-19 is not deadly early in life, but mortality increases exponentially with age - which is the strongest predictor of mortality.

7 Oct 2020

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

A recent paper published in the preprint server medRxiv in September 2020 discusses the “clinically relevant variation in the expression of COVID-19-related genes”, which is associated with the host and environmental factors, as well as host genetic factors.

6 Oct 2020

Eli Lilly's LY-CoV555 antibody shows potential as COVID-19 treatment

Researchers in the United States and Canada have discovered a monoclonal antibody that potently neutralizes severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

5 Oct 2020

New findings could improve investigation of T cell response to COVID-19

Researchers in the United States have made an important discovery about the processing and presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral peptides that provides a better understanding of the immune response to coronavirus disease 2019 (COVID-19) and may help facilitate the design of improved vaccines.

5 Oct 2020

Less than 10% of US adults have SARS-CoV-2 antibodies

A new study by researchers at Stanford University and Ascend Clinical Laboratory and published in the journal The Lancet in September 2020 reports the prevalence of antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in a dialysis patient population in the US.

5 Oct 2020

Will COVID-19 become a seasonal virus?

In this interview, Dr. Hadi Yassine and Dr. Hassan Zaraket speak about their research into whether COVID-19 will become a seasonal virus.

5 Oct 2020

Another study finds cross-reactivity T cell responses against SARS-CoV-2

Using ELISpot and proliferation assays, researchers show strong responses in SARS-CoV-2 infected patients, but not so much in negative samples. However, there may be cross-reactive T cell responses from other human coronaviruses.

5 Oct 2020

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

A large group of researchers from the United States reported developing an amplification-free CRISPR-based mobile phone assay for direct detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from nasal swabs. Their state-of-the-art paper is currently available on the medRxiv* preprint server.

4 Oct 2020

immunity News and Research

Comet supercomputer performs complex calculations on receptor sequence data from human T cells

Vitamin D deficiency may predict COVID-19 seroconversion

SARS-CoV-2 infection analysis could help fight against COVID-19

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

Researchers hope to develop an effective COVID-19 vaccine using bovine adenovirus

Endocannabinoids in the body can help fight intestinal infections

Research elucidates the molecular mechanism of lentiviral cross-species transmission

People infected with other types of coronaviruses may have less severe COVID-19 infection

Study may explain why cannabis plant can reduce symptoms of various bowel conditions

Study shows COVID-19 vulnerability increases exponentially with age

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

Eli Lilly's LY-CoV555 antibody shows potential as COVID-19 treatment

New findings could improve investigation of T cell response to COVID-19

Less than 10% of US adults have SARS-CoV-2 antibodies

Will COVID-19 become a seasonal virus?

Another study finds cross-reactivity T cell responses against SARS-CoV-2

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

New multiplexed test with a low-cost sensor may enable at-home COVID diagnosis

Calibr's novel 'switchable' CAR-T cell therapy granted FDA's Fast Track designation

Study reveals how ILCs develop, adapt, specialize in specific tissue environments

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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