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International consortium to provide recommendations for understanding PRO data in cancer clinical trials

An international multidisciplinary consortium, co-led by the European Organisation for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has been convened to generate recommendations to standardize the use, analysis, and interpretation of patient-reported outcome (PRO) data in cancer clinical trials.

18 Feb 2021

Study shows how the brains of overweight people work differently from those of healthy weight

A research group from Mind, Brain, and Behaviour Research Centre (CIMCYC) of the University of Granada (UGR) has been studying the issue of excess weight from a neuroscientific perspective for many years, to determine the precise role played by the brain.

18 Feb 2021

New automated system may reduce opioid misuse

After more than 1,000 orthopedic procedures at a city health system, roughly 61 percent of the opioids prescribed to patients went unused, according to new research.

18 Feb 2021

SARS-CoV-2 variants of concern drive up infections by 15-40 percent in Germany

As the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to distress worldwide, new variants are emerging that threaten the possibility of containment by current vaccines or therapeutic antibodies.

18 Feb 2021

New insights on structural biology may help design more efficient antibodies

In structural biology, some molecules are so unusual they can only be captured with a unique set of tools.

18 Feb 2021

Scientists successfully restore circadian function in the liver of arrhythmic mice

Circadian clocks, which regulate the metabolic functions of all living beings over a period of about 24 hours, are one of the most fundamental biological mechanisms.

18 Feb 2021

New collaborative project to study the complex roles of lipids in health, disease

A University of Minnesota-Mayo Clinic partnership has joined with the Zooniverse citizen scientist platform and the Francis Crick Institute in London to leverage world-leading expertise in microscope imaging with the power of citizen science to study the relationship between structure and function in biology to better understand health and disease.

17 Feb 2021

Advancements in DNA vaccines against COVID-19

The rapid spread of the pathogen and the increasing number of cases highlight the need for an effective and safe vaccine. As vaccination efforts roll out in many countries, new types of vaccines, like deoxyribonucleic acid (DNA) vaccines, are under research..

17 Feb 2021

Study: Cognitive SuperAgers resist protein tangles that lead to Alzheimer’s disease

A new Northwestern Medicine study showed cognitive SuperAgers have resistance to the development of fibrous tangles in a brain region related to memory and which are known to be markers of Alzheimer's disease.

17 Feb 2021

New 3D imaging technique helps detect breast cancer, COVID-19, other diseases

A research team led by UMass Lowell is pioneering a new 3D imaging technique to better detect breast cancer and other diseases, including COVID-19.

17 Feb 2021

New study sheds light on potential pathophysiological mechanism underlying delirium

Delirium, a common syndrome among older adults, particularly in those who have recently undergone surgery, critically ill patients in the ICU, and in older patients with multiple health issues, is a form of acute confusion that is characterized by poor attention, disorientation, impaired memory, delusions, and abrupt changes in mood and behavior.

17 Feb 2021

Study sheds light on pathological characteristics behind sudden cardiac death

Nearly a half-million people a year die from sudden cardiac death (SCD) in the U.S. -- the result of malfunctions in the heart's electrical system.

17 Feb 2021

Sensor-based asthma inhalers can benefit pediatric asthma patients

Sensor-based inhalers integrated into health care providers' clinical workflows may help improve medication adherence and support children with asthma - and their families - to more effectively manage this condition, according to a new Northwestern and Lurie Children's study published in Pediatrics.

17 Feb 2021

GDP significantly associated with greater COVID-19 vaccine distribution

ccording to a report published by the Bureau of Economic Analysis, the world's gross domestic product (GDP) fell by 4.6% in 2020. As per WHO estimates, at least 65% of the world population should be vaccinated to contain the virus's spread and achieve herd immunity.

17 Feb 2021

Convalescent plasma shows CD8+ T cell responses to SARS-CoV-2 variants

Researchers in the United States have conducted a study suggesting that individuals who have recovered from or been vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) should maintain effective CD8+ T-cell responses against the major variants that have recently emerged.

17 Feb 2021

Opioid supply-controlling policies may have unintended consequences, finds study

In response to the increase in opioid overdose deaths in the United States, many states have implemented supply-controlling and harm-reduction policy measures aimed at reducing those deaths.

17 Feb 2021

Study: Gynecologists have a negative attitude towards clitoral reconstruction after female genital cutting

"Gynecologists in Sweden are a very polarized group regarding clitoral reconstruction, and our study is one of very few on the subject," says Malin Jordal, researcher and senior lecturer in caring sciences at University of Gävle.

17 Feb 2021

Researchers find a way to improve deletion efficiency of new genome-editing tool

CRISPR deletion (CRISPR-del) is a new genome editing tool that can delete or cut out certain pieces of DNA in living cells with surgical precision.

17 Feb 2021

Using complementary disinfection strategies to make swimming pools safer

Swimming in indoor or outdoor pools is a healthy form of exercise and recreation for many people. However, studies have linked compounds that arise from chlorine disinfection of the pools to respiratory problems, including asthma, in avid swimmers.

17 Feb 2021

Nasal antiviral blocks SARS-CoV-2 transmission in ferrets

A nasal antiviral created by researchers at Columbia University Vagelos College of Physicians and Surgeons blocked transmission of SARS-CoV-2 in ferrets, suggesting the nasal spray also may prevent infection in people exposed to the new coronavirus, including recent variants.

17 Feb 2021

Research News and Research

International consortium to provide recommendations for understanding PRO data in cancer clinical trials

Study shows how the brains of overweight people work differently from those of healthy weight

New automated system may reduce opioid misuse

SARS-CoV-2 variants of concern drive up infections by 15-40 percent in Germany

New insights on structural biology may help design more efficient antibodies

Scientists successfully restore circadian function in the liver of arrhythmic mice

New collaborative project to study the complex roles of lipids in health, disease

Advancements in DNA vaccines against COVID-19

Study: Cognitive SuperAgers resist protein tangles that lead to Alzheimer’s disease

New 3D imaging technique helps detect breast cancer, COVID-19, other diseases

New study sheds light on potential pathophysiological mechanism underlying delirium

Study sheds light on pathological characteristics behind sudden cardiac death

Sensor-based asthma inhalers can benefit pediatric asthma patients

GDP significantly associated with greater COVID-19 vaccine distribution

Convalescent plasma shows CD8+ T cell responses to SARS-CoV-2 variants

Opioid supply-controlling policies may have unintended consequences, finds study

Study: Gynecologists have a negative attitude towards clitoral reconstruction after female genital cutting

Researchers find a way to improve deletion efficiency of new genome-editing tool

Using complementary disinfection strategies to make swimming pools safer

Nasal antiviral blocks SARS-CoV-2 transmission in ferrets

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