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Understanding asthma: The surprising influence of gut bacteria

The role of specific gut microbes in asthma.

15 Nov 2023

Study reveals mechanisms underlying non-suppressible HIV viremia

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

14 Nov 2023

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA - loops of DNA found outside of regular chromosomes - are twice as likely to relapse and three times as likely to die within five years of diagnosis.

14 Nov 2023

Does cannabis use impact the risk of glaucoma? New study investigates

The study in Scientific Reports finds no significant association between cannabis use and the risk of primary open-angle glaucoma, challenging the notion that cannabis could influence intraocular pressure and glaucoma risk.

14 Nov 2023

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

The COVID-19 disease, due to infection with the SARS-CoV2 virus, became an international pandemic in 2020. To date, more than 770 million people have suffered from the disease and nearly 7 million of them have lost their life.

14 Nov 2023

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

14 Nov 2023

Genetic test for antidepressants could save millions and improve patient outcomes

A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research from the University of British Columbia.

14 Nov 2023

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

13 Nov 2023

Study shows environment's pivotal role in healthy aging and disease prevention

Study explores new geroscience tools for studying the impact of environmental factors on aging, aiming to delay age-related diseases and disabilities. It highlights how non-genetic factors, like environmental toxins and socio-economic conditions, significantly influence aging and health outcomes.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Recaticimab injection every 1-3 months may safely lower bad cholesterol

A new PCSK9 inhibitor (recaticimab) injected every one to three months may work safely and provide more flexible dosing to lower cholesterol, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Single injection of new medication effectively eliminates Lp(a) for nearly one year

In the first human trial of a new therapeutic, a single injection of lepodisiran reduced levels of lipoprotein(a), or Lp(a), to undetectable levels for nearly one year, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Transforming brain research with AI and machine learning

Using machine learning, researchers are able to use data from the brain to glean deeper insights and apply this new knowledge in clinical settings.

13 Nov 2023

Researchers identify specific genes, brain regions, and cognitive features associated with depression

In studies that examine the depressed brain, researchers were able to identify specific genes, molecules, brain regions, and cognitive features that are associated with the disorder.

13 Nov 2023

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Crown Bioscience, a global contract research organization (CRO) and JSR Life Sciences company, today announced the launch of its ground-breaking service offering, OrganoidXploreTM.

13 Nov 2023

Food allergies may be linked to increased cardiovascular death risk, study finds

Sensitivity to common food allergens such as dairy and peanuts could be an important and previously unappreciated cause of heart disease, new research suggests – and the increased risk for cardiovascular death includes people without obvious food allergies.

13 Nov 2023

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

In a comprehensive multi-ancestry GWAS meta-analysis, researchers identified 451 risk variants for prostate cancer, including 187 new variants, demonstrating the utility of such studies across diverse populations. This analysis not only increased understanding of genetic risk factors but also differentiated between aggressive and non-aggressive prostate cancer types, underscoring the potential of genetic risk scoring in guiding screening and early detection strategies.

12 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Maternal metabolic conditions linked to children's neurodevelopmental risks, study shows

Study investigates how maternal metabolic conditions like pregestational diabetes, gestational diabetes, and obesity mediate the risk of neurodevelopmental conditions in children. It highlights the significant role of obstetric and neonatal complications in this relationship, emphasizing the need for managing these complications to mitigate children's risk of developing conditions like ADHD and autism.

12 Nov 2023

Genetic News and Research

Understanding asthma: The surprising influence of gut bacteria

Study reveals mechanisms underlying non-suppressible HIV viremia

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

Does cannabis use impact the risk of glaucoma? New study investigates

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Genetic test for antidepressants could save millions and improve patient outcomes

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Study shows environment's pivotal role in healthy aging and disease prevention

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Recaticimab injection every 1-3 months may safely lower bad cholesterol

Single injection of new medication effectively eliminates Lp(a) for nearly one year

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

Transforming brain research with AI and machine learning

Researchers identify specific genes, brain regions, and cognitive features associated with depression

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Food allergies may be linked to increased cardiovascular death risk, study finds

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

UCI researchers discover gene critical for muscle repair

Maternal metabolic conditions linked to children's neurodevelopmental risks, study shows

Genetics & Genomics - Second Edition eBook

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