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Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Spanish researchers use cisgenic engineering to create nutrient-packed tomatoes with higher levels of flavonoids and branched-chain amino acids, providing potential benefits for those on plant-based diets. The study shows promise for enhancing nutritional content in other crops, addressing malnutrition and health deficiencies.

27 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Small and precise: These are the ideal characteristics for CRISPR systems, the Nobel-prize winning technology used to edit nucleic acids like RNA and DNA.

27 Sep 2023

Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

Mutations on a key SARS-CoV-2 viral protein are linked to extreme immune responses and could offer a novel vaccine target.

27 Sep 2023

UKHSA donates advanced genomic surveillance equipment to CARPHA

This is a significant stride towards strengthening global genomic surveillance to track new variants and pathogens of pandemic and epidemic potential.

27 Sep 2023

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Rice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique in rodents, and their findings suggest that the efficiency of gene delivery improves within each targeted site when more sites are opened.

27 Sep 2023

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

An astounding 30% of Americans currently have metabolic dysfunction-associated steatotic liver disease, or MASLD, which is formerly known as nonalcoholic fatty liver disease, or NAFLD.

27 Sep 2023

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Researchers utilize imaging findings to elucidate how Alzheimer's dementia can present considerable variations depending on the sex of the individual.

27 Sep 2023

Arrayed CRISPR Screening for Revolutionizing Target Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Kuenzel, Associate Director in the Functional Genomics department at AstraZeneca about the application of arrayed CRISPR screening for target identification and more.

From Society for Laboratory Automation and Screening (SLAS) 27 Sep 2023

Unions between close relatives may increase the risk of common diseases, study finds

A new study finds that consanguinity – unions between close relatives - may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD).

26 Sep 2023

Three new projects launched to map neuronal connections in the mouse and macaque brains

A complete map of all the connections in an entire mammalian brain may be in sight. Allen Institute researchers have just launched three new projects to construct large, detailed maps of neuronal connections in sections of the mouse and macaque brains, with an eye toward creating full wiring diagrams of these animals' brains in the future.

26 Sep 2023

Study finds link between deforestation, mosquito biodiversity, and virus prevalence

How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Scientists from Charité – Universitätsmedizin Berlin in cooperation with the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) have now described one piece of that puzzle in the journal "eLife", showing that the destruction of tropical rainforests harms the diversity of mosquito species.

26 Sep 2023

Key player in ovarian cancer may have implications for PCOS

Researchers explore the involvement and altered expression of BBOX1-AS1 and microRNA-19b in polycystic ovary syndrome.

26 Sep 2023

Could next-generation antimicrobial agents act as an alternative to standard antibiotics?

Next-generation antimicrobial agents (NGAs) as a potential alternative to standard antibiotics

26 Sep 2023

Senescent macrophages in the lung promote tumor growth, study finds

Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors.

25 Sep 2023

New method for multiancestry polygenic prediction holds promise for reducing health care disparities

A team led by researchers at Johns Hopkins Bloomberg School of Public Health and the National Cancer Institute has developed a new algorithm for genetic risk-scoring for major diseases across diverse ancestry populations that holds promise for reducing health care disparities.

25 Sep 2023

One gene variant could be a shield against severe COVID-19 lung damage

Researchers identify a specific genetic variant, rs2204985, linked to less severe lung involvement and a stronger immune response in COVID-19 patients with severe pneumonia. The study suggests that understanding this genetic marker could help identify high-risk individuals and enhance strategies for prevention and treatment.

25 Sep 2023

Research uncovers a link between antiviral drug for COVID-19 and SARS-CoV-2 mutations

Researchers at the Francis Crick Institute, the University of Cambridge, Imperial College London, the University of Liverpool, the University of Cape Town and UKHSA have uncovered a link between an antiviral drug for COVID-19 infections called molnupiravir and a pattern of mutations in the SARS-CoV-2 virus.

25 Sep 2023

Do environmental and occupational factors influence semen quality?

New research sheds light on how environmental and occupational factors impact male fertility, revealing that proximity to power lines may enhance semen quality while living near chemical factories could be detrimental. The study emphasizes the need for a deeper understanding of these factors in the context of rising infertility rates.

25 Sep 2023

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown. It is not clear, however, whether these mutated viruses pose an increased risk to patients or are able to evade the vaccine.

25 Sep 2023

Genetic News and Research

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Blocking Notch signaling pathway could reverse age-related bone loss

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

UKHSA donates advanced genomic surveillance equipment to CARPHA

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Unions between close relatives may increase the risk of common diseases, study finds

Three new projects launched to map neuronal connections in the mouse and macaque brains

Study finds link between deforestation, mosquito biodiversity, and virus prevalence

Key player in ovarian cancer may have implications for PCOS

Could next-generation antimicrobial agents act as an alternative to standard antibiotics?

Senescent macrophages in the lung promote tumor growth, study finds

New method for multiancestry polygenic prediction holds promise for reducing health care disparities

One gene variant could be a shield against severe COVID-19 lung damage

Research uncovers a link between antiviral drug for COVID-19 and SARS-CoV-2 mutations

Do environmental and occupational factors influence semen quality?

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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