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Discovery may lead to potential new therapeutic approach to eradicate blood cancers

An international team of scientists, headed by researchers at UC San Diego School of Medicine and UC San Diego Moores Cancer Center, report that decreases in a specific group of proteins trigger changes in the cancer microenvironment that accelerate growth and development of therapy-resistant cancer stem cells (CSCs).

1 Dec 2015

International telepathology consultations can improve patient care in China, study finds

International telepathology consultations can significantly improve patient care, according to a new study by UPMC and KingMed Diagnostics researchers. Their review of more than 1,500 pathology cases submitted electronically to UPMC over three years found that consultation with UPMC pathologists resulted in significantly altered treatment plans for more than half of the cases in which a patient's primary diagnosis had been provided from referring hospitals in China.

1 Dec 2015

$Reduced bone mass puts critically ill patients at greater risk for fractures$

Reduced bone mass puts critically ill patients at greater risk for fractures

One year after being hospitalized in intensive care, patients have reduced bone mass that puts them at greater risk for fractures, according to a new study published online ahead of print in the American Journal of Respiratory and Critical Care Medicine.

1 Dec 2015

Researchers develop more precise way to control differentiation of stem cells into bone cells

Researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences and The Wyss Institute for Biologically Inspired Engineering have developed a new, more precise way to control the differentiation of stem cells into bone cells.

1 Dec 2015

FDA grants approval for Empliciti (elotuzumab) to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Empliciti (elotuzumab) in combination with two other therapies to treat people with multiple myeloma who have received one to three prior medications.

30 Nov 2015

Researchers discover drug target and genetic pathway for graft-versus-host disease

A Seattle Children's Research Institute lab has discovered a genetic pathway that can be targeted with existing drugs to prevent graft-versus-host disease (GVHD), a common and deadly complication of bone marrow transplants.

30 Nov 2015

Testosterone treatment can benefit men with Type 2 diabetes

Men with Type 2 diabetes who have low testosterone levels can benefit significantly from testosterone treatment.

30 Nov 2015

Research shows how various organ systems change and adapt in ultra-distance runners

Using a mobile MRI truck, researchers followed runners for 4,500 kilometers through Europe to study the physical limits and adaptation of athletes over a 64-day period, according to a study presented today at the annual meeting of the Radiological Society of North America.

30 Nov 2015

Six-month markers predict long-term cGVHD outcomes

Researchers have identified measures early in the course of chronic graft-versus-host disease that predict long-term prognosis in haematopoietic cell transplantation recipients.

27 Nov 2015

TransLUMINAL-B project kicked off to study luminal breast cancers

Following a kick-off meeting, the TransLUMINAL-B project, which is being led by Charité -- Universitätsmedizin Berlin, is now officially underway. Over the next three years, researchers involved in the project will study the process of metastasis formation and the role of malignant cells, which accumulate in the blood and bone marrow of patients with certain types of breast cancer.

26 Nov 2015

Orthopedic surgeon creates world's first internal bone-lengthening device for young children

An orthopedic surgeon is creating the world's first implantation device that can lengthen the bones of young children internally. The inventor, a physician at Texas Tech University Health Sciences Center El Paso, expects the device will lead to fewer infections and less pain, making the bone-lengthening process more bearable for children.

25 Nov 2015

SkylineDx's MMprofiler receives CE-IVD certification

SkylineDx, today announced they have received CE-IVD registration from the European Competent Authority (Ministry of Health) for the MMprofiler, the company's prognostic test to determine the level of risk of a patient with multiple myeloma (MM).

25 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

Vitamin D supplements have no effect on frequency and severity of colds in asthma patients

Vitamin D supplements do not reduce the number or severity of colds in asthma patients, according to a new study published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

25 Nov 2015

Novartis announces EC approval of Cosentyx for treatment of ankylosing spondylitis, psoriatic arthritis

Novartis announced today that the European Commission has approved Cosentyx (secukinumab) for the treatment of people living with ankylosing spondylitis (AS) and psoriatic arthritis (PsA). For AS, this is the first new treatment advance in 16 years since the development of the current standard of care, anti-tumor necrosis factor (anti-TNF) therapy.

25 Nov 2015

Fat cells produced from bone marrow may be linked to chronic diseases

Researchers at the University of Colorado Anschutz Medical Campus have found that fat cells produced by stem cells from the bone marrow may be linked to chronic illnesses like diabetes, cardiovascular disease, kidney disease and some cancers.

25 Nov 2015

Microgravity inhibits regenerative and differentiation potential of embryonic stem cells

A study performed on the NASA Space Shuttle Discovery showed that exposure of mouse embryonic stem cells (mESCs) to microgravity inhibited their ability to differentiate and generate most cell lineages, needed for the development of bone, muscle, the immune system, and other organs and tissues.

24 Nov 2015

New mathematical model forecasts metastatic breast cancer survival rates

USC researchers have developed a mathematical model to forecast metastatic breast cancer survival rates using techniques usually reserved for weather prediction, financial forecasting and surfing the Web.

24 Nov 2015

Leukemia & Lymphoma Society applauds FDA's recent approval of two new multiple myeloma drugs

The Leukemia & Lymphoma Society applauds the FDA's recent approval of two new drugs -- daratumumab and ixazomib -- to treat patients with relapsed multiple myeloma. These therapies are the latest in a growing arsenal to fight this blood cancer that impacts nearly 100,000 patients in the U.S. Advances in treatments for many different types of blood cancers are happening with dizzying speed and these two approvals in just one week are the latest evidence of this phenomenon.

23 Nov 2015

Men with prostate cancer get stronger bones from playing football

Men with prostate cancer run the risk of brittle bones as a side-effect of their treatment. But one hour's football training a few times a week counters many of the negative effects of the treatment, according to University of Copenhagen scientists.

23 Nov 2015

Bone News and Research

Discovery may lead to potential new therapeutic approach to eradicate blood cancers

International telepathology consultations can improve patient care in China, study finds

Reduced bone mass puts critically ill patients at greater risk for fractures

Researchers develop more precise way to control differentiation of stem cells into bone cells

FDA grants approval for Empliciti (elotuzumab) to treat patients with multiple myeloma

Researchers discover drug target and genetic pathway for graft-versus-host disease

Testosterone treatment can benefit men with Type 2 diabetes

Research shows how various organ systems change and adapt in ultra-distance runners

Six-month markers predict long-term cGVHD outcomes

TransLUMINAL-B project kicked off to study luminal breast cancers

Orthopedic surgeon creates world's first internal bone-lengthening device for young children

SkylineDx's MMprofiler receives CE-IVD certification

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

Vitamin D supplements have no effect on frequency and severity of colds in asthma patients

Novartis announces EC approval of Cosentyx for treatment of ankylosing spondylitis, psoriatic arthritis

Fat cells produced from bone marrow may be linked to chronic diseases

Microgravity inhibits regenerative and differentiation potential of embryonic stem cells

New mathematical model forecasts metastatic breast cancer survival rates

Leukemia & Lymphoma Society applauds FDA's recent approval of two new multiple myeloma drugs

Men with prostate cancer get stronger bones from playing football

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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