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Precision medicine doubles progression-free survival in young cancer patients

Cancer is the leading cause of disease-related death in children in most developed countries, and at least a quarter of these patients are diagnosed with aggressive high-risk or relapsed cancers, with an expected five-year survival rate of less than 30%.

31 May 2024

Study challenges use of in-hospital mortality as sepsis quality metric for safety-net hospitals

Sepsis is a leading cause of death and disability and a key target of state and federal quality measures for hospitals.

31 May 2024

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people worldwide.

31 May 2024

Mediterranean diet linked to lower mortality risk in women

Investigators from Brigham and Women's Hospital identified and assessed underlying mechanisms that may explain the Mediterranean diet's 23 percent reduction in all-cause mortality risk for American women.

31 May 2024

Radiomics imaging analysis can effectively forecast hearing status of vestibular schwannoma patients

A recent study demonstrates that radiomics imaging analysis can effectively forecast the hearing status of patients with vestibular schwannoma patients.

31 May 2024

New research center delves into ubiquitin's role in cancer

The German Research Foundation (DFG) has now approved a new Collaborative Research Centre in the search for innovative therapies against cancer: Researchers from the Technical University of Munich (TUM), Goethe University Frankfurt and Julius-Maximilians-Universität Würzburg (JMU) have joined forces for this purpose.

31 May 2024

New mobile app shows dramatic success in smoking cessation

A new mobile application, developed under the leadership of researchers from the University of Oulu, Finland, has proven to be an effective aid for long-term smokers attempting to quit.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

An international study led by the Hospital del Mar Medical Research Institute, in collaboration with researchers from the Neuropsychopharmacology Group at the University of the Basque Country (UPV/EHU) and researchers from the CIBER of Mental Health (CIBERSAM), and published in Nature Communications, may facilitate the creation of new personalized treatments for people diagnosed with schizophrenia.

30 May 2024

Thailand grapples with colorectal cancer epidemic

According to research led by Prof. Varut Lohsiriwat, Professor of Surgery, Division of General Surgery (Section of Colorectal Surgery) of Siriraj Hospital, at Mahidol University, CRC is the third most common cancer in Thailand, accounting for 11% of the cancer burden. It is the only malignancy with an increased incidence in both genders in the country.

30 May 2024

Dana-Farber study exposes hidden disparities in cancer care experiences

Four teams of Dana-Farber Cancer Institute investigators have found that people experience discrimination and bias in different ways and in more realms of cancer care than previously understood.

30 May 2024

Cervix-on-a-Chip: A breakthrough model for studying women's health

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

30 May 2024

Three-year study shows lingering effects of COVID-19

New findings on long COVID - long-term effects on health experienced by many who have had COVID-19 - present a good-news, bad-news situation, according to a study at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

30 May 2024

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

A team of researchers from the Institute of Oncology of the University of Oviedo (IUOPA), the Josep Carreras leukemia Research Institute, the University of Barcelona and the Centre for Biomedical Research in Cancer Network (CIBERONC) have demonstrated that some childhood leukemia originate during embryonic development, although they do not manifest after a few months after birth.

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

A nutrition screener developed for improving access to federal food benefits

Researchers from The Possibilities Project and Clinical Futures at Children's Hospital of Philadelphia (CHOP) developed, implemented and successfully tested a nutrition screener to improve access to healthy resources for families eligible for federally funded food benefits.

30 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Memory decline reported by patients and partners may signal early Alzheimer's changes

A new study adds further evidence that when a patient or family member notices signs of persistent memory loss, it's important to speak with a doctor.

30 May 2024

Statins may block an inflammation pathway involved in the development of cancer

A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals that statins - commonly used cholesterol-lowering drugs - may block a particular pathway involved in the development of cancer that results from chronic inflammation.

30 May 2024

RCSI and Head Diagnostics collaborate to revolutionize multiple sclerosis assessment

RCSI has partnered with Head Diagnostics (Dublin, Ireland) on a clinical study to enhance the assessment and monitoring of Multiple Sclerosis (MS) through innovative technology.

30 May 2024