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Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

CHD5 has previously been proposed as a tumour suppressor, acting as a brake that prevents healthy cells from developing into cancer cells. But the part played by the protein in healthy tissue, and whether this role is important for its ability to counter tumour growth, has remained largely uncharted.

14 Aug 2013

Poly(lactic-co-glycolic acid) conduits suitable for sciatic nerve injury repair

The conventional method for repair of peripheral nerve injury is autogenous nerve grafting, but sources of autogenous nerve are limited. Furthermore, neurological deficits in the donor site and painful neuroma can occur following surgery.

14 Aug 2013

Research suggests Huntington's disease might begin in synapses

The synapses in the brain act as key communication points between approximately one hundred billion neurons. They form a complex network connecting various centres in the brain through electrical impulses. New research from Lund University suggests that it is precisely here, in the synapses, that Huntington's disease might begin.

13 Aug 2013

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Cedars-Sinai Medical Center has launched a Phase I clinical trial to study the safety and tolerability of an experimental immunization to treat Alzheimer's disease. The treatment is based on Copaxone (glatiramer acetate), a drug often prescribed to reduce the frequency of multiple sclerosis relapses.

13 Aug 2013

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body's source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study.

13 Aug 2013

Researchers explore potential of neural stem cells to repair brain damage

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body’s source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Researchers identify first disease gene for idiopathic focal epilepsy in childhood

More than 50 million people worldwide have epilepsy, with a third of these being children. The most common forms of epilepsy in children occur without any apparent trigger and only affect certain regions of the brain.

12 Aug 2013

Study of childhood epilepsies links two new genes to severe forms of disease

A genetic study of childhood epilepsies has linked two new genes to severe forms of disease and provides a novel strategy for identifying therapy targets. This study used a cutting-edge genetic technique, called exome sequencing, to search for new mutations that are not inherited.

12 Aug 2013

L-3-n-butylphthalide is potentially beneficial drug for treatment of vascular dementia

3-N-butylphthalide, a green botanical medicine, is a successfully synthesized and stable chemical drug used for the treatment of ischemic stroke that has independent intellectual property rights in China.

12 Aug 2013

Study reveals genetic mutations linked to Parkinson's may play a role in death of brain cells

Researchers have discovered how genetic mutations linked to Parkinson's disease might play a key role in the death of brain cells, potentially paving the way for the development of more effective drug treatments.

12 Aug 2013

Genetically engineered proteins may be promising new tool for mapping brain cell activity

Scientists used fruit flies to show for the first time that a new class of genetically engineered proteins can be used to watch nerve cell electrical activity in live brains. The results, published in Cell, suggest these proteins may be a promising new tool for mapping brain cell activity in multiple animals and for studying how neurological disorders disrupt normal nerve cell signaling.

9 Aug 2013

Person with type 2 diabetes may spend nearly $85,500 to treat the disease

A person with type 2 diabetes may spend an average of nearly $85,500 to treat the disease and its complications over his or her lifetime, reports a new study in the American Journal of Preventive Medicine.

9 Aug 2013

Penn State researchers find that protein changes can control gene functions

A Penn State-led research team has found that changes to proteins called histones, which are associated with DNA, can control whether or not a gene is allowed to function. The changes may be important in maintaining the genes' "expression potential" so that future cells behave as their parent cells did.

8 Aug 2013

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

New research suggests that treadmill training soon after a spinal cord injury can have long-lasting positive effects on recovery - as long as the training is accompanied by efforts to control inflammation in the lower spinal cord.

8 Aug 2013

Wiring diagram of retinal neurons: The first step toward mapping the human brain

The human brain has 100 billion neurons, connected to each other in networks that allow us to interpret the world around us, plan for the future, and control our actions and movements. MIT neuroscientist Sebastian Seung wants to map those networks, creating a wiring diagram of the brain that could help scientists learn how we each become our unique selves.

8 Aug 2013

Prevalence for major eye disease is higher in people with common sleep disorder

Researchers in Taiwan have discovered that people with sleep apnea are far more likely to develop glaucoma compared to those without the sleep condition. The results of this study, which is the first to calculate the risk of the disease among people with the sleep disorder following diagnosis, is published in this month's edition of Ophthalmology, the journal of the American Academy of Ophthalmology.

8 Aug 2013

Researchers develop nanoprobe technique to help treat fatal diseases more effectively

Researchers at the University of Southampton, in collaboration with colleagues at the University of Cambridge, have developed a technique to help treat fatal diseases more effectively.

8 Aug 2013

NIH-funded study of aquaporin proteins could hold clues to cataract

Researchers have achieved dynamic, atomic-scale views of a protein needed to maintain the transparency of the lens in the human eye. The work, funded in part by the National Institutes of Health, could lead to new insights and drugs for treating cataract and a variety of other health conditions.

6 Aug 2013

Study shows role of love hormone in promoting social and parental bonding

In a loud, crowded restaurant, having the ability to focus on the people and conversation at your own table is critical. Nerve cells in the brain face similar challenges in separating wanted messages from background chatter.

6 Aug 2013

Nerve News and Research

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

Poly(lactic-co-glycolic acid) conduits suitable for sciatic nerve injury repair

Research suggests Huntington's disease might begin in synapses

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Researchers explore potential of neural stem cells to repair brain damage

Researchers identify first disease gene for idiopathic focal epilepsy in childhood

Study of childhood epilepsies links two new genes to severe forms of disease

L-3-n-butylphthalide is potentially beneficial drug for treatment of vascular dementia

Study reveals genetic mutations linked to Parkinson's may play a role in death of brain cells

Genetically engineered proteins may be promising new tool for mapping brain cell activity

Person with type 2 diabetes may spend nearly $85,500 to treat the disease

Penn State researchers find that protein changes can control gene functions

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

Wiring diagram of retinal neurons: The first step toward mapping the human brain

Prevalence for major eye disease is higher in people with common sleep disorder

Researchers develop nanoprobe technique to help treat fatal diseases more effectively

NIH-funded study of aquaporin proteins could hold clues to cataract

Study shows role of love hormone in promoting social and parental bonding

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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