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New drug screening method may predict treatment options for patients with multiple myeloma

A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer. The process, developed by scientists at Washington University School of Medicine in St. Louis, also may aid patients with leukemia or lymphoma.

21 Nov 2015

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Ninlaro (ixazomib) in combination with two other therapies to treat people with multiple myeloma who have received at least one prior therapy.

21 Nov 2015

NICE recommends Xofigo (radium-223 dichloride) for patients with advanced prostate cancer

The National Institute for Health and Care Excellence today issued its Final Appraisal Determination (FAD) recommending Xofigo (radium-223 dichloride) for use on the NHS in England as an option for treating adult men, with hormone-relapsed prostate cancer, symptomatic bone metastases and no known visceral metastases, who have received previous docetaxel therapy.

20 Nov 2015

New type of drug may help bones heal faster, better

Inspired by amphibians like salamanders, researchers from the University of Southampton are developing a new type of drug that may help bones heal faster and better.

20 Nov 2015

MCG researchers explore how neurofibromatosis puts young patients at risk for cardiovascular disease

It's a fairly common genetic condition that can surface as a series of dark skin spots and result in a host of maladies from tumors to premature cardiovascular disease. Medical College of Georgia researchers hope their studies of how neurofibromatosis 1, or NF1, can dangerously thicken or thin blood vessel walls will one day help physicians better identify and treat these young patients at cardiovascular risk.

20 Nov 2015

Lilly, Merck expand oncology clinical trial collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced the extension of an existing collaboration to evaluate the safety and efficacy of the combination of Lilly's ALIMTA (pemetrexed for injection) and Merck's KEYTRUDA (pembrolizumab) in a pivotal Phase III study in first-line nonsquamous non-small cell lung cancer (NSCLC).

19 Nov 2015

INP achieves 80% survival rate in acute lymphoblastic leukemia patients

The National Institute of Pediatrics in Mexico, has achieved 80 percent survival rate in patients with acute lymphoblastic leukemia, a major oncological illness that affects children.

19 Nov 2015

Role of genetic predisposition in pediatric cancer patients

The most detailed analysis yet of the role germline mutations in genes associated with cancer predisposition play in the development of childhood cancer suggests that comprehensive genomic screening may be warranted on all pediatric cancer patients, not just those with a family history of cancer.

19 Nov 2015

New study finds link between obesity and surgery risk in orthopaedic trauma patients

A new study appearing in the November 18 issue of the Journal of Bone & Joint Surgery found a link between obesity and a higher risk for surgery in orthopaedic trauma patients. In addition, researchers found that patients with obesity had longer hospital stays and greater treatment costs. They were also more likely to be discharged to a care facility, rather than to home.

19 Nov 2015

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Advanced prostate cancer is a disease notoriously resistant to treatment. New research by scientists at Fred Hutchinson Cancer Research Center and the University of California, San Francisco sheds light on a new mode of drug resistance to emerging therapies in metastatic prostate cancer.

18 Nov 2015

Exercise, healthy lifestyle habits may cut prostate cancer risk by up to 68%

A study that tracked tens of thousands of midlife and older men for more than 20 years has found that vigorous exercise and other healthy lifestyle habits may cut their chances of developing a lethal type of prostate cancer by up to 68 percent.

18 Nov 2015

Matthew Teeter recognized with 2015 John Charles Polanyi Prize for research in joint replacement

Matthew Teeter, PhD, an assistant professor at Western University's Schulich School of Medicine & Dentistry and researcher at Lawson Health Research Institute, is a winner of the 2015 John Charles Polanyi Prize. The $20,000 award recognizes the excellence of Teeter's research in joint replacement.

18 Nov 2015

Bone protein can inhibit prostate cancer metastasis to bone

Scientists from Lawrence Livermore National Laboratory in collaboration with researchers from University of California campuses at Merced and Davis have found that a secreted protein predominantly expressed in bone inhibits prostate cancer metastasis to bone.

18 Nov 2015

USC discoveries propose promising method to eliminate pain associated with tooth decay

Dual discoveries at USC propose a promising method to regrow nonliving hard tissue, lessening or even eliminating pain associated with tooth decay, which the National Institutes of Health calls the most prevalent chronic disease.

18 Nov 2015

Viking submits IND application to FDA to conduct VK2809 Phase 2 study in patients with LDL-C and fatty liver disease

Viking Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on the development of novel, first-in-class or best-in-class therapies for metabolic and endocrine disorders, today announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration to conduct a Phase 2 study of VK2809 in patients with hypercholesterolemia and fatty liver disease.

17 Nov 2015

$HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery$

HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery

Researchers at Hospital for Special Surgery have launched a study to determine if a novel implant allowing for less invasive surgery for a broken wrist leads to a quicker recovery, less post-operative pain and fewer complications compared to conventional surgical treatment.

17 Nov 2015

Nearly 50% of Medicaid patients infected with hepatitis C denied coverage for life-saving antiviral drugs

Nearly 50 percent of Medicaid patients infected with chronic hepatitis C whose doctors had prescribed newer, life-saving antiviral drugs were denied coverage to the therapies because they weren't considered "a medical necessity" or because the patients tested positive for alcohol/drugs, among other reasons, according to new Penn Medicine research.

17 Nov 2015

Research shows how scientists altered stem cells, triggered bone growth

Imagine you have a bone fracture or a hip replacement, and you need bone to form, but you heal slowly - a common fact of life for older people. Instead of forming bone, you could form fat. Researchers at the University of North Carolina School of Medicine may have found a way to tip the scale in favor of bone formation. They used cytochalasin D, a naturally occurring substance found in mold, as a proxy to alter gene expression in the nuclei of mesenchymal stem cells to force them to become osteoblasts (bone cells).

17 Nov 2015

CRI scientists identify emergency blood-formation system inside the body

Scientists at the Children's Medical Center Research Institute at UT Southwestern have determined how the body responds during times of emergency when it needs more blood cells. In a study published in Nature, researchers report that when tissue damage occurs, in times of excessive bleeding, or during pregnancy, a secondary, emergency blood-formation system is activated in the spleen.

17 Nov 2015

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

University of Cincinnati researchers have discovered the negative impact a high fat diet has on red blood cells and how these cells, in turn, promote the development of cardiovascular disease.

17 Nov 2015

Bone News and Research

New drug screening method may predict treatment options for patients with multiple myeloma

Ninlaro (ixazomib) approved to treat people with multiple myeloma

NICE recommends Xofigo (radium-223 dichloride) for patients with advanced prostate cancer

New type of drug may help bones heal faster, better

MCG researchers explore how neurofibromatosis puts young patients at risk for cardiovascular disease

Lilly, Merck expand oncology clinical trial collaboration

INP achieves 80% survival rate in acute lymphoblastic leukemia patients

Role of genetic predisposition in pediatric cancer patients

New study finds link between obesity and surgery risk in orthopaedic trauma patients

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Exercise, healthy lifestyle habits may cut prostate cancer risk by up to 68%

Matthew Teeter recognized with 2015 John Charles Polanyi Prize for research in joint replacement

Bone protein can inhibit prostate cancer metastasis to bone

USC discoveries propose promising method to eliminate pain associated with tooth decay

Viking submits IND application to FDA to conduct VK2809 Phase 2 study in patients with LDL-C and fatty liver disease

HSS researchers study outcomes of novel implant in patients undergoing wrist fracture surgery

Nearly 50% of Medicaid patients infected with hepatitis C denied coverage for life-saving antiviral drugs

Research shows how scientists altered stem cells, triggered bone growth

CRI scientists identify emergency blood-formation system inside the body

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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