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Researchers identify a new treatment strategy for neuroblastoma

Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer.

16 Jun 2025

Exercise targets specific brain cells to protect against Alzheimer’s

Using advanced single-nuclei RNA sequencing (snRNA-seq) and a widely used preclinical model for Alzheimer's disease, researchers from Mass General Brigham and collaborators at SUNY Upstate Medical University have identified specific brain cell types that responded most to exercise.

12 Jun 2025

Tufts researchers develop dental implant that mimics real tooth function

Each year, millions of people in the U.S. get dental implants as a long-term, natural-looking fix for missing teeth. But traditional implants don't fully mimic real teeth.

11 Jun 2025

New 3D model reveals hidden role of stem cells in sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

11 Jun 2025

Smelling food triggers fullness through newly found brain pathway

No more hunger after cooking? A newly identified network of nerve cells is responsible, a research group at the Max Planck Institute for Metabolism Research has discovered in mice.

11 Jun 2025

Protein ELAV identified as key regulator of circular RNAs in the brain

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA strands, it forms a closed loop.

10 Jun 2025

Study links reelin to cocaine-induced brain and behavior changes

Cocaine, a drug of abuse, activates just a portion - 10 to 20 percent - of the neurons in the brain's nucleus accumbens, a critical region linked to motivation and addiction.

9 Jun 2025

Brain state-driven neural stimulation improves cognitive flexibility and relieves autistic behaviors

Some autistic traits related to challenges with social interaction, mental flexibility and visual perception could be alleviated through a new, noninvasive therapy.

9 Jun 2025

Scientists identify genetic clues linking air pollution to neurodegeneration

This review highlights how air pollution and occupational inhalation exposures may contribute to neurodegenerative disorders by triggering epigenetic changes. The authors stress the urgent need for advanced research to identify early biomarkers and guide protective health strategies for high-risk populations.

6 Jun 2025

Krakencoder reveals neural connections behind brain function

Using an algorithm they call the Krakencoder, researchers at Weill Cornell Medicine are a step closer to unraveling how the brain's wiring supports the way we think and act.

5 Jun 2025

FDA approves ENCELTO implant to preserve sight in people with macular telangiectasia type 2

For people diagnosed with macular telangiectasia type 2 (MacTel)-a rare and slowly progressing retinal disease-there have been no FDA-approved (or other) treatments to slow or stop vision loss.

4 Jun 2025

Integrating discoveries with translational science to transform Alzheimer's care

At the 12th annual Helen and Robert Appel Alzheimer's Disease Research Institute Symposium, scientists and clinicians shared their latest research which is advancing how Alzheimer's disease is diagnosed and treated.

4 Jun 2025

New molecular mechanism offers hope for causal epilepsy treatments

Epilepsy is primarily treated symptomatically - that is, the majority of the available medications aim to suppress seizures without influencing the underlying causes of the disease.

4 Jun 2025

New mouse model sheds light on smell loss and neural regeneration

A new study suggests that stem cells thought to be dormant may offer clues to why our sense of smell declines or is lost.

3 Jun 2025

Interactive brainwave game shows promise for treating chronic nerve pain

A trial of an interactive game that trains people to alter their brain waves has shown promise as a treatment for nerve pain – offering hope for a new generation of drug-free treatments.

2 Jun 2025

Study identifies diagnostic aid to accurately predict the recurrence of diabetic foot ulcers

NIH-funded project shows that trans-epidermal water loss could indicate if wounds are fully healed.

30 May 2025

New plant-derived therapy shows promise for cancer pain relief

RTX is a non-addictive pain therapy derived from a cactus-like plant.

29 May 2025

Fine-tuned AI tool advances objective evaluation of facial palsy

A "fine-tuned" artificial intelligence (AI) tool shows promise for objective evaluation of patients with facial palsy, reports an experimental study in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons.

29 May 2025

New model creates a realistic picture of how vesicles support synaptic transmission

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles.

28 May 2025

Alzheimer’s blood biomarkers predict faster muscle strength loss in older adults

A large Swedish cohort study found that elevated blood biomarkers associated with Alzheimer’s disease—including p-tau217, p-tau181, neurofilament light chain, and GFAP—predict accelerated muscle strength decline over 12 years in dementia-free older adults. These findings suggest that early identification of Alzheimer’s-related biomarkers could help clinicians intervene sooner to prevent sarcopenia and related adverse outcomes in aging populations.

27 May 2025