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Emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder

In a peer-reviewed article published today in Brain Medicine, a European research team presents a focused review of emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder (OCD).

28 Oct 2025

Uncovering mechanisms of neuronal migration in the adult brain

Researchers have discovered how newly created neurons depend on blood flow in the adult brain to travel from their site of origin to their final location.

28 Oct 2025

Circadian rhythm disruptions may increase the risk of cardiovascular disease

As modern lifestyles increasingly challenge the body's natural circadian rhythm, the American Heart Association is spotlighting the potential health consequences of regular disruptions to our body's internal clock with a new scientific statement published today in its flagship journal Circulation.

28 Oct 2025

Researchers discover a previously unknown genetic cause for microcephaly

Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay.

28 Oct 2025

Scripps Research wins $4 million CIRM grant to develop novel platform for neurodevelopmental disorders

Most people are born with two functioning copies of each gene-one inherited from each parent. In many cases, having just one working copy is enough for the body to function normally.

28 Oct 2025

Exploring the role of the claustrum in psychedelic-induced memory enhancement

Using psychedelics to treat psychiatric diseases has become less controversial as scientists continue to reveal their underlying mechanisms.

27 Oct 2025

Breakthrough study identifies potential treatment for schizophrenia symptoms

Difficulty completing everyday tasks. Failing memory. Unusually poor concentration.

27 Oct 2025

Daily 40Hz audiovisual stimulation may slow cognitive decline in late-onset Alzheimer's patients

A new research paper documents the outcomes of five volunteers who continued to receive 40Hz light and sound stimulation for around two years after participating in an MIT early-stage clinical study of the potential Alzheimer's disease therapy.

27 Oct 2025

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

New research from the Champalimaud Foundation (CF) reveals how missing just one essential amino acid can change gene expression and the brain's sensory systems, prompting animals to seek out protein-rich yeast and gut bacteria that help them restore nutritional balance and survive in times of need.

27 Oct 2025

Scientists uncover excessive maturation and aging in the hippocampus

In a groundbreaking study, researchers at Fujita Health University and the Tokyo Metropolitan Institute of Medical Science have uncovered a previously overlooked form of brain abnormality linked to anxiety: excessive maturation and aging in the hippocampus, a state they term "hyper-maturity."

27 Oct 2025

Unraveling the mystery of motor neuron degeneration in ALS

ALS, also known as Lou Gehrig's disease, is among the most challenging neurological disorders: relentlessly progressive, universally fatal, and without a cure even after more than a century and a half of research.

27 Oct 2025

New mechanism behind potentially fatal type of epilepsy identified

A team led by the UAB Institut de Neurociències (INc-UAB) has for the first time identified the mechanism behind a potentially fatal type of epilepsy, a symptom of mitochondrial diseases.

27 Oct 2025

New insight into TRPM3 heat sensor reveals how the body detects temperature

The ability to sense heat protects the body from burns and injury. But how the body actually feels temperature has remained an elusive mystery.

24 Oct 2025

Les Turner Symposium on ALS brings researchers and clinicians to discuss new research findings

The 15th annual Les Turner Symposium on ALS will be held on Monday, Nov. 3, 2025 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will gather leading ALS researchers and clinicians to discuss the latest research and perspectives on the disease.

23 Oct 2025

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

23 Oct 2025

Hunger and hormones drive aggression in mice

Researchers at the Francis Crick Institute have found that hunger can make virgin female mice aggressive towards pups, but only in certain hormonal states.

22 Oct 2025

New computer model lets researchers simulate how brain circuits make decisions

Every day, your brain makes thousands of decisions under uncertainty. Most of the time, you guess right. When you don't, you learn. But when the brain's ability to judge context or assign meaning falters, thoughts and behavior can go astray.

22 Oct 2025

Understanding the neural mechanisms behind food choices

Feeding in mammals is controlled by a complex neural system. Although several key neural pathways related to total calorie intake have been extensively studied, it is still unclear how food choices are regulated and how they influence overall feeding behavior.

22 Oct 2025

Exercise can mitigate depression-like behaviors induced by high-fat, high-sugar diets

Researchers led by Professor Yvonne Nolan at University College Cork have identified specific metabolic pathways through which exercise counteracts the negative behavioral effects of consuming a Western-style cafeteria diet.

21 Oct 2025

Women with isolated REM sleep behavior disorder show lesser brain atrophy than men

A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson's disease show significantly less brain atrophy—decreased cortical thickness in the brain—than men, despite similar clinical severity.

21 Oct 2025