Next generation sequencing NGS News and Research

RSS

Counsyl unveils significant enhancements to expanded carrier screening panel

Counsyl, a DNA testing and genetic counseling company, today unveiled significant enhancements to its flagship expanded carrier screening product, Counsyl Foresight Carrier Screen, which uses next-generation sequencing technology to assess whether couples are at-risk for passing down serious genetic conditions to their children.

25 Jul 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

Researchers find increased bacterial populations in Alzheimer's brains

Researchers in the UK have used DNA sequencing to examine bacteria in post-mortem brains from patients with Alzheimer's disease.

17 Jul 2017

Targeting immune cells could lead to new treatments for pulmonary fibrosis

Northwestern Medicine scientists have demonstrated that a unique population of immune cells plays a key role in the development of pulmonary fibrosis, and showed that targeting such cells could lead to new treatments for the disease.

13 Jul 2017

Study shows potential of whole genome sequencing and AI to help clinicians scale precision oncology

In a study published today in the July 11, 2017 issue of Neurology Genetics, an official journal of the American Academy of Neurology, researchers at the New York Genome Center, The Rockefeller University and other NYGC member institutions, and IBM have illustrated the potential of IBM Watson for Genomics to analyze complex genomic data from state-of-the-art DNA sequencing of whole genomes.

11 Jul 2017

Scientists find single protein that controls genes essential for spermatogenesis

Scientists have found a single protein--Ptbp2--controls a network of over 200 genes central to how developing sperm move and communicate. The protein works by regulating how RNA is processed during each stage of sperm development.

10 Jul 2017

Timing of mutations can have effect on health and disease

A single genetic mutation can lead to completely different diseases, depending on the time and location at which the mutation occurs.

30 Jun 2017

Beta blockers reverse potentially detrimental genetic changes linked to heart disease

Beta blockers are commonly used world-wide to treat a variety of cardiovascular conditions, such as arrhythmias and heart failure.

30 Jun 2017

Researchers suggest new strategy to identify germline mutations in men with prostate cancer

Scientists have had limited success at identifying specific inherited genes associated with prostate cancer, despite the fact that it is one of the most common non-skin cancers among men.

29 Jun 2017

New TSRI study could have implications for development of flu vaccines, drug therapies

Scientists at The Scripps Research Institute have shown that for the virus that causes the flu, two wrongs can sometimes make a right.

15 Jun 2017

New mutation in MUC1 gene could be valuable biomarker for diagnosing kidney disease

Medullary cystic kidney disease type 1 (MCKD1) is a rare genetic kidney disease. Despite this, because it is an autosomal dominant disease, once the mutation is in a family, many family members are affected. Current diagnostic methods discover the disease late in its development.

14 Jun 2017

Roche to showcase new solutions for lab innovation at EuroMedLab

Roche announced today that it will be showcasing new solutions for lab innovation and leadership at the 22nd IFCC–EFLM European Congress of Clinical Chemistry and Laboratory Medicines in Athens, Greece, 11–15 June.

From Roche Sequencing and Life Science 13 Jun 2017

New targeted oral therapy results in durable responses across many kinds of cancer

Scientists may have developed the first targeted, oral, tumor-type agnostic therapy - a cancer medicine that works comparably well across many kinds of cancer, regardless of patient age. In clinical trials of adults and children with 17 different types of advanced cancer, larotrectinib treatment resulted in responses in 76% of patients.

5 Jun 2017

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

A new analysis finds that nearly three-quarters of 500 patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor's genetic landscape.

2 Jun 2017

ATCC and One Codex form partnership to address microbiome research needs

ATCC, a global leader in biological materials development, management and standards, and One Codex, a leading microbial genomics and metagenomics platform, today announced the formation of a partnership to address microbiome research needs.

2 Jun 2017

IDT and Illumina collaborate to provide improved solutions for next generation sequencing market

Integrated DNA Technologies today announced a broad partnership with Illumina, Inc. to provide improved library preparation multiplexing and target enrichment solutions for the next generation sequencing market.

31 May 2017

Dragon Master Foundation to fund DIPG trial that will make patient data available live in the cloud

Dragon Master Foundation has announced plans to provide $300,000 in funding for the first clinical trial that will make patient data available live in the cloud while the trial is underway.

27 May 2017

OGT makes several advances in hybridization-based targeted sequencing

Oxford Gene Technology, The Molecular Genetics Company, has made several advances in hybridisation-based target enrichment protocols that now enable researchers to prepare samples for sequencing in just one day.

26 May 2017

Researchers identify genetic mutations that predict better prognosis for neuroblastoma patients

The annual mortality rate in childhood cancer of the sympathetic nervous system, or neuroblastoma, is 10 per million between the ages of 0 and 4. The collaborative work between Basque and Valencian researchers has served to identify some genetic mutations that will help to improve the treatment of this disease.

19 May 2017

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Invivoscribe® Technologies Inc., a global company with more than 20 years of experience providing clonality and biomarker test solutions for the fields of oncology, personalized molecular diagnostics® and personalized molecular medicine®, today announces the premarket approval of LeukoStrat® CDx FLT3 Mutation Assay.

3 May 2017