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FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted accelerated approval for Darzalex (daratumumab) to treat patients with multiple myeloma who have received at least three prior treatments. Darzalex is the first monoclonal antibody approved for treating multiple myeloma.

17 Nov 2015

New study refutes increased cancer risk for patients undergoing spinal fusion surgery with rhBMP

A new study may alleviate concerns regarding increased cancer risk for patients undergoing spinal fusion surgery with recombinant human bone morphogenetic protein (rhBMP). The study appears in November 15 issue of Spine, published by Wolters Kluwer.

13 Nov 2015

Older populations in rural areas face special health care challenges

A new study of adults ages 85 or older has found that rural residents have significantly higher levels of chronic disease, take more medications, and die several years earlier than their urban counterparts.

13 Nov 2015

HEAL Project aims to regenerate human knees and limbs within 15 years

On Veteran's Day the University of Connecticut announced the launch of its new grand research challenge: regeneration of a human knee within 7 years, and an entire limb within 15 years.

12 Nov 2015

Loyola and Notre Dame researchers report promising new approaches to treating cancer

Promising new approaches to treating cancer were reported during a recent meeting of researchers from Loyola University Chicago and the University of Notre Dame.

12 Nov 2015

Child care centers play pivotal role in physical activity levels of preschoolers

A new study published in the American Journal of Preventive Medicine finds child care centers play a pivotal role when it comes to the physical activity levels of preschoolers. Yet few children get to experience outdoor recess time as it is scheduled. Only 3 in 10 children had at least 60 minutes of a full child-care day outdoors for recess, as is recommended by guidelines.

12 Nov 2015

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

New Haven Pharmaceuticals, Inc. today announced new study data that shows the company's FDA-approved drug DURLAZA delivers sustained antiplatelet control for a full 24-hour period in high-risk patients.

10 Nov 2015

Agios announces data from dose-escalation phase 1 study of AG-120 in patients with IDH1 mutant positive advanced solid tumors

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and rare genetic metabolic disorders, today announced the first data from the dose-escalation portion of the ongoing Phase 1 study evaluating single agent AG-120, a first-in-class, oral, selective, potent inhibitor of mutant isocitrate dehydrogenase-1 (IDH1), in advanced solid tumors. The data are being presented today at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston. AG-120 is being developed in collaboration with Celgene.

9 Nov 2015

Researchers develop novel technology for chronic arthritis

Joint inflammation (arthritis) is a common problem in medical practice and can be due to a variety of causes. Many types of inflammatory disorders affecting the joints belong to the diverse group of rheumatic diseases.

6 Nov 2015

Novel genetic therapy treats ‘incurable’ leukaemia

A new treatment that involves editing DNA has been used for the first time at Great Ormond Street Hospital to successfully treat drug-resistant leukaemia.

6 Nov 2015

Boxing more dangerous than mixed martial arts, shows study

Mixed martial arts has a reputation for being one of the most brutal and bloody of all contact sports, but the reality is boxing poses a greater risk of serious injury, according to new research from the University of Alberta.

6 Nov 2015

Bone density related to duration of lactation

Maternal bone density decreases after childbirth, but only among women who lactate for at least four months. The lactation period is unrelated to vitamin D status. A PhD thesis at Sahlgrenska Academy has explored the issue.

6 Nov 2015

Genvoya approved as complete regimen for HIV treatment

The U.S. Food and Drug Administration today approved Genvoya (a fixed-dose combination tablet containing elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide) as a complete regimen for the treatment of HIV-1 infection in adults and pediatric patients 12 years of age and older.

6 Nov 2015

Multicenter trial compares popular treatments for menopause-related vaginal symptoms

Hot flashes. Night sweats. These are the most common - or at least the most commonly talked about - symptoms of menopause. But one reality of The Change for many women is less discussed yet no less important: problems with vaginal health and sexual function.

6 Nov 2015

Doctoral thesis explores issues related to dental Implants

Almost 8 percent of patients experience loss of at least one implant within ten years. Even more develop peri-implantitis. Patients with periodontitis run a greater risk of both implant loss and peri-implantitis. A doctoral thesis at Sahlgrenska Academy has explored the various issues.

5 Nov 2015

Janssen doses first patient in daratumumab clinical trial using Halozyme's ENHANZE technology

Halozyme Therapeutics, Inc. today announced that Janssen Biotech, Inc. has dosed the first patient in a clinical trial evaluating subcutaneous (SC) delivery of daratumumab with Halozyme's proprietary ENHANZE technology in multiple myeloma.

5 Nov 2015

Estrogen-like drug may not be beneficial to women with Alzheimer's dementia

An estrogen-like drug, raloxifene, has no demonstrated benefit on memory and thinking skills for women with dementia due to Alzheimer's disease, according to a study published in the November 4, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

5 Nov 2015

Doing exercise during puberty can improve bone health in adulthood, Spanish study confirms

Osteoporosis is a serious health issue that mainly affects postmenopausal women. Now, a Spanish study has confirmed that doing exercise during puberty can improve bone health in adulthood. In this scope, sports such as football, handball and basketball are better than others such as swimming.

5 Nov 2015

Cerapedics' i-FACTOR Peptide Enhanced Bone Graft gets FDA approval for use in cervical spine surgery

Cerapedics, a privately-held orthobiologics company, announced today the U.S. Food and Drug Administration (FDA) has approved the company’s Premarket Approval (PMA) application for i-FACTOR™ Peptide Enhanced Bone Graft for use in anterior cervical discectomy and fusion (ACDF) procedures in patients with degenerative cervical disc disease. i-FACTOR bone graft is the first bone graft to be approved for use in the cervical spine and only the second PMA-approved bone graft in the spine.

4 Nov 2015

New DentaPlas coated implants help prevent infections caused by bacteria

One million dental implants are inserted every year in Germany, and often they need to be replaced due to issues such as tissue infections caused by bacteria. In the future, these infections will be prevented thanks to a new plasma implant coating that kills pathogens using silver ions.

4 Nov 2015

Bone News and Research

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

New study refutes increased cancer risk for patients undergoing spinal fusion surgery with rhBMP

Older populations in rural areas face special health care challenges

HEAL Project aims to regenerate human knees and limbs within 15 years

Loyola and Notre Dame researchers report promising new approaches to treating cancer

Child care centers play pivotal role in physical activity levels of preschoolers

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

Agios announces data from dose-escalation phase 1 study of AG-120 in patients with IDH1 mutant positive advanced solid tumors

Researchers develop novel technology for chronic arthritis

Novel genetic therapy treats ‘incurable’ leukaemia

Boxing more dangerous than mixed martial arts, shows study

Bone density related to duration of lactation

Genvoya approved as complete regimen for HIV treatment

Multicenter trial compares popular treatments for menopause-related vaginal symptoms

Doctoral thesis explores issues related to dental Implants

Janssen doses first patient in daratumumab clinical trial using Halozyme's ENHANZE technology

Estrogen-like drug may not be beneficial to women with Alzheimer's dementia

Doing exercise during puberty can improve bone health in adulthood, Spanish study confirms

Cerapedics' i-FACTOR Peptide Enhanced Bone Graft gets FDA approval for use in cervical spine surgery

New DentaPlas coated implants help prevent infections caused by bacteria

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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