Genes News and Research

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Hereditary genes correlate with a greater probability of developing cancer mutations, finds study

A study of 11,000 cancer patients reveals 42 hereditary genes which predispose individuals to a higher number of mutations that correlate with a greater probability of developing cancer.

5 Jul 2022

Roundworms shed light on vision loss in a rare human genetic disorder

In this interview, News-Medical speaks to Xinxing Zhang, a postdoctoral research fellow at the University of Michigan, about his research investigating vision loss in Bardet-Biedl syndrome.

4 Jul 2022

Elevated cerebrospinal fluid biomarkers of neuroinflammation in NeuroCOVID patients

A new research paper studied several biomarkers associated with neuronal injury, neuroinflammation, and neurodegeneration in NeuroCOVID adults who experienced a CNS syndrome during acute SARS-CoV-2 infection.

4 Jul 2022

Brain immune response to SARS-CoV-2 infection

In a recently published article in the journal Current Opinion in Neurobiology, scientists at Washington University School of Medicine, St. Louis have described how immunological alterations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may impact brain activities and induce acute and post-acute neurological symptoms in coronavirus disease 2019 (COVID-19) patients.

3 Jul 2022

Scientists demonstrate key role of an enzyme in facilitating ovarian cancer metastasis in the omentum

In their recent publication in Cell Reports, a team of scientists, led by Xiling Shen, Ph.D., Chief Scientific Officer at the Terasaki Institute for Biomedical Innovation (TIBI), has demonstrated the pivotal role of an enzyme, glucose-6-phosphate dehydrogenase (G6PD), in facilitating ovarian cancer (OC) growth and metastasis in the omentum, a curtain of fatty tissue found in the abdominal cavity.

2 Jul 2022

Scientists use transcriptomics to explore the ancient origins of placenta

The fossil record tells us about ancient life through the preserved remains of body parts like bones, teeth and turtle shells.

1 Jul 2022

Transcriptomic data reveals the evolutionary relationships of two groups of ancient invertebrates

Kamptozoa and Bryozoa are two phyla of small aquatic invertebrates. They are related to snails and clams (collectively called mollusks), bristleworms, earthworms, and leeches (collectively called annelids), and ribbon worms (nemertea).

1 Jul 2022

New, safer CRISPR approach may help correct genetic defects in the future

Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their families, although the safety of these new methods is still of significant concern.

1 Jul 2022

Chemical-based sequencing method to efficiently study DNA methylation

One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off.

1 Jul 2022

A convergent mechanism for two top-ranking risk genes may be responsible for ASD/ID

University at Buffalo scientists have discovered a convergent mechanism that may be responsible for how two top-ranked genetic risk factors for autism spectrum disorder/intellectual disability (ASD/ID) lead to these neurodevelopmental disorders.

1 Jul 2022

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore together with collaborators in Europe and South Korea, used single-cell techniques to uncover a central dichotomy for colorectal cancer cells, leading to a proposed update of the classification system for the disease.

1 Jul 2022

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Researchers explored the molecular basis for increased immunity against heterologous SARS-CoV-2 strains after repeated antigen exposures.

1 Jul 2022

Combining AI and Zebrafish to Accelerate Drug Discovery

As part of our SLAS Europe 2022 coverage, we speak to Dr. Javier Terriente, Co-founder and Chief of Drug Development at ZeClinics, about how zebrafish could be the future for discovering new therapeutics.

From Society for Laboratory Automation and Screening (SLAS) 1 Jul 2022

HIV accelerates epigenetic aging soon after initial HIV infection

HIV has an "early and substantial" impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to a study by UCLA researchers and colleagues.

1 Jul 2022

Researchers discover new family of sensing genes in enteric bacteria using AI

Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence.

30 Jun 2022

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Bioaerosols, or airborne biological particles containing viruses, fungal spores, bacteria, and pollen, play a key role in public health. Antibiotic resistance (AR), caused by antibiotic resistance genes (ARGs), could potentially cause global public health crises owing to horizontal gene transfer between same or similar bacterial bioaerosols.

30 Jun 2022

Key protein α-synuclein linked to inflammation and Parkinson's disease

Currently, there are no disease modifying therapies for Parkinson's disease that can change the progression of the disease. An international team of scientists led by faculty at the University of Colorado Anschutz Medical Campus is hoping to change that.

30 Jun 2022

Study uncovers new gene that increases Alzheimer's disease risk in women

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S. Scientists have discovered some genetic variants that increase the risk for developing Alzheimer's; the most well-known of these for people over the age of 65 is the APOE ε4 allele.

30 Jun 2022

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Researchers used isothermal amplification with CRISPR-Cas12a to detect SARS-CoV-2.

30 Jun 2022

New approaches for getting and maximizing usable DNA from decades-old pickled specimens

Two levels underground, Chicago's Field Museum has a secret bunker. The sub-basement Collections Resource Center houses millions of biological specimens for scientists around the world to use in their research, including countless bottles and jars containing pickled fish, lizards, and snakes, arranged like a library.

30 Jun 2022

Genes News and Research

Hereditary genes correlate with a greater probability of developing cancer mutations, finds study

Roundworms shed light on vision loss in a rare human genetic disorder

Elevated cerebrospinal fluid biomarkers of neuroinflammation in NeuroCOVID patients

Brain immune response to SARS-CoV-2 infection

Scientists demonstrate key role of an enzyme in facilitating ovarian cancer metastasis in the omentum

Scientists use transcriptomics to explore the ancient origins of placenta

Transcriptomic data reveals the evolutionary relationships of two groups of ancient invertebrates

New, safer CRISPR approach may help correct genetic defects in the future

Chemical-based sequencing method to efficiently study DNA methylation

A convergent mechanism for two top-ranking risk genes may be responsible for ASD/ID

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Combining AI and Zebrafish to Accelerate Drug Discovery

HIV accelerates epigenetic aging soon after initial HIV infection

Researchers discover new family of sensing genes in enteric bacteria using AI

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Key protein α-synuclein linked to inflammation and Parkinson's disease

Study uncovers new gene that increases Alzheimer's disease risk in women

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

New approaches for getting and maximizing usable DNA from decades-old pickled specimens

eBook: Using iPSCs models for human disease research and drug discovery eBook

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