Research News and Research

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Novel immunotherapy combination can be highly effective for treating lung cancer

McMaster University researchers have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer.

27 Jan 2021

Two-drug combination approach could be effective against bone cancer

An innovative approach to treating bone tumors - starving cancer cells of the energy they need to grow - could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. Louis.

27 Jan 2021

Looming eviction crisis may put Californians at increased risk for unmet medical needs

Research published in the peer-reviewed Journal of General Internal Medicine found that Californians who had moved due to unaffordable housing are significantly more likely to report unmet medical needs compared to people with non-cost-related moves.

27 Jan 2021

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Now, in new research posted to the preprint server bioRxiv*, scientists use an experimental structure of the Spike RBD domain co-crystallized with part of the ACE2 receptor and several in silico methods to analyze the possible impacts of three amino acid replacements (Spike K417N, E484K, N501Y) concerning ACE2 binding.

27 Jan 2021

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Cell phone data that is routinely collected by telecommunications providers can reveal changes of behavior in people who are diagnosed with a flu-like illness, while also protecting their anonymity, a new study finds.

26 Jan 2021

Iron-carrying extracellular vesicles promote viral-bacterial co-infection

The mechanism by which acute viral respiratory infections promote secondary bacterial growth and infection in the airways depends on iron-carrying extracellular sacs secreted by the cells lining the host's airways, report researchers from the University of Pittsburgh School of Medicine in a paper published today in Cell Reports.

26 Jan 2021

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

26 Jan 2021

Initial stages of breast cancer could be detected more accurately with new proteomics-based technology

Breast cancer, even at its initial stages, could be detected earlier and more accurately than current techniques using blood samples and a unique proteomics-based technology, according to findings of a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

26 Jan 2021

Study shows why children of obese mothers have propensity to develop metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop metabolic disease during their lifetime, as suggested by previous research.

26 Jan 2021

Remdesivir disrupts SARS-CoV-2 more effectively than other similar drugs

In the treatment of SARS-CoV-2, the virus that causes COVID-19, antiviral drug remdesivir has emerged as a promising candidate.

26 Jan 2021

Children determine emotion by what they hear, rather than what they see

Children determine emotion by what they hear, rather than what they see, according to new research. The first-of-its-kind study, by Durham University's Department of Psychology, looked at how children pick up on the emotions of a situation.

26 Jan 2021

Novel platform uses modified virus to combat pancreatic cancer

Researchers from Queen Mary University of London and Zhengzhou University have developed a powerful therapeutic platform that uses a modified virus for the treatment of pancreatic cancer.

26 Jan 2021

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Blood draws are no fun. They hurt. Veins can burst, or even roll - like they're trying to avoid the needle too, Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and sepsis.

26 Jan 2021

Drugged driving is outpacing drunk driving, shows study

A recent study of drugged driving, by a team of University of Cincinnati researchers, shows that a sizable percentage of individuals reported the use of marijuana and other illicit drugs while operating behind the wheel.

26 Jan 2021

Study shows how gut bacteria can dull the efficacy of radiotherapy

A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received by about half of all cancer patients.

26 Jan 2021

Sodium fluorescein may improve the safety and outcomes of vestibular schwannoma surgery

Removing a vestibular schwannoma - a slow-growing, benign tumor that develops in the nerves connecting the inner ear to the brain - is a delicate procedure. Surgeons must differentiate the tumor from nearby nerves, arteries, and other intracranial structures.

26 Jan 2021

Genetic interactions may shed light on NGLY1 deficiency

In 2012, four-year-old Bertrand Might became the first-ever patient diagnosed with a rare genetic disorder called N-glycanase (NGLY1) deficiency. The discovery of this condition and Bertrand's diagnosis allowed doctors to look for other children with the same genetic defect. Since then, more than 60 additional patients have been found.

26 Jan 2021

Research News and Research

Novel immunotherapy combination can be highly effective for treating lung cancer

Two-drug combination approach could be effective against bone cancer

Looming eviction crisis may put Californians at increased risk for unmet medical needs

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Iron-carrying extracellular vesicles promote viral-bacterial co-infection

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Initial stages of breast cancer could be detected more accurately with new proteomics-based technology

Study shows why children of obese mothers have propensity to develop metabolic diseases

Remdesivir disrupts SARS-CoV-2 more effectively than other similar drugs

Children determine emotion by what they hear, rather than what they see

Novel platform uses modified virus to combat pancreatic cancer

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Drugged driving is outpacing drunk driving, shows study

Study shows how gut bacteria can dull the efficacy of radiotherapy

Sodium fluorescein may improve the safety and outcomes of vestibular schwannoma surgery

Genetic interactions may shed light on NGLY1 deficiency

Study uses computational framework to identify tamoxifen resistance markers in ER+ breast cancer

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Anti-emetic drug offers a promising approach to treat chronic myeloid leukemia

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