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Single enzyme doing the work of a trio could offer precise way to treat diseases

Researchers identified a single enzyme doing the work of a trio thought necessary to control a common cellular signaling process being pursued as a therapeutic target.

24 May 2016

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Patients with ulcerative colitis (UC) may improve their symptoms with a transplantation of healthy stool from donors, according to Australian researchers. The findings were presented by Dr Sudarchan Paramsothy MD, a gastroenterologist from the University of New South Wales, Australia at the Digestive Disease Week conference in San Diego, California between the 21st to 24th May.

24 May 2016

Antimicrobial agent triclosan can rapidly disrupt gut bacterial communities

A new study suggests that triclosan, an antimicrobial and antifungal agent found in many consumer products ranging from hand soaps to toys and even toothpaste, can rapidly disrupt bacterial communities found in the gut.

24 May 2016

Scientists create computational network model to understand human physiology and disease

Scientists at UMass Medical School have created a computational network model that will enable the unraveling of the mechanisms by which different macro- and micronutrients contribute to the physiology of the nematode C. elegans, which is a primary model for understanding human physiology and disease.

23 May 2016

Harvard researchers create new, simplified platform for antibiotic discovery

Harvard researchers have created a new, greatly simplified, platform for antibiotic discovery that may go a long way to solving the crisis of antibiotic resistance.

23 May 2016

Specific monocyte immune cells serve as link between gut bacteria and the brain

A special kind of immune cell serves as an intermediary between gut bacteria and the brain. Dr. Susanne Wolf of the Max Delbruck Center for Molecular Medicine in the Helmholtz Association discovered this in tests on mice and published her findings in the journal Cell Reports.

20 May 2016

New frozen faecal bank increases chances of curing a chronic health condition

A new frozen faecal bank that could save hundreds of lives and dramatically improve the quality of life of many more has been established at a Portsmouth hospital.

20 May 2016

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica.

19 May 2016

Crtc switch activated during fasting helps halt spread of intestinal bacteria into bloodstream

A molecular pathway that is activated in the brain during fasting helps halt the spread of intestinal bacteria into the bloodstream, according to a new study by a team of researchers at the Salk Institute.

18 May 2016

Food components can have significant influence on immune system

An international team of researchers under the leadership of the LIMES Institute and the excellence cluster ImmunoSensation of the University of Bonn unraveled a new regulatory mechanism how food components and environmental factors influence the immune system.

18 May 2016

Scientists uncover whole new way of treating antibiotic-resistant superbugs

Australian scientists may have found a way to stop deadly bacteria from infecting patients. The discovery could lead to a whole new way of treating antibiotic-resistant "superbugs". The researchers have uncovered what may be an Achilles heel on the bacteria cell membrane that could act as a potential novel drug target.

17 May 2016

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

The hygiene hypothesis refers to the idea that decreased exposure to certain infectious agents (because of better hygiene) is the reason why we have seen an increase in inflammatory diseases in the developed world.

17 May 2016

New molecule has potential to prolong life of cystic fibrosis patients

Scientists at Queen's University Belfast have discovered a new molecule which has the potential to prolong the life of individuals with cystic fibrosis (CF).

12 May 2016

Simple, cheap chemical sensors may detect developing cancers in future

Many cancers could be successfully treated if the patient consulted the doctor sufficiently early. But how can a developing cancer be detected if it doesn't give rise to any symptoms? In the near future, suitably early diagnosis could be provided by simple and cheap chemical sensors - thanks to special recognizing polymer films developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw.

12 May 2016

High-throughput screening can help detect multiple compounds with potent antimicrobial activity

A new study in which researchers rapidly screened more than 11,000 bioactive molecules for activity against an antibiotic-resistant strain of Klebsiella pneumoniae bacteria identified multiple compounds with potent antimicrobial activity.

12 May 2016

Scientists identify new hots pots of antibiotic resistance

Antibiotic-resistant bacteria most often are associated with hospitals and other health-care settings, but a new study indicates that chicken coops and sewage treatment plants also are hot spots of antibiotic resistance.

12 May 2016

Human gut model HuMiX represents actual conditions, processes that occur within intestines

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria.

11 May 2016

Innovative technology in NICU can predict risk of major infections in premature or critically ill babies

A new technology in the Neonatal Intensive Care Unit at UC San Diego Health is able to predict the risk of life-threatening infections up to 24 hours before they appear in severely premature or critically ill infants. Infection is the leading cause of death in this fragile patient population.

11 May 2016

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics.

10 May 2016

MGH researchers develop device to rapidly diagnose health-care-associated infections

A team of Massachusetts General Hospital investigators has developed a device with the potential of shortening the time required to rapidly diagnose pathogens responsible for health-care-associated infections from a couple of days to a matter of hours.

10 May 2016

Bacterial News and Research

Single enzyme doing the work of a trio could offer precise way to treat diseases

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Antimicrobial agent triclosan can rapidly disrupt gut bacterial communities

Scientists create computational network model to understand human physiology and disease

Harvard researchers create new, simplified platform for antibiotic discovery

Specific monocyte immune cells serve as link between gut bacteria and the brain

New frozen faecal bank increases chances of curing a chronic health condition

Natural product darwinolide may help combat fatal MRSA infection

Crtc switch activated during fasting helps halt spread of intestinal bacteria into bloodstream

Food components can have significant influence on immune system

Scientists uncover whole new way of treating antibiotic-resistant superbugs

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

New molecule has potential to prolong life of cystic fibrosis patients

Simple, cheap chemical sensors may detect developing cancers in future

High-throughput screening can help detect multiple compounds with potent antimicrobial activity

Scientists identify new hots pots of antibiotic resistance

Human gut model HuMiX represents actual conditions, processes that occur within intestines

Innovative technology in NICU can predict risk of major infections in premature or critically ill babies

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

MGH researchers develop device to rapidly diagnose health-care-associated infections

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