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Two studies show potential for newborn genetic screening

Two studies published today in the American Journal of Human Genetics show the potential for genomic screening in newborns to address high rates of infant hospitalization and mortality in the United States.

9 Dec 2024

Engineered immune cells could transform treatment for autoimmune diseases

Immune cells that are designed to soothe could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions.

9 Dec 2024

Developing climate-resilient crops is essential for global food security

Increasing heat, droughts, floods, and salinization caused by climate change are lowering the amount of edible food produced by our staple crops.

9 Dec 2024

Breakthrough discovery in BK polyomavirus replication offers hope for kidney transplant protection

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV.

6 Dec 2024

Study reveals how DNA folding drives gene activity bursts

Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity.

6 Dec 2024

Bacterial toxin may fuel colorectal cancer metastasis

A toxin in the bacteria that's one of the most common causes of foodborne illness accelerates the spread of colorectal tumors to other parts of the body, a study led by UF Health Cancer Center researchers and international collaborators has found.

6 Dec 2024

$1.5 million grant supports alternatives to opioids initiative at University Hospitals

A grant of nearly $1.5 million from the Department of Health and Human Services through its Substance Abuse and Mental Health Services Administration (SAMHSA) will enable University Hospitals Cleveland Medical Center to develop and implement an Alternatives to Opioids (ALTO) program within its Emergency Department (ED).

6 Dec 2024

New insights into the mechanisms of "Niemann-Pick type C" in children

In the journal "Science Translational Medicine", scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.

6 Dec 2024

Dual-antibody therapy shows promise in treating metastatic colorectal cancer

Metastatic colorectal cancer (mCRC) remains a daunting challenge, especially after first-line treatments fail.

6 Dec 2024

New technology guides immune cells to fight brain cancer and multiple sclerosis

Researchers have found a way to program immune cells to attack glioblastoma and treat the inflammation of multiple sclerosis in mice.

6 Dec 2024

New compound HPH-15 offers promising alternative to diabetes medications

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.

6 Dec 2024

MRI-based imaging technique predicts the response of ovarian cancer to treatment

An MRI-based imaging technique developed at the University of Cambridge predicts the response of ovarian cancer tumors to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.

6 Dec 2024

Mapping blood system changes offers new hope for leukemia treatments

Researchers at University of California San Diego School of Medicine and their colleagues have developed the first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime.

6 Dec 2024

Study uncovers mechanism behind nutrient scavenging in pancreatic cancer

Cancer cells are like booming cities without urban planners. They expand quickly, and in doing so, the resulting tumors consume more energy and other resources than they can acquire from nearby blood vessels.

6 Dec 2024

Researchers discover new receptor in pain signaling pathway

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a study published in the Journal of Clinical Investigation.

6 Dec 2024

SigRM offers breakthrough in single-cell epitranscriptomics analysis

Researchers have developed a new tool that will help scientists study how genes are expressed in our cells.

6 Dec 2024

p53 mutations show diverse impact on pancreatic cancer metabolism

A research team at the University of Konstanz, led by toxicologist Ivano Amelio, has demonstrated how differently individual mutations of the tumor suppressor p53 affect pancreatic carcinomas.

6 Dec 2024

New collaborative effort aims to cure ALK-positive lung cancer

Lung cancer is the leading cause of cancer death worldwide, with various subtypes affecting millions of people each year.

6 Dec 2024

Understanding how the skin's neurons process social touch signals

Two types of neurons in the skin may be particularly important for how the brain interprets social contact between people, according to a new study led by Linköping University in Sweden.

6 Dec 2024

Reimagining axons with the pearls-on-a-string model

In a provocative new study, scientists challenge a fundamental tenet in neuroscience about the shape of axons -- the long, thin filaments radiating from nerve cells that transmit electrical signals from cell to cell – and propose a new model for understanding how information is transmitted in the brain.

6 Dec 2024