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New studies on fat cell filling, history of biochemistry, and ketogenic diet

There's more than one type of fat cell. Besides the white fat that stores triglycerides in lipid droplets in preparation for lean times later, mammals also have heat-generating brown fat, which acts more like a radiator than a storage closet.

14 Jun 2018

Extensive lipidomics studies reveal signatures of metabolic health and disease

Scientists from EPFL and the University of Wisconsin-Madison have carried out one of the most extensive lipidomics studies to date, connecting almost 150 different lipid species to their respective genetic regulators, revealing signatures of metabolic health and disease.

13 Jun 2018

Researchers develop biomimetic nanosystem to deliver therapeutic proteins to target tumors

A team of Penn State researchers has developed a biomimetic nanosystem to deliver therapeutic proteins to selectively target cancerous tumors.

13 Jun 2018

Video consultations boost survival rates of liver disease patients, study finds

For patients who live in rural areas, driving to see a specialist in a large city or at a university hospital can be challenging, if not impossible.

12 Jun 2018

New blood test better than having a needle inserted into the eye

People diagnosed with a deadly form of cancer will no longer face the prospect of having a needle inserted into their eye thanks to a new blood test developed by Edith Cowan University researchers.

12 Jun 2018

Scientists pinpoint potential treatment target for pediatric liver cancer

A protein in the cell nucleus already targeted therapeutically for several types of cancer has now been linked to an aggressive form of pediatric liver cancer called hepatoblastoma (HBL), according to a study published in the Nature journal Communications Biology.

11 Jun 2018

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Translate Bio, a clinical-stage messenger RNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced today a multi-year research and development collaboration and exclusive licensing agreement with Sanofi Pasteur, the vaccines global business unit of Sanofi, to develop mRNA vaccines for up to five undisclosed infectious disease pathogens.

11 Jun 2018

Research shows that treating cholestasis in father lowers risk of high blood pressure in son

New research led by Professor Catherine Williamson, School of Life Course Sciences, shows that using drugs to treat male mice with cholestasis reduced the likelihood of male offspring developing high blood pressure.

11 Jun 2018

Changes to the immune system remain even after recovery from HCV infection, shows study

Changes to the immune system remain many years after a hepatitis C infection heals, a new study by researchers at Karolinska Institutet, Sweden, and Hannover Medical School, Germany, shows.

11 Jun 2018

Scientists discover how certain foods can help protect against health issues

The foods we eat play a significant role in our health. Scientists are discovering how eggs, nuts, dairy products, vegetables and even coffee can help protect against health problems.

11 Jun 2018

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

Livestock may play important role in epidemiology of leptospirosis in sub-Saharan Africa

Leptospirosis, which affects more than one million people worldwide each year, is known to be transmitted to humans from a wide range of animals. Now, researchers reporting in PLOS Neglected Tropical Diseases have discovered that more than 7 percent of the cattle and 1 percent of sheep and goats in local slaughterhouses in northern Tanzania are infected with Leptospira bacteria.

8 Jun 2018

Study finds cattle as possible source of human leptospirosis in Africa

The bacterial infection leptospirosis is increasingly recognized as an important cause of fever in Africa. Now, researchers reporting in PLOS Neglected Tropical Diseases have analyzed the major risk factors for contracting leptospirosis and discovered that rice and cattle farming are associated with acute infection.

8 Jun 2018

New analytical method improves diagnosis and monitoring of cancer

Ten times more sensitive than current techniques, the technique allows, from a blood serum sample, to simultaneously detect different biomarkers related to cancer.

8 Jun 2018

Practicing with fake organs helps surgeon to perform complex cancer surgery

Anthony Camnetar remembers the first time he was told that he had von Hippel-Lindau syndrome, a rare genetic disorder.

7 Jun 2018

Study finds high insurance denial rates for life-saving hepatitis C drugs in the U.S.

The number of insurance denials for life-saving hepatitis C drugs among patients with both private and public insurers remains high across the United States, researchers from the Perelman School of Medicine at the University of Pennsylvania reported in a new study published in the journal Open Forum Infectious Diseases.

7 Jun 2018

With the rise of legal weed, drug education moves from ‘don’t’ to ‘delay’

California legalized marijuana in 2016, and this past New Year’s Eve eager customers lined up in the darkness outside medical marijuana dispensaries across the state, ready to start shopping at the stroke of midnight.

7 Jun 2018

Naturally occurring antibody can block inflammation in mice, finds study

Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids, molecules on cell surfaces that get modified by inflammation.

7 Jun 2018

New nuclear medicine method appears to effectively detect neuroendocrine tumors

Researchers have shown that a new nuclear medicine procedure could safely and more effectively detect cancerous gastrointestinal and pancreatic neuroendocrine tumors than current methods.

7 Jun 2018

Overload of zinc in muscles leads to cachexia in cancer patients

It's estimated that nearly one-third of all cancer deaths are caused not by the cancer itself but by cachexia - a debilitating muscle-wasting syndrome that affects an estimated 80 percent of advanced cancer patients. Cachexia is linked to reduced tolerance for cancer therapy, poor quality of life, and accelerated death, but there are no effective treatments and its cause is still largely unknown.

6 Jun 2018