Protein C News and Research

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World's fastest camera can detect fluorescence from single molecules

Researchers at Kyoto University, Okinawa Institute of Science and Technology Graduate University (OIST), and Photron Limited in Japan have developed the world's fastest camera capable of detecting fluorescence from single molecules.

6 Jun 2023

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood pressure) – the leading cause of cardiovascular disease affecting 1.25 billion people worldwide.

6 Jun 2023

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

Therapeutic nanocarriers engineered from adult skin cells can curb inflammation and tissue injury in damaged mouse lungs, new research shows, hinting at the promise of a treatment for lungs severely injured by infection or trauma.

6 Jun 2023

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

Researchers explored the phytochemical contents and health benefits of consuming figs.

6 Jun 2023

Breakthrough: Sequencing functional antibody proteins directly from human blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

Experts investigate the correlation between BORIS mutations and protein expression

A new research paper was published in Oncotarget's Volume 14 on May 26, 2023, entitled, "Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression."

6 Jun 2023

Efficient machine learning pipeline predicts the location of nanoscale interactions

Identifying whether and how a nanoparticle and protein will bind with one another is an important step toward being able to design antibiotics and antivirals on demand, and a computer model developed at the University of Michigan can do it.

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

According to the federal government's National Institute of Neurological Disorders and Stroke, nearly 3 million people worldwide - with almost a third in the United States - are living with multiple sclerosis (MS), a disabling neurological disease in which the body's immune system mistakenly attacks nerves feeding information to the central nervous system (the brain and spinal cord). Although rarely fatal, MS can lead to long-term disabilities, and impair movement, muscle control, vision and cognition.

6 Jun 2023

The universal role of Nsp1: Common mechanisms of translational shutdown by coronaviruses

Researchers investigate Nsp1 from SARS-CoV-2, MERS-CoV, and Bat-Hp-CoV using biophysical, structural, and biochemical assays.

5 Jun 2023

HER2-targeted antibody drug conjugate shows encouraging responses, long-lasting clinical benefit in several tumor types

In a new study of trastuzumab deruxtecan, a HER2-targeted antibody drug conjugate, researchers observed encouraging responses and long-lasting clinical benefit in several tumor types.

5 Jun 2023

CRISPR/Cas9 identifies a gene critical to stony corals' ability to build their skeletons

New work led by Carnegie's Phillip Cleves uses cutting-edge CRISPR/Cas9 genome editing tools to reveal a gene that's critical to stony corals' ability to build their reef architectures.

5 Jun 2023

Research sheds new light on the genetic architecture of bipolar disorder

Bipolar disorder (BD) is a major psychiatric condition that afflicts about 1% of people. Symptoms of BD include sudden onset of depressive mood with loss of interest which alternates with a manic state of hyperactivity.

5 Jun 2023

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Researchers described a novel strategy for controlling severe acute respiratory syndrome coronavirus 2.

5 Jun 2023

Is translocator protein distribution volume elevated in the brain after acute COVID-19 infection with sequelae of depressive and cognitive symptoms?

Researchers discuss the occurrence of neuroinflammation after coronavirus disease 2019.

5 Jun 2023

Research opens door to new, more efficient drug combinations for acute myeloid leukemia

Acute myeloid leukemia (AML) is a very aggressive disease in which cells proliferate abnormally, invading the bone marrow and interfering with normal blood cell production. It is the most common acute leukemia in adults with the worst prognosis.

5 Jun 2023

Testing for dangerous 'zombie' cells could increase the number of donor hearts for transplant

Testing older potential organ donors for dangerous 'zombie' cells could help to increase the number of hearts available for transplant, according to research part-funded by the British Heart Foundation (BHF) and presented at the British Cardiovascular Society conference in Manchester.

4 Jun 2023

SWOG Cancer Research Network clinical trial reveals potential new therapy for Stage 3 or 4 classic Hodgkin lymphoma

A Phase 3 trial has demonstrated that patients with advanced stage (3 or 4) classic Hodgkin lymphoma who underwent initial treatment with nivolumab, a PD-1 checkpoint inhibitor, and AVD chemotherapy (N-AVD) had a significantly lower risk of their cancer getting worse than patients treated with brentuximab vedotin, a monoclonal antibody, and AVD (BV-AVD) a year after starting treatment.

4 Jun 2023

Study shows efficacy and safety of novel FolRα-targeting antibody drug conjugate in recurrent epithelial ovarian cancer

Updated dose expansion data of the phase I STRO-002-GM1 study have been presented today by Ana Oaknin, Principal Investigator of the Vall d'Hebron Institute of Oncology's (VHIO) Gynecological Malignancies Group, on the ground at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO), 2-6 June in Chicago, USA.

4 Jun 2023

Unpacking the nutrient profiles of new-age plant-based foods: Are they truly healthier?

Concerns about the environment, ethics, and health drive the adoption of plant-based diets, but the healthiness of next-generation plant-based alternatives remains uncertain. Research explores the need to optimize nutrient profiles, digestibility, and bioavailability of plant-based foods for enhanced health benefits.

4 Jun 2023

Protein C News and Research

World's fastest camera can detect fluorescence from single molecules

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

Breakthrough: Sequencing functional antibody proteins directly from human blood

Experts investigate the correlation between BORIS mutations and protein expression

Efficient machine learning pipeline predicts the location of nanoscale interactions

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

The universal role of Nsp1: Common mechanisms of translational shutdown by coronaviruses

HER2-targeted antibody drug conjugate shows encouraging responses, long-lasting clinical benefit in several tumor types

CRISPR/Cas9 identifies a gene critical to stony corals' ability to build their skeletons

Research sheds new light on the genetic architecture of bipolar disorder

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Is translocator protein distribution volume elevated in the brain after acute COVID-19 infection with sequelae of depressive and cognitive symptoms?

Research opens door to new, more efficient drug combinations for acute myeloid leukemia

Testing for dangerous 'zombie' cells could increase the number of donor hearts for transplant

SWOG Cancer Research Network clinical trial reveals potential new therapy for Stage 3 or 4 classic Hodgkin lymphoma

Study shows efficacy and safety of novel FolRα-targeting antibody drug conjugate in recurrent epithelial ovarian cancer

Unpacking the nutrient profiles of new-age plant-based foods: Are they truly healthier?

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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