Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

Diabetes Mellitus Type 2 Pathophysiology

Type 2 Diabetes Symptoms

Type 2 Diabetes Diagnosis

Type 2 Diabetes Screening and Prevention

Type 2 Diabetes Treatment

Living With Type 2 Diabetes

Vitamin D and Type 2 Diabetes

Is a Plant-Based Diet Good for Type 2 Diabetes?

Are Low Carbohydrate Diets Good for Type 2 Diabetes?

What is Insulin Resistance?

Insulin Resistance Pathophysiology

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Diabetes in Men versus Women

Insulin Medication

Latest Type 2 Diabetes News and Research

Researchers discover advances in predicting kidney failure in type 1 diabetes patients

In a paper published today in Science Translational Medicine, researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, report that they have discovered advances in predicting kidney failure in type 1 diabetes (T1D) patients.

22 May 2024

Sharp uptick in youth using wegovy and ozempic, study reports

Public interest in weight loss drugs like Wegovy and Ozempic is surging, but national data on dispensing patterns in the United States are surprisingly scarce.

22 May 2024

Substituting dairy with whole grains and olive oil lowers non-communicable disease risk

Review and meta-analysis published in Current Developments in Nutrition examined long-term dietary associations of dairy products and non-communicable diseases (NCDs), finding no significant change in NCD risk with different dairy products but identifying increased risk with red and processed meat substitutions and improved outcomes with whole grains and olive oils.

22 May 2024

New study reveals how genes can alter the cancer-fighting power of fruits and fiber

A study in eBioMedicine uncovers two genetic loci that modify the impact of fiber and fruit intake on colorectal cancer risk, highlighting gene-diet interactions.

22 May 2024

From research to practice: Closing the divide in obesity management

As research continues to produce evidence about the underlying causes of obesity and optimal strategies to treat and manage obesity have evolved, there are disparities in application of the latest scientific advances in the clinical care that people with obesity receive.

20 May 2024

New study identifies key protein biomarkers for early detection of pancreatic cancer

Study used a Mendelian randomization approach to identify REG1A and REG1B as potential biomarkers for early detection of pancreatic cancer, showing their causal effects and significance in cancer screening.

19 May 2024

Web-based self-help program proves effective in treating binge eating disorder

Study shows that web-based cognitive behavioral self-help interventions effectively reduce binge eating episodes and improve overall well-being in individuals with binge eating disorder (BED).

19 May 2024

Understanding the link between high-fat diets, insulin resistance, and diabetic heart disease

The relationship between a high-fat diet and increased risk of Type 2 diabetes and heart disease is well-known. But what is the connection and how does it work?

17 May 2024

Metformin use linked to reduced risk of myeloproliferative neoplasms

People who use metformin are less likely to develop a myeloproliferative neoplasm (MPN) over time, indicating that the treatment may help prevent the development of certain types of cancers, according to a study published in Blood Advances.

17 May 2024

Genetic variants in XDH and SLC2A9 genes linked to T2DM control in Jordanian population

Announcing a new article publication for BIO Integration journal. This study determines the relationships between uric acid levels, specific single nucleotide polymorphisms (SNPs) in genes linked to uric acid metabolism [xanthine dehydrogenase (XDH) and Solute carrier family 2 member 9 (SLC2A9) genes], and control of HbA1c levels in type 2 diabetes mellitus (T2DM) within the Jordanian population.

17 May 2024

Plant-based diets reduce cancer and heart disease risks, study shows

Study reveals that plant-based diets significantly reduce the risks of cancer and cardiometabolic diseases while improving overall health markers.

16 May 2024

Men face higher risk of diabetes complications than women, study finds

Men are at greater risk than women of the major health effects of diabetes (types 1 and 2), suggests a long term study published online in the Journal of Epidemiology & Community Health.

16 May 2024

Text messages with financial rewards boost weight loss in obese men, study finds

Study found that combining behavioral text messages with financial incentives promotes significant weight loss in obese men, while text messages alone do not.

16 May 2024

Anti-obesity medications slash heart disease risk in obese patients, study finds

A study in the journal Obesity evaluated the impact of new anti-obesity medications (AOMs) on cardiovascular disease (CVD) among obese individuals, finding that these medications reduce the risk of CVD complications, particularly heart failure and atrial fibrillation.

15 May 2024

Research quantifies impact of childhood obesity on long-term health and life expectancy

New research being presented at the European Congress on Obesity (ECO) in Venice, Italy (12-15 May) has, for the first time, quantified the impact of different aspects of childhood obesity on long-term health and life expectancy.

15 May 2024

Study proposes lower BMI cut-off for obesity in adults over 40

The internationally recognized body-mass index (BMI) cut-off point for obesity may not be appropriate for middle-aged and older men and women (aged 40-80 years), according to research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May).

15 May 2024

New joint guideline highlights importance of coordinated care for peripheral artery disease

Timely diagnosis and proper management of peripheral artery disease (PAD), including coordinated care from a multispecialty team, are essential to help prevent amputation and other cardiovascular complications and to allow patients with PAD to live longer lives with better physical function and improved quality of life, according to a new joint guideline published today in the American Heart Association's flagship, peer-reviewed journal Circulation and simultaneously in the Journal of the American College of Cardiology.

14 May 2024

Landmark study sheds new light on the heterogeneity of type 2 diabetes

A landmark study by the DZD, published in 'The Lancet Diabetes & Endocrinology', sheds new light on the heterogeneity of type 2 diabetes.

13 May 2024

Semaglutide improves heart failure symptoms and reduces loop diuretic dose

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction (HFpEF) regardless of diuretic use, according to late breaking research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

SHINE trial reveals risks of high blood sugar in post-thrombolysis stroke care

An ambitious, nationwide clinical trial led by UVA Health's Karen Johnston, MD, has provided doctors with long-needed insights into the importance of managing stroke patients' blood sugar after treatment with clot-busting therapy.

13 May 2024