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Mutational signatures in DNA explain genetic development, history of cancers in patients

Researchers have provided the first comprehensive compendium of mutational processes that drive tumour development. Together, these mutational processes explain most mutations found in 30 of the most common cancer types. This new understanding of cancer development could help to treat and prevent a wide-range of cancers.

16 Aug 2013

Investigators link acute viral infections to development of COPD

Investigators at Washington University School of Medicine in St. Louis have described another link in the chain of events that connect acute viral infections to the development of chronic obstructive pulmonary disease (COPD).

16 Aug 2013

Researchers find recurrent genetic mutation linked to deadly thoracic aortic dissections

A multi-institutional team led by Dianna Milewicz, M.D., Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) has found a recurrent genetic mutation that has been linked to deadly thoracic aortic dissections in family members as young as 17 years of age.

16 Aug 2013

Study: Children born to obese mothers are more likely to die early as adults

Children born to obese mothers are more likely to die early as adults than those whose mothers were a normal weight, a study has found.

16 Aug 2013

Gene variant linked with Mediterranean diet pattern prevents stroke

A gene variant strongly associated with development of type 2 diabetes appears to interact with a Mediterranean diet pattern to prevent stroke, report researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University and from the CIBER Fisiopatolog-a de la Obesidad y Nutriciόn in Spain.

14 Aug 2013

Heightened race consciousness linked to higher blood pressure in black Americans

Black patients preoccupied with racial concerns have higher blood pressure than those who aren’t, according to results of new Johns Hopkins-led research. The findings suggest that heightened race consciousness could at least in part account for the disproportionately high rate of hypertension in black Americans — the highest prevalence of any group in the United States and one of the highest rates in the world.

14 Aug 2013

New test hints 3 sodas daily hurt lifespan, reproduction in mice

When mice ate a diet of 25 percent extra sugar - the mouse equivalent of a healthy human diet plus three cans of soda daily - females died at twice the normal rate and males were a quarter less likely to hold territory and reproduce, according to a toxicity test developed at the University of Utah.

14 Aug 2013

Study finds increased ADHD risk in children who have allergy and asthma

The number of children being diagnosed with attention-deficit disorder (ADHD), allergy and asthma is increasing in the United States. And according to a new study, there might be a link between the growth of these three conditions.

14 Aug 2013

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

Cancer in humans is frequently associated with unusually high amounts of one or more proteins responsible for controlling the rate at which cells divide. As an example, excessive amounts of the cyclin-dependent kinase CDK6 are often found in types of cancer such as lymphoma.

14 Aug 2013

Cultural mythologies strongly influence women’s expectations during pregnancy

Morning sickness, shiny hair and bizarre and intense cravings for pickles and ice cream -- what expectations do pregnant women impose on their bodies, and how are those expectations influenced by cultural perspectives on pregnancy? University of Cincinnati researcher Danielle Bessett, an assistant professor of sociology, presented her research at the 108th annual meeting of the American Sociological Association in New York, N.Y.

14 Aug 2013

Regular exercise can give significant mental boost for HIV infected adults

Regular exercise is not only good for health, but can give people living with HIV a significant mental boost. This is according to a study by Dr. David J. Moore and colleagues at the University of California, San Diego (UCSD), published in Springer's Journal of NeuroVirology.

14 Aug 2013

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

X-linked methyl-CpG binding protein 2 plays important role in the regulation of neuronal development, proliferation and maturation, and synaptic regeneration and apoptosis.

13 Aug 2013

Researchers identify clear genetic risk factors in patients with severe epilepsy

Neurologists and epilepsy researchers from NYU Langone Medical Center were among scientists who have 329 random genetic mutations associated with two of the most severe forms of epilepsy, according to a paper published today in Nature.

13 Aug 2013

Study highlights challenges of predicting disease outcomes in warming world

Climate change is already affecting the spread of infectious diseases--and human health and biodiversity worldwide--according to disease ecologists reporting research results in this week's issue of the journal Science.

13 Aug 2013

New research opens door for development of treatments capable of stopping Alzheimer's disease

New research just out in the journal Science Translational Medicine opens the door for the development of treatments capable of stopping Alzheimer's disease (AD) before its first symptoms, that is to say before any crucial damage occurs. In fact, if AD is a devastating disorder it is also an extremely slow one; it takes more than 10 years for the first symptoms to appear making this preclinical period (pre-symptoms) the ideal time to intervene.

13 Aug 2013

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

In 1958 a group of scientists working in Denmark made the striking observation that bacterial cells are about twice as large when they are cultured on a rich nutrient source than when they are cultured on a meager one.

13 Aug 2013

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body's source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Researchers explore potential of neural stem cells to repair brain damage

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body’s source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Learning "grammar" helps determine whether gene gets switched on or not

Researchers have probed deep into the cell's genome, beyond the basic genetic code, to begin learning the "grammar" that helps determine whether or not a gene gets switched on to make the protein it encodes.

13 Aug 2013

School lunch consumption and TV viewing associated with childhood obesity

Among middle-school children, the behaviors most often linked with obesity are school lunch consumption and two hours or more of daily TV viewing, according to a new look at the dramatic increase in childhood obesity.

13 Aug 2013

X linked News and Research

Mutational signatures in DNA explain genetic development, history of cancers in patients

Investigators link acute viral infections to development of COPD

Researchers find recurrent genetic mutation linked to deadly thoracic aortic dissections

Study: Children born to obese mothers are more likely to die early as adults

Gene variant linked with Mediterranean diet pattern prevents stroke

Heightened race consciousness linked to higher blood pressure in black Americans

New test hints 3 sodas daily hurt lifespan, reproduction in mice

Study finds increased ADHD risk in children who have allergy and asthma

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

Cultural mythologies strongly influence women’s expectations during pregnancy

Regular exercise can give significant mental boost for HIV infected adults

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

Researchers identify clear genetic risk factors in patients with severe epilepsy

Study highlights challenges of predicting disease outcomes in warming world

New research opens door for development of treatments capable of stopping Alzheimer's disease

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Researchers explore potential of neural stem cells to repair brain damage

Learning "grammar" helps determine whether gene gets switched on or not

School lunch consumption and TV viewing associated with childhood obesity

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