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UAB researcher awarded NIH grant to study pathogenesis of thrombotic microangiopathy

University of Alabama at Birmingham researcher X. Long Zheng, M.D., Ph.D., has received a five-year, $2.5 million National Institutes of Health grant to study the pathogenesis of thrombotic microangiopathy, or TMA. In simple terms, this means looking for factors that cause or aid the onset of extensive microscopic clots in small blood vessels throughout the body. Though tiny, these spots can damage kidneys, heart and brain, and they can cause death.

29 Oct 2015

Latitude, summer daylight exposure make difference in results for children treated with growth hormone

The rate of growth in children varies with the season while higher latitude and greater summer daylight exposure makes a significant difference in results for children treated with growth hormone, according to new research from The University of Manchester.

29 Oct 2015

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

The New York Stem Cell Foundation announced today that Franziska Michor, PhD, is the 2015 recipient of the NYSCF - Robertson Stem Cell Prize for her work pioneering new approaches to study the growth, spread, and treatment of cancer. Her laboratory fuses her passions in mathematics, molecular biology and patient care to investigate how cancers form and progress.

29 Oct 2015

Biodegradable polymer could help heal the bones of patients with orthopedic injuries

A plastic derived from cornstarch combined with a volcanic ash compound, Montmorillonite clay, could help heal the bones of hundreds of thousands of patients with orthopedic injuries who need bone replacement after tumor removal, spinal fusion surgery or fracture repair.

28 Oct 2015

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

The U.S. Food and Drug Administration today approved Imlygic (talimogene laherparepvec), the first FDA-approved oncolytic virus therapy, for the treatment of melanoma lesions in the skin and lymph nodes.

28 Oct 2015

Galil Medical signs agreement to acquire 100% of Perseon

Galil Medical, the global leader in interventional oncology cryoablation technology, announced today it has entered into an agreement to acquire 100% of Perseon Corporation, a publicly-traded company and a leader in the field of microwave ablation, in an all cash transaction valued at $10.6M. The resulting combined company will be privately owned.

27 Oct 2015

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

The immunosuppressant sirolimus is an effective and safe steroid-sparing therapy for children and young adults with highly treatment-resistant autoimmune blood conditions, according to a study published online today in Blood, the Journal of the American Society of Hematology.

27 Oct 2015

Low-weight, high-repetition resistance training increases bone density in adults

A new research study published in The Journal of Sports Medicine and Physical Fitness finds that low-weight, high-repetition resistance training increases bone mineral density in adults, challenging assumptions that heavy weight-training is required to build bone mineral density. Participants who completed the study experienced up to 8 percent bone mineral density increases in the legs, pelvis, arms and spine.

27 Oct 2015

Common steroid medication does not reduce risk of long-term pain after heart surgery

A common steroid medication does not ease long-term pain at the incision site made during open-heart surgery, according to results of a large multicenter randomized controlled trial being presented at the ANESTHESIOLOGY 2015 annual meeting.

26 Oct 2015

Novel modular partial wrist implant may provide relief for patients with painful wrist arthritis

Studies are underway to determine if a new modular partial wrist replacement will allow for better movement and last longer than traditional implants for people seeking relief from painful wrist arthritis. Although current options such as total wrist replacement and wrist fusion can alleviate pain, patients are often limited in performing certain activities after surgery.

26 Oct 2015

Strensiq approved for treatment of patients with juvenile-onset HPP

Today, the U.S. Food and Drug Administration approved Strensiq (asfotase alfa) as the first approved treatment for perinatal, infantile and juvenile-onset hypophosphatasia (HPP).

24 Oct 2015

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Amgen today announced that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, has adopted a positive opinion recommending that IMLYGIC (talimogene laherparepvec) be granted approval for the treatment of adults with unresectable melanoma that is regionally or distantly metastatic (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral disease.

23 Oct 2015

Potential new drug target for acute myeloid leukemia

New treatment options are badly needed for acute myeloid leukemia, a relatively rare form of cancer. The malignancy begins in the bone marrow, and from there can spread rapidly to the bloodstream, depriving the body of the essential blood cells that carry oxygen and fight infections.

23 Oct 2015

Minimally invasive implant procedure effective for patients with sacroiliac joint dysfunction

A minimally invasive implant procedure is highly effective in reducing pain and disability for patients with sacroiliac joint (SIJ) dysfunction, reports a clinical trial in the November issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

23 Oct 2015

DTR Medical to showcase new Bone Trephine product for paediatric cleft surgery at MEDICA 2015

Award-winning UK manufacturer of innovative and high quality single-use surgical instruments DTR Medical, will showcase its new Bone Trephine product at MEDICA - the world’s largest medical trade fair.

23 Oct 2015

Cochlear implants improve outcomes in infants with profound hearing loss

'Dada' is a first word for many babies. Babbling sounds with consonant-vowel repetitions, such as 'dada,' are common among infants once they reach 8 months old; however, these sounds are not prevalent among infants who have profound hearing loss -- that is, until they receive cochlear implants.

23 Oct 2015

$Cesarean delivery does not reduce fracture risk in newborns with rare bone disorder$

Cesarean delivery does not reduce fracture risk in newborns with rare bone disorder

Cesarean delivery was not associated with decrease in the at-birth fracture rates in infants with osteogenesis imperfecta, a rare bone disorder, said a consortium of researchers led by Baylor College of Medicine.

23 Oct 2015

Researchers use cutting edge genomic methods to explain protective effects of malaria vaccine candidate

An international team led by researchers from the Broad Institute of MIT and Harvard, the Harvard T.H. Chan School of Public Health, and Fred Hutchinson Cancer Research Center have used cutting edge genomic methods to uncover key biological insights that help explain the protective effects of the world's most advanced malaria vaccine candidate, RTS,S/AS01 (RTS,S).

22 Oct 2015

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

NHS Blood and Transplant will start producing stem cells for groundbreaking treatment aimed at combating one of the most serious health problems facing the NHS, diabetic kidney disease.

22 Oct 2015

Leptin gene therapy aids weight loss without significant side effect of bone loss

Delivering the hormone leptin directly to the brain through gene therapy aids weight loss without the significant side effect of bone loss, according to new collaborative research from Oregon State University and University of Florida.

22 Oct 2015

Bone News and Research

UAB researcher awarded NIH grant to study pathogenesis of thrombotic microangiopathy

Latitude, summer daylight exposure make difference in results for children treated with growth hormone

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

Biodegradable polymer could help heal the bones of patients with orthopedic injuries

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

Galil Medical signs agreement to acquire 100% of Perseon

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

Low-weight, high-repetition resistance training increases bone density in adults

Common steroid medication does not reduce risk of long-term pain after heart surgery

Novel modular partial wrist implant may provide relief for patients with painful wrist arthritis

Strensiq approved for treatment of patients with juvenile-onset HPP

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Potential new drug target for acute myeloid leukemia

Minimally invasive implant procedure effective for patients with sacroiliac joint dysfunction

DTR Medical to showcase new Bone Trephine product for paediatric cleft surgery at MEDICA 2015

Cochlear implants improve outcomes in infants with profound hearing loss

Cesarean delivery does not reduce fracture risk in newborns with rare bone disorder

Researchers use cutting edge genomic methods to explain protective effects of malaria vaccine candidate

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

Leptin gene therapy aids weight loss without significant side effect of bone loss

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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